Search Results - "Scarnati, Helen T."

Biochemical and Genetic Characterizations of a Novel Human Immunodeficiency Virus Type 1 Inhibitor That Blocks gp120-CD4 Interactions by Guo, Qi, Ho, Hsu-Tso, Dicker, Ira, Fan, Li, Zhou, Nannan, Friborg, Jacques, Wang, Tao, McAuliffe, Brian V, Wang, Hwei-Gene Heidi, Rose, Ronald E, Fang, Hua, Scarnati, Helen T, Langley, David R, Meanwell, Nicholas A, Abraham, Ralph, Colonno, Richard J, Lin, Pin-Fang

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Inhibition of the Bovine Viral Diarrhoea Virus NS3 Serine Protease by a Boron-Modified Peptidyl Mimetic of its Natural Substrate by Bukhtiyarova, Marina, Rizzo, Christopher J, Kettner, Charles A, Korant, Bruce D, Scarnati, Helen T, King, Robert W

“…Bovine viral diarrhoea virus (BVDV) is closely related to hepatitis C virus (HCV), and has been used as a surrogate virus in drug development for HCV…”
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Selection of a Thiazole Urea-Resistant Variant of Bovine Viral Diarrhoea Virus That Maps to the RNA-Dependent RNA Polymerase by King, Robert W, Scarnati, Helen T, Priestley, E Scott, De Lucca, Indawati, Bansal, Anu, Williams, J Kendall

“…By passing wild type bovine viral diarrhoea virus (BVDV) in increasing concentrations of DPC-A69280–29, a thiazole urea class compound that inhibits BVDV…”
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Identification of a clinical isolate of HIV-1 with an isoleucine at position 82 of the protease which retains susceptibility to protease inhibitors by King, Robert W., Winslow, Dean L., Garber, Sena, Scarnati, Helen T., Bachelor, Lee, Stack, Sylvia, Otto, Michael J.

“…The HIV-1 protease (PR) is essential for the production of mature virions. As such, it has become a target for the development of anti-HIV chemotherapeutics…”
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