Search Results - "Scarcella, Melania"

The Key Role of Lysosomal Protease Cathepsins in Viral Infections by Scarcella, Melania, d’Angelo, Danila, Ciampa, Mariangela, Tafuri, Simona, Avallone, Luigi, Pavone, Luigi Michele, De Pasquale, Valeria

“…Cathepsins encompass a family of lysosomal proteases that mediate protein degradation and turnover. Although mainly localized in the endolysosomal compartment,…”
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Lysosomal positioning diseases: beyond substrate storage by Scerra, Gianluca, De Pasquale, Valeria, Scarcella, Melania, Caporaso, Maria Gabriella, Pavone, Luigi Michele, D'Agostino, Massimo

“…Lysosomal storage diseases (LSDs) comprise a group of inherited monogenic disorders characterized by lysosomal dysfunctions due to undegraded substrate…”
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Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies by De Pasquale, Valeria, Scarcella, Melania, Pavone, Luigi Michele

“…Lysosomal storage diseases (LSDs) are a group of metabolic diseases caused by inborn mutations of lysosomal enzymes, which lead to lysosome substrate…”
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Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in mucopolysaccharidosis IIIB by Scarcella, Melania, Scerra, Gianluca, Ciampa, Mariangela, Caterino, Marianna, Costanzo, Michele, Rinaldi, Laura, Feliciello, Antonio, Anzilotti, Serenella, Fiorentino, Chiara, Renna, Maurizio, Ruoppolo, Margherita, Pavone, Luigi Michele, D’Agostino, Massimo, De Pasquale, Valeria

“…Mucopolysaccharidoses (MPSs) are lysosomal disorders with neurological involvement for which no cure exists. Here, we show that recombinant NK1 fragment of…”
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N‑Substituted l‑Iminosugars for the Treatment of Sanfilippo Type B Syndrome by De Pasquale, Valeria, Esposito, Anna, Scerra, Gianluca, Scarcella, Melania, Ciampa, Mariangela, Luongo, Antonietta, D’Alonzo, Daniele, Guaragna, Annalisa, D’Agostino, Massimo, Pavone, Luigi Michele

“…Sanfilippo syndrome comprises a group of four genetic diseases due to the lack or decreased activity of enzymes involved in heparan sulfate (HS) catabolism. HS…”
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