Search Results - "Scanlon, M J"

Evolution of the grass leaf by primordium extension and petiole-lamina remodeling by Richardson, A E, Cheng, J, Johnston, R, Kennaway, R, Conlon, B R, Rebocho, A B, Kong, H, Scanlon, M J, Hake, S, Coen, E

“…The sheathing leaf found in grasses and other monocots is an evolutionary innovation, yet its origin has been a subject of long-standing debate. Here, we…”
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Stepping in time: Alpha‐mu and beta oscillations during a walking synchronization task by Scanlon, J.E.M., Jacobsen, N.S.J., Maack, M.C., Debener, S.

“…Interpersonal behavioral synchrony is defined as the temporal coordination of action between two or more individuals. Humans tend to synchronize their…”
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Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition by Hilton-Proctor, J.P., Ilyichova, O., Zheng, Z., Jennings, I.G., Johnstone, R.W., Shortt, J., Mountford, S.J., Scanlon, M.J., Thompson, P.E.

“…[Display omitted] N-Methylpyrrolidone is a solvent molecule which has been shown to compete with acetyl-lysine-containing peptides for binding to bromodomains…”
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Substituted 1-methyl-4-phenylpyrrolidin-2-ones – Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors by Hilton-Proctor, J.P., Ilyichova, O., Zheng, Z., Jennings, I.G., Johnstone, R.W., Shortt, J., Mountford, S.J., Scanlon, M.J., Thompson, P.E.

“…N-Methylpyrrolidone is one of several chemotypes that have been described as a mimetic of acetyl-lysine in the development of bromodomain inhibitors. In this…”
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Conformational Selection of Inhibitors and Substrates by Proteolytic Enzymes:  Implications for Drug Design and Polypeptide Processing by Fairlie, David P, Tyndall, Joel D. A, Reid, Robert C, Wong, Allan K, Abbenante, Giovanni, Scanlon, Martin J, March, Darren R, Bergman, Douglas A, Chai, Christina L. L, Burkett, Brendan A

“…Inhibitors of proteolytic enzymes (proteases) are emerging as prospective treatments for diseases such as AIDS and viral infections, cancers, inflammatory…”
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NARROW SHEATH1 functions from two meristematic foci during founder-cell recruitment in maize leaf development by Scanlon, M J

“…The narrow sheath duplicate genes (ns1 and ns2) perform redundant functions during maize leaf development. Plants homozygous for mutations in both ns genes…”
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Effects of Oxidants and Glutamate Receptor Activation on Mitochondrial Membrane Potential in Rat Forebrain Neurons by Scanlon, Joelle M., Reynolds, Ian J.

“…: Both glutamate and reactive oxygen species have been implicated in excitotoxic neuronal injury, and mitochondria may play a key role in the mediation of this…”
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Astrocytes are more resistant than neurons to the cytotoxic effects of increased [Zn(2+)](i) by Dineley, K E, Scanlon, J M, Kress, G J, Stout, A K, Reynolds, I J

“…Increased intracellular free Zn(2+) ([Zn(2+)](i)) is toxic to neurons. Glia are more resistant to Zn(2+)-mediated toxicity; however, it is not known if this is…”
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Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor by Daly, N.L, Scanlon, M.J, Djordjevic, J.T, Kroon, P.A, Smith, R

“…The low-density lipoprotein (LDL) receptor plays a central role in mammalian cholesterol metabolism, clearing lipoproteins which bear apolipoproteins E and…”
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Genetic Analysis of 63 Mutations Affecting Maize Kernel Development Isolated From Mutator Stocks by Scanlon, M. J, Stinard, P. S, James, M. G, Myers, A. M, Robertson, D. S

“…Sixty-three mutations affecting development of the maize kernel were isolated from active Robertson's Mutator (Mu) stocks. At least 14 previously undescribed…”
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Solution Structure of BSTI:  A New Trypsin Inhibitor from Skin Secretions of Bombina bombina by Rosengren, K. Johan, Daly, Norelle L, Scanlon, Martin J, Craik, David J

“…The three-dimensional solution structure of BSTI, a trypsin inhibitor from the European frog Bombina bombina, has been solved using 1H NMR spectroscopy. The 60…”
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Effects of pyrroloquinoline quinone on glutamate-induced production of reactive oxygen species in neurons by Scanlon, Joelle M, Aizenman, Elias, Reynolds, Ian J

“…Pyrroloquinoline quinone may act as a free radical scavenger and also as a modulator of the NMDA receptor associated redox modulatory site. Using the oxidation…”
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Hypersecretion of luteinizing hormone and ovarian steroids in women with recurrent early miscarriage by Watson, H, Kiddy, D S, Hamilton-Fairley, D, Scanlon, M J, Barnard, C, Collins, W P, Bonney, R C, Franks, S

“…Polycystic ovary syndrome is associated with hypersecretion of luteinizing hormone (LH) which has been implicated in the aetiology of early pregnancy loss…”
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Performance enhancement of piezoelectric energy harvesters from wake galloping by Abdelkefi, A., Scanlon, J. M., McDowell, E., Hajj, M. R.

“…Experiments are performed to investigate the effects of wake galloping on the range of flow speeds over which a galloping-based piezoaeroelastic energy…”
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Structural and computational investigations of the conformation of antigenic peptide fragments of human polymorphic epithelial mucin by SCANLON, M. J, MORLEY, S. D, JACKSON, D. E, PRICE, M. R, TENDLER, S. J. B

“…Human polymorphic epithelial mucins (PEM) are complex glycoproteins that are associated with breast and ovarian carcinomas. The PEM core protein consists of…”
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A simplified liquid chromatography assay for the quantitation of halofantrine and desbutylhalofantrine in plasma and identification of a degradation product of desbutylhalofantrine formed under alkaline conditions by Humberstone, Andrew J., Currie, Graeme J., Porter, Christopher J.H., Scanlon, Martin J., Charman, William N.

“…The development of a new and simplified, validated LC assay for the quantitation of halofantrine and desbutylhalofantrine in plasma is described. The…”
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A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein by Anderson, Marilyn A, Lee, Marcus C.S, Scanlon, Martin J, Craik, David J

“…Female reproductive tissues of the ornamental tobacco amass high levels of serine proteinase inhibitors (PIs) for protection against pests and pathogens. These…”
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The maize mutant narrow sheath fails to establish leaf margin identity in a meristematic domain by Scanlon, M J, Schneeberger, R G, Freeling, M

“…The maize mutant narrow sheath (ns) displays a leaf shape and plant stature phenotype that suggests the preprimordial deletion of a leaf domain. The ns mutant…”
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Serum 11 beta-hydroxyandrostenedione as an indicator of the source of excess androgen production in women with polycystic ovaries by Polson, D W, Reed, M J, Franks, S, Scanlon, M J, James, V H

“…Serum 11 beta-hydroxyandrostenedione levels (11-OHA) were measured in normal women and women with polycystic ovaries (PCO) to assess their value in localizing…”
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Pharmacological investigation of mitochondrial ca(2+) transport in central neurons: studies with CGP-37157, an inhibitor of the mitochondrial Na(+)-Ca(2+) exchanger by Scanlon, J M, Brocard, J B, Stout, A K, Reynolds, I J

“…Mitochondria buffer large changes in [Ca(2+)](i)following an excitotoxic glutamate stimulus. Mitochondrial sequestration of [Ca(2+)](i)can beneficially…”
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