Search Results - "Scangos, G A"

Early Regions of JC Virus and BK Virus Induce Distinct and Tissue-Specific Tumors in Transgenic Mice by Small, Judy A., Khoury, George, Jay, Gilbert, Howley, Peter M., Scangos, George A.

“…JC virus and BK virus are ubiquitous human viruses that share sequence and structural homology with simian virus 40. To characterize tissue-specific expression…”
Get full text

Genetic Transformation of Mouse Embryos by Microinjection of Purified DNA by Gordon, Jon W., Scangos, George A., Plotkin, Diane J., Barbosa, James A., Ruddle, Frank H.

“…A recombinant plasmid composed of segments of herpes simplex virus and simian virus 40 viral DNA inserted into the bacterial plasmid pBR322 was microinjected…”
Get full text

Regulatory region of human amyloid precursor protein (APP) gene promotes neuron‐specific gene expression in the CNS of transgenic mice by Wirak, D. O., Bayney, R., Kundel, C. A., Lee, A., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

“…The accumulation of beta‐amyloid protein in specific brain regions is a central pathological feature of Alzheimer's disease (AD). The 4 kd beta‐amyloid protein…”
Get full text

Mechanisms of DNA Uptake by Mammalian Cells: Fate of Exogenously Added DNA Monitored by the Use of Fluorescent Dyes by Loyter, Abraham, Scangos, George A., Ruddle, Frank H.

“…Coprecipitation of DNA with calcium phosphate is a commonly used method of gene transfer in mammalian cells. We have found that DNA forms a tight complex with…”
Get full text

Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice by Wirak, D. O., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

“…Alzheimer's disease is characterized by widespread deposition of amyloid in the central nervous system. The 4-kilodalton amyloid β protein is derived from a…”
Get full text

The early region of human papovavirus JC induces dysmyelination in transgenic mice by Small, J A, Scangos, G A, Cork, L, Jay, G, Khoury, G

“…Transgenic mice containing the early region of human papovavirus JC were produced. Some of these mice exhibited a shaking disorder similar to the previously…”
Get more information

The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice by SMALL, J. A, BIEBERICH, C, GHOTBI, Z, HESS, J, SCANGOS, G. A, CLEMENTS, J. E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Analysis of a transgenic mouse containing simian virus 40 and v-myc sequences by SMALL, J. A, BLAIR, D. G, SHOWALTER, S. D, SCANGOS, G. A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Extinction of JC Virus Tumor-Antigen Expression in Glial Cell-Fibroblast Hybrids by Beggs, Alan H., Frisque, Richard J., Scangos, George A.

“…JC virus (JCV) is a ubiquitous human papovavirus that shares sequence and structural homology with simian virus 40 (SV40). In contrast to SV40, expression of…”
Get full text

Cell type-specific Expression of JC Virus T Antigen in Primary and Established Cell Lines from Transgenic Mice by Beggs, Alan H, Miner, Jeffrey H, Scangos, George A

“…Department of Biology, The Johns Hopkins University, Baltimore, Maryland 21218, U.S.A. The highly restricted host range of JC virus (JCV) has made it difficult…”
Get full text

Dysmyelination in transgenic mice containing JC virus early region by Trapp, B D, Small, J A, Pulley, M, Khoury, G, Scangos, G A

“…JC virus (JCV) causes the chronic human demyelinating disease progressive multifocal leukoencephalopathy. Because of host range restrictions, experimental…”
Get more information

Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability by Scangos, G A, Huttner, K M, Juricek, D K, Ruddle, F H

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Changes in structure and methylation pattern in a cluster of thymidine kinase genes by Christy, B A, Scangos, G A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

In vitro methylation of bovine papillomavirus alters its ability to transform mouse cells by Christy, B A, Scangos, G A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

DNA-Mediated Gene Transfer of a Circular Plasmid into Murine Cells by Huttner, Kenneth M., Scangos, George A., Ruddle, Frank H.

“…We have used DNA-mediated gene transfer to introduce a recombinant plasmid containing the human $\beta $-globin gene (H$_{\beta}$ 1) into cells of a mouse…”
Get full text

Ribitol and D-arabitol catabolism in Escherichia coli by Scangos, G A, Reiner, A M

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Molecular Analysis of Chromosome-Mediated Gene Transfer by Scangos, George A., Huttner, Kenneth M., Silverstein, Saul, Ruddle, Frank H.

“…Metaphase chromosomes isolated from a cell line carrying the thymidine kinase (TK) gene of herpes simplex virus type 1 were used to transform the TK-deficient…”
Get full text

Acquisition of ability to utilize Xylitol: disadvantages of a constitutive catabolic pathway in Escherichia coli by Scangos, G A, Reiner, A M

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

DNA-Mediated Gene Transfer without Carrier DNA by Huttner, Kenneth M., Barbosa, James A., Scangos, George A., Pratcheva, Dimitrina D., Ruddle, Frank H.

“…DNA-mediated gene transfer is a procedure which uses purified DNA to introduce new genetic elements into cells in culture. The standard DNA-mediated gene…”
Get full text

Age-Associated Inclusions in Normal and Transgenic Mouse Brain by Jucker, Mathias, Walker, Lary C., Martin, Lee J., Kitt, Cheryl A., Kleinman, Hynda K., Ingram, Donald K., Price, Donald L., Wirak, D., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

Get full text