Search Results - "Scandura, Grazia"

Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing by Vicario, Nunzio, Spitale, Federica M., Tibullo, Daniele, Giallongo, Cesarina, Amorini, Angela M., Scandura, Grazia, Spoto, Graziana, Saab, Miriam W., D’Aprile, Simona, Alberghina, Cristiana, Mangione, Renata, Bernstock, Joshua D., Botta, Cirino, Gulisano, Massimo, Buratti, Emanuele, Leanza, Giampiero, Zorec, Robert, Vecchio, Michele, Di Rosa, Michelino, Li Volti, Giovanni, Lazzarino, Giuseppe, Parenti, Rosalba, Gulino, Rosario

“…Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In…”
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Mitochondrial Bioenergetics at the Onset of Drug Resistance in Hematological Malignancies: An Overview by Barbato, Alessandro, Scandura, Grazia, Puglisi, Fabrizio, Cambria, Daniela, La Spina, Enrico, Palumbo, Giuseppe Alberto, Lazzarino, Giacomo, Tibullo, Daniele, Di Raimondo, Francesco, Giallongo, Cesarina, Romano, Alessandra

“…The combined derangements in mitochondria network, function and dynamics can affect metabolism and ATP production, redox homeostasis and apoptosis triggering,…”
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CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment by Giallongo, Cesarina, Dulcamare, Ilaria, Tibullo, Daniele, Del Fabro, Vittorio, Vicario, Nunzio, Parrinello, Nunziatina, Romano, Alessandra, Scandura, Grazia, Lazzarino, Giacomo, Conticello, Concetta, Li Volti, Giovanni, Amorini, Angela Maria, Musumeci, Giuseppe, Di Rosa, Michelino, Polito, Francesca, Oteri, Rosaria, Aguennouz, M’hammed, Parenti, Rosalba, Di Raimondo, Francesco, Palumbo, Giuseppe A.

“…Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple myeloma (MM) promote tumor growth, confer chemoresistance and support…”
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Mechanisms of Action of the New Antibodies in Use in Multiple Myeloma by Romano, Alessandra, Storti, Paola, Marchica, Valentina, Scandura, Grazia, Notarfranchi, Laura, Craviotto, Luisa, Di Raimondo, Francesco, Giuliani, Nicola

“…Monoclonal antibodies (mAbs) directed against antigen-specific of multiple myeloma (MM) cells have Fc-dependent immune effector mechanisms, such as…”
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Label-Free Enrichment of Circulating Tumor Plasma Cells: Future Potential Applications of Dielectrophoresis in Multiple Myeloma by Musso, Nicolò, Romano, Alessandra, Bonacci, Paolo Giuseppe, Scandura, Grazia, Pandino, Clarissa, Camarda, Massimo, Russo, Giorgio Ivan, Di Raimondo, Francesco, Cacciola, Emma, Cacciola, Rossella

“…In multiple myeloma (MM), circulating tumor plasma cells (CTPCs) are an emerging prognostic factor, offering a promising and minimally invasive means for…”
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Impact of buffer composition on biochemical, morphological and mechanical parameters: A tare before dielectrophoretic cell separation and isolation by Bonacci, Paolo G., Caruso, Giuseppe, Scandura, Grazia, Pandino, Clarissa, Romano, Alessandra, Russo, Giorgio I., Pethig, Ronald, Camarda, Massimo, Musso, Nicolò

“…•DEP is an electrokinetic approach for discriminating and separating floating cells.•Buffer composition differently influence the viability of Caco-2 and K562…”
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Engagement of Mesenchymal Stromal Cells in the Remodeling of the Bone Marrow Microenvironment in Hematological Cancers by Giallongo, Sebastiano, Duminuco, Andrea, Dulcamare, Ilaria, Zuppelli, Tatiana, La Spina, Enrico, Scandura, Grazia, Santisi, Annalisa, Romano, Alessandra, Di Raimondo, Francesco, Tibullo, Daniele, Palumbo, Giuseppe A, Giallongo, Cesarina

“…Mesenchymal stromal cells (MSCs) are a subset of heterogeneous, non-hematopoietic fibroblast-like cells which play important roles in tissue repair,…”
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P855: FERROPTOSIS AS A NEW BCMA‐TARGETED IMMUNOTHERAPY OFF‐TARGET EFFECT IN MULTIPLE MYELOMA by La Spina, Enrico, Romano, Alessandra, Tibullo, Daniele, Giallongo, Cesarina, Scandura, Grazia, Cambria, Daniela, Giallongo, Sebastiano, Giuseppe Alberto, Palumbo

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TLR4 Signaling and Heme Oxygenase-1/Carbon Monoxide Pathway Crosstalk Induces Resiliency of Myeloma Plasma Cells to Bortezomib Treatment by Scandura, Grazia, Giallongo, Cesarina, Puglisi, Fabrizio, Romano, Alessandra, Parrinello, Nunziatina Laura, Zuppelli, Tatiana, Longhitano, Lucia, Giallongo, Sebastiano, Di Rosa, Michelino, Musumeci, Giuseppe, Motterlini, Roberto, Foresti, Roberta, Palumbo, Giuseppe Alberto, Li Volti, Giovanni, Di Raimondo, Francesco, Tibullo, Daniele

“…Relapse in multiple myeloma (MM) decreases therapy efficiency through unclear mechanisms of chemoresistance. Since our group previously demonstrated that heme…”
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PB2093: OVERALL SURVIVAL IN RELAPSED‐REFRACTORY MYELOMA PATIENTS DEPENDS ON CIRCULATING PLASMA CELLS QUANTITATION by Parrinello, Nunziatina Laura, Scandura, Grazia, Marino, Sara, Triolo, Anna, Del Fabro, Vittorio, DI Raimondo, Francesco, Conticello, Concetta, Romano, Alessandra

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Focus on Osteosclerotic Progression in Primary Myelofibrosis by Spampinato, Mariarita, Giallongo, Cesarina, Romano, Alessandra, Longhitano, Lucia, La Spina, Enrico, Avola, Roberto, Scandura, Grazia, Dulcamare, Ilaria, Bramanti, Vincenzo, Di Rosa, Michelino, Vicario, Nunzio, Parenti, Rosalba, Li Volti, Giovanni, Tibullo, Daniele, Palumbo, Giuseppe A

“…Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by hematopoietic stem-cell-derived clonal proliferation, leading to bone marrow (BM)…”
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P042: Metabolic regulation of adaptive response to arginine deprivation in Hodgkin Lymphoma by Romano, Alessandra, Scandura, Grazia, Santuccio, Gabriella, Puglisi, Fabrizio, Cambria, Daniela, Amorini, Angela Maria, La Spina, Enrico, Parrinello, Nunziatina Laura, Giallongo, Cesarina, Tibullo, Daniele, Cerchione, Claudio, Martinelli, Giovanni, Simonetti, Giorgia, Di Raimondo, Francesco

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P852: ARGININE DEPRIVATION INDUCES ACQUISITION OF A SENESCENT PHENOTYPE AND FAVORS GENOMIC INSTABILITY IN MULTIPLE MYELOMA PLASMA CELLS by Romano, Alessandra, Scandura, Grazia, Giallongo, Cesarina, La Spina, Enrico, Longhitano, Lucia, Zuppelli, Tatiana, Dulcamare, Ilaria, Laura Parrinello, Nunziatina, Polito, Francesca, Oteri, Rosaria, Aguennouz, Mohammed, Vicario, Nunzio, Maria Amorini, Angela, Del Fabro, Vittorio, Conticello, Concetta, Volti, Giovanni LI, Alberto Palumbo, Giuseppe, Tibullo, Daniele, Raimondo, Francesco DI

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Lactate Transporters Modulate Stromal Cell Remodeling in Myeloproliferative Neoplasms (MPN) by Tibullo, Daniele, Spampinato, Mariarita, Duminuco, Andrea, La Spina, Enrico, Giallongo, Sebastiano, Romano, Alessandra, Scandura, Grazia, Zuppelli, Tatiana, Caltabiano, Rosario, Salvatorelli, Lucia, Li Volti, Giovanni, Di Raimondo, Francesco, Giallongo, Cesarina, Palumbo, Giuseppe Alberto

“…Introduction . Philadelphia-negative myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential thrombocythemia (ET), and primary…”
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Lipid Handling Induces Ferroptosis and Conveys Sensitivity to Anti-BCMA Immunotherapy in Multiple Myeloma by La Spina, Enrico, Cortellino, Salvatore, Giallongo, Cesarina, Mecca, Marisabel, Picerno, Simona, Amoresano, Angela, Pinto, Gabriella, Serpico, Stefania, Sgambato, Alessandro, Scandura, Grazia, Cambria, Daniela, Tibullo, Daniele, Neri, Antonino, Di Raimondo, Francesco, Romano, Alessandra

“…Lipid metabolic changes in cancer are attracting increased attention. BAFF/APRIL axis is a multifaceted immune regulator of adipose tissue function and an…”
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An Integrative Unbiased Global Analysis of the Metabolic Adaptive Response to Tryptophan Deprivation in Classical Hodgkin Lymphoma by Puglisi, Fabrizio, La Spina, Enrico, Barbato, Alessandro, Scandura, Grazia, Giallongo, Cesarina, Tibullo, Daniele, Di Raimondo, Francesco, Romano, Alessandra

“…Background Tryptophan (trp) is an essential aminoacid, required for de novo NAD+ synthesis. Our previous work showed that the microenvironment in classical…”
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Arginine Deprivation in Microenvironment Makes Multiple Myeloma Resistant to Proteasome Inhibitors Via Increased Lactate Release and Metabolic Rewiring by Giallongo, Cesarina, Scandura, Grazia, Barbato, Alessandro, La Spina, Enrico, Longhitano, Lucia, Zuppelli, Tatiana, Dulcamare, Ilaria, Parrinello, Nunziatina Laura, Giallongo, Sebastiano, Polito, Francesca, Oteri, Rosaria, Aguennouz, Mohammed, Palumbo, Giuseppe A., Lolicato, Marco, Li Volti, Giovanni, Di Raimondo, Francesco, Tibullo, Daniele, Romano, Alessandra

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CXCL12/CXCR4 Axis Drives Mitochondrial Trafficking in Tumor Myeloma Microenvironment by Giallongo, Cesarina, Dulcamare, Ilaria, Tibullo, Daniele, Del Fabro, Vittorio, Vicario, Nunzio, Parrinello, Nunziatina Laura, Romano, Alessandra, Scandura, Grazia, Barbato, Alessandro, La Spina, Enrico, Cambria, Daniela, Lazzarino, Giacomo, Conticello, Concetta, Li Volti, Giovanni, Musumeci, Giuseppe, Palumbo, Giuseppe A., Di Raimondo, Francesco

“…Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple myeloma (MM) promote tumor growth, confer chemoresistance and support…”
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Dissecting the Adaptive Response to Arginine Deprivation in Hodgkin Lymphoma by Puglisi, Fabrizio, Padella, Antonella, Parrinello, Nunziatina Laura, Scandura, Grazia, Cambria, Daniela, La Spina, Enrico, Barbato, Alessandro, Giallongo, Cesarina, Tibullo, Daniele, Palumbo, Giuseppe A., Cerchione, Claudio, Martinelli, Giovanni, Simonetti, Giorgia, Di Raimondo, Francesco, Romano, Alessandra

“…Background In Hodgkin Lymphoma (HL), neoplastic cells orchestrate an inflammatory microenvironment leading to sterile inflammation, T-cell anergy, and immune…”
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The Heme Oxygenase-1/Carbon Monoxide Pathway Activates TLR4 Signaling Promoting Bortezomib Resistance in Multiple Myeloma Cells by Giallongo, Cesarina, Scandura, Grazia, Barbato, Alessandro, Romano, Alessandra, Puglisi, Fabrizio, Cambria, Daniela, La Spina, Enrico, Musumeci, Giuseppe, Di Rosa, Michelino, Conticello, Concetta, Li Volti, Giovanni, Palumbo, Giuseppe A., Di Raimondo, Francesco, Tibullo, Daniele

“…Heme oxygenase (HO)-1 catalyzes the conversion of heme to biliverdin, iron an d carbon monoxide. In myeloma plasma cells, its expression has been demonstrated…”
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