Search Results - "Scamurra, Ronald W."
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Decreased mutation frequencies among immunoglobulin G variable region genes during viremic HIV-1 infection
Published in PloS one (07-01-2014)“…HIV-1 infection is complicated by high rates of opportunistic infections against which specific antibodies contribute to immune defense. Antibody function…”
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Journal Article -
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Species specialization in cytokine biology: Is interleukin-4 central to the TH1–TH2 paradigm in swine?
Published in Developmental and comparative immunology (01-03-2009)“…The TH1 -TH2 paradigm provides an elegant model of directed response to infectious pathogens. Developed in the mouse, the model has provided a framework for…”
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Antibody-Enhanced Pneumococcal Adherence Requires IgA1 Protease
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2003)“…IgA, the major class of Ig in secretions, classically functions by interfering with microbial attachment to host tissues. Many mucosal pathogens, including…”
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Species specialization in cytokine biology: is interleukin-4 central to the T(H)1-T(H)2 paradigm in swine?
Published in Developmental and comparative immunology (01-03-2009)“…The TH1-TH2 paradigm provides an elegant model of directed response to infectious pathogens. Developed in the mouse, the model has provided a framework for…”
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Journal Article -
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Human Immunodeficiency Virus Type 1 and Mucosal Humoral Defense
Published in The Journal of infectious diseases (01-05-1999)“…Mucosal sites serve as the principle venues through which primary human immunodeficiency virus type 1 (HIV-1) infections are transferred from donor to host…”
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Journal Article Conference Proceeding -
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Mucosal Plasma Cell Repertoire During HIV-1 Infection
Published in The Journal of immunology (1950) (01-10-2002)“…Impaired development of local Ab responses may predispose HIV-1-infected patients to an increased rate, severity, and duration of mucosal infections. We…”
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Inflammatory cytokines in animal health and disease
Published in Veterinary immunology and immunopathology (01-11-1996)“…Inflammatory cytokines, including tumor necrosis factor (TNF), interleukin-1 (IL-1), IL-6 and IL-8, are rapidly induced early in a disease or injury process…”
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Interleukin-4 suppresses inflammatory cytokine gene transcription in porcine macrophages
Published in Journal of leukocyte biology (01-10-1994)“…Inflammatory cytokines, including interleukin (IL)-1 alpha, IL-1 beta, IL-8, and tumor necrosis factor alpha (TNF-alpha) are produced by macrophages in…”
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Impact of HIV-1 Infection on VH3 Gene Repertoire of Naive Human B Cells
Published in The Journal of immunology (1950) (15-05-2000)“…B cells of the largest Ig variable heavy chain gene (VH) family, VH3, are reportedly decreased in patients with late stage HIV-1 disease. This deficit may…”
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Species specialization in cytokine biology: Is interleukin-4 central to the T sub(H)1-T sub(H)2 paradigm in swine?
Published in Developmental and comparative immunology (01-03-2009)“…The T sub(H)1-T sub(H)2 paradigm provides an elegant model of directed response to infectious pathogens. Developed in the mouse, the model has provided a…”
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Journal Article -
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Species specialization in cytokine biology: Is interleukin-4 central to the T H1–T H2 paradigm in swine?
Published in Developmental and comparative immunology (2009)“…The T H1–T H2 paradigm provides an elegant model of directed response to infectious pathogens. Developed in the mouse, the model has provided a framework for…”
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Journal Article -
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Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV-1 Infection: e81913
Published in PloS one (01-01-2014)“…Background/objective HIV-1 infection is complicated by high rates of opportunistic infections against which specific antibodies contribute to immune defense…”
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Journal Article -
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Regulation of interleukin-8 expression in porcine alveolar macrophages by bacterial lipopolysaccharide
Published in The Journal of biological chemistry (07-01-1994)“…Interleukin (IL)-8 is a macrophage-derived neutrophil chemotactic factor that plays an important role in the recruitment of neutrophils to inflammatory loci…”
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Journal Article -
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Regulation of interleukin-6 expression in porcine immune cells
Published in Journal of interferon & cytokine research (01-04-1996)“…Interleukin-6 (IL-6) is a pleiotropic cytokine that regulates the immune response, acute-phase reaction, and hematopoiesis. As a first step in studying the…”
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