Search Results - "Scalzo, A."
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1
The ejected mass distribution of Type Ia supernovae: a significant rate of non-Chandrasekhar-mass progenitors
Published in Monthly notices of the Royal Astronomical Society (11-12-2014)“…The ejected mass distribution of Type Ia supernovae (SNe Ia) directly probes progenitor evolutionary history and explosion mechanisms, with implications for…”
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2
β-Adrenergic signaling drives structural and functional maturation of mouse cardiomyocytes
Published in American Journal of Physiology: Cell Physiology (01-05-2024)“…Cardiac maturation represents the last phase of heart development and is characterized by morphofunctional alterations that optimize the heart for efficient…”
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3
Convolutional neural networks for transient candidate vetting in large-scale surveys
Published in Monthly notices of the Royal Astronomical Society (01-12-2017)“…Abstract Current synoptic sky surveys monitor large areas of the sky to find variable and transient astronomical sources. As the number of detections per night…”
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4
Nearby Supernova Factory Observations of SN 2007if: First Total Mass Measurement of a Super-Chandrasekhar-Mass Progenitor
Published in The Astrophysical journal (20-04-2010)“…We present photometric and spectroscopic observations of SN 2007if, an overluminous (M_V = -20.4), red (B-V = 0.16 at B-band maximum), slow-rising (t_rise = 24…”
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Vital Involvement of a Natural Killer Cell Activation Receptor in Resistance to Viral Infection
Published in Science (American Association for the Advancement of Science) (04-05-2001)“…Natural killer (NK) cells are lymphocytes that can be distinguished from T and B cells through their involvement in innate immunity and their lack of…”
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Functional interactions between dendritic cells and NK cells during viral infection
Published in Nature immunology (01-02-2003)“…Ly49H(+)NK1.1(+) natural killer (NK) cells are essential for the control of murine cytomegalovirus (MCMV) during the acute stage of infection. This cell subset…”
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Recognition of a Virus-Encoded Ligand by a Natural Killer Cell Activation Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2002)“…Natural killer (NK) cells express inhibitory and activation receptors that recognize MHC class I-like molecules on target cells. These receptors may be…”
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Murine Cytomegalovirus m157 Mutation and Variation Leads to Immune Evasion of Natural Killer Cells
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2003)“…Effective natural killer (NK) cell recognition of murine cytomegalovirus (MCMV)-infected cells depends on binding of the Ly49H NK cell activation receptor to…”
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Regulation of Murine Cerebral Malaria Pathogenesis by CD1d-Restricted NKT Cells and the Natural Killer Complex
Published in Immunity (Cambridge, Mass.) (01-03-2003)“…NKT cells are specialized cells coexpressing NK and T cell receptors. Upon activation they rapidly produce high levels of interferon-γ (IFN-γ) and…”
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10
Neuronal cholinergic signaling constrains norepinephrine activity in the heart
Published in American Journal of Physiology: Cell Physiology (01-04-2022)“…It is well known that cholinergic hypofunction contributes to cardiac pathology, yet, the mechanisms involved remain unclear. Our previous study has shown that…”
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11
CD1d-Restricted NKT Cells: An Interstrain Comparison
Published in The Journal of immunology (1950) (01-08-2001)“…CD1d-restricted Valpha14-Jalpha281 invariant alphabetaTCR(+) (NKT) cells are well defined in the C57BL/6 mouse strain, but they remain poorly characterized in…”
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Perforin and Granzymes Have Distinct Roles in Defensive Immunity and Immunopathology
Published in Immunity (Cambridge, Mass.) (01-11-2006)“…Successful control of viral infection requires the host to eliminate the infecting pathogen without causing overt immunopathology. Here we showed that perforin…”
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13
Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells
Published in Nature immunology (01-12-2012)“…NK cell licensing is governed by the interaction of Ly49 receptors with peptide-MHC complexes. Smyth and colleagues show that the nonclassical MHC class I…”
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14
Ly49C-dependent control of MCMV Infection by NK cells is cis-regulated by MHC Class I molecules
Published in PLoS pathogens (01-05-2014)“…Natural Killer (NK) cells are crucial in early resistance to murine cytomegalovirus (MCMV) infection. In B6 mice, the activating Ly49H receptor recognizes the…”
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Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice
Published in PLoS pathogens (01-12-2015)“…Orthopoxviruses (OPV), including variola, vaccinia, monkeypox, cowpox and ectromelia viruses cause acute infections in their hosts. With the exception of…”
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Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth
Published in PloS one (10-09-2009)“…Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize…”
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Perforin Is a Major Contributor to NK Cell Control of Tumor Metastasis
Published in The Journal of immunology (1950) (01-06-1999)“…We provide the first demonstration, using experimental and spontaneous models of metastasis in C57BL/6 (B6) (RM-1 prostate carcinoma) and BALB/c (DA3 mammary…”
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Catalyst-Free Click Chemistry for Engineering Chondroitin Sulfate-Multiarmed PEG Hydrogels for Skin Tissue Engineering
Published in Journal of functional biomaterials (18-04-2022)“…The quest for an ideal biomaterial perfectly matching the microenvironment of the surrounding tissues and cells is an endless challenge within biomedical…”
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The contribution of natural killer complex loci to the development of experimental cerebral malaria
Published in PloS one (01-04-2014)“…The Natural Killer Complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function. The NKC is…”
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Cmv1 and natural killer cell responses to murine cytomegalovirus infection
Published in Current topics in microbiology and immunology (2008)“…The dissection of genetic resistance to murine cytomegalovirus infection in inbred laboratory mouse strains led to the identification of a natural killer cell…”
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