Search Results - "Scallet, A C"

Developmental Neurotoxicity of Ketamine: Morphometric Confirmation, Exposure Parameters, and Multiple Fluorescent Labeling of Apoptotic Neurons by Scallet, A. C., Schmued, L. C., Slikker, W., Grunberg, N., Faustino, P. J., Davis, H., Lester, D., Pine, P. S., Sistare, F., Hanig, J. P.

“…Ketamine is a widely used pediatric anesthetic recently reported (C. Ikonomidou et al., 1999, Science 283, 70–74) to enhance neuronal death in neonatal rats…”
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Increased Volume of the Calbindin D28k-Labeled Sexually Dimorphic Hypothalamus in Genistein and Nonylphenol-Treated Male Rats by Scallet, A. C., Divine, R. L., Newbold, R. R., Delclos, K. B.

“…The adult rat brain develops through an interplay of neuronal proliferation and programmed cell death. Steroid hormones and growth factors may alter the…”
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Ketamine-Induced Neuronal Cell Death in the Perinatal Rhesus Monkey by Slikker, William, Zou, Xiaoju, Hotchkiss, Charlotte E., Divine, Rebecca L., Sadovova, Natalya, Twaddle, Nathan C., Doerge, Daniel R., Scallet, Andrew C., Patterson, Tucker A., Hanig, Joseph P., Paule, Merle G., Wang, Cheng

“…Ketamine is widely used as a pediatric anesthetic. Studies in developing rodents have indicated that ketamine-induced anesthesia results in brain cell death…”
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Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons by Schmued, Larry C., Stowers, Chris C., Scallet, Andrew C., Xu, Lulu

“…The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing…”
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Gender-Based Differences in Rats after Chronic Dietary Exposure to Genistein by Slikker, W., Scallet, A. C., Doerge, D. R., Ferguson, S. A.

“…Gender-based differences can be observed from pharmacokinetic, behavioral, or anatomical assessments. No single assessment tool will provide a complete answer,…”
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Domoic acid-treated cynomolgus monkeys (M. fascicularis): effects of dose on hippocampal neuronal and terminal degeneration by Scallet, A C, Binienda, Z, Caputo, F A, Hall, S, Paule, M G, Rountree, R L, Schmued, L, Sobotka, T, Slikker, Jr, W

“…Domoic acid is a tricarboxylic amino acid (structurally related to kainic acid and glutamic acid) that is found in the environment as a contaminant of some…”
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Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals by Scallet, A C

“…Several laboratories have reported that chronic exposure to delta-9-tetrahydrocannabinol (THC) or marijuana extracts persistently altered the structure and…”
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Developmental neurotoxicity of endocrine disrupters: focus on estrogens by Ferguson, S A, Scallet, A C, Flynn, K M, Meredith, J M, Schwetz, B A

“…A number of different environmental compounds are proposed to interact with the endocrine system (i.e., endocrine disrupters). Many of these have estrogenic…”
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Biomarkers of 3-Nitropropionic Acid (3-NPA)-Induced Mitochondrial Dysfunction as Indicators of Neuroprotection by SCALLET, A.C., NONY, P.L., ROUNTREE, R.L., BINIENDA, Z.K.

“…: In humans or animals, symptoms of mitochondrial energy dysfunction may be produced by mutations or inborn errors of the necessary enzymes, as well as by…”
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3-Nitropropionic acid (3-NPA) produces hypothermia and inhibits histochemical labeling of succinate dehydrogenase (SDH) in rat brain by NONY, P. A, SCALLET, A. C, ROUNTREE, R. L, YE, X, BINIENDA, Z

“…3-Nitropropionic acid (3-NPA) is a toxin sometimes produced on moldy crops (sugarcane, peanuts, etc.) in amounts sufficient to cause severe neurological…”
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"Isolation stress" revisited: isolation-rearing effects depend on animal care methods by Holson, R R, Scallet, A C, Ali, S F, Turner, B B

“…Early reports of enhanced behavioral reactivity in isolation-reared rats attributed this syndrome to "isolation stress." In the studies reported here, this…”
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Domoic acid: Neurobehavioral and neurohistological effects of low-dose exposure in adult rats by Sobotka, T.J., Brown, R., Quander, D.Y., Jackson, R., Smith, M., Long, S.A., Barton, C.N., Rountree, R.L., Hall, S., Eilers, P., Johannessen, J.N., Scallet, A.C.

“…Adult rats treated IP with domoic acid at 0, 0.22, 0.65, or 1.32 mg/kg were tested for passive avoidance (PA), auditory startle (AS), or conditioned avoidance…”
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The 139H scrapie agent produces hypothalamic neurotoxicity and pancreatic islet histopathology: electron microscopic studies by Ye, X, Scallet, A C, Carp, R I

“…Neuronal degeneration, along with astrocytosis, spongiform vacuolation, and amyloid (PrPSc) formation, have long been regarded as neuropathological hallmarks…”
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Ontogeny of the N-Methyl-D-Aspartate (NMDA) Receptor System and Susceptibility to Neurotoxicity by Haberny, Kathleen A., Paule, Merle G., Scallet, Andrew C., Sistare, Frank D., Lester, David S., Hanig, Joseph P., Slikker, William

“…The NMDA receptor has been widely investigated in recent years as a target for the pharmacological management of seizures, pain and a variety of neurological…”
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Quantitating silver-stained neurodegeneration: the neurotoxicity of trimethlytin (TMT) in aged rats by Scallet, Andrew C, Pothuluri, Nomita, Rountree, Robert L, Matthews, John C

“…This report describes the development of a histoanalytical procedure to measure the degree of neurodegeneration produced by the organometal toxicant…”
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Domoic acid-induced neuronal degeneration in the primate forebrain revealed by degeneration specific histochemistry by Schmued, Larry C., Scallet, Andrew C., Slikker, William

“…Domoic acid is a potent excitotoxin produced by diatoms which is subsequently passed along the marine food chain. Its chemical structure and toxicological…”
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Chronic marijuana smoke exposure in the rhesus monkey. II: Effects on progressive ratio and conditioned position responding by Paule, M G, Allen, R R, Bailey, J R, Scallet, A C, Ali, S F, Brown, R M, Slikker, Jr, W

“…Sixty-two male rhesus monkeys were trained to respond in an operant test battery that included tasks thought to allow measurement of aspects of motivation and…”
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Comparison of NADPH diaphorase activity in the brains of hamsters infected with scrapie strains 139H or 263K or with normal hamster brain homogenate by Ye, X, Meeker, H C, Scallet, A C, Carp, R I

“…Previous studies showed that the histopathological changes found in the brains of scrapie-infected animals included amyloid plaque formation, vacuolation,…”
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Morphometric studies of the rat hippocampus following chronic delta-9-tetrahydrocannabinol (THC) by Scallet, A C, Uemura, E, Andrews, A, Ali, S F, McMillan, D E, Paule, M G, Brown, R M, Slikker, Jr, W

“…Persistent behavioral effects resembling those of hippocampal brain lesions have been reported following chronic administration of marijuana or its major…”
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Interactions of MK-801 with glutamate-, glutamine- and methamphetamine-evoked release of [3H]dopamine from striatal slices by Bowyer, J F, Scallet, A C, Holson, R R, Lipe, G W, Slikker, Jr, W, Ali, S F

“…The interactions of MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine], glutamate and glutamine with methamphetamine (METH)-evoked…”
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