Search Results - "Scaglione, Luca"
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The Refeeding Syndrome: a neglected but potentially serious condition for inpatients. A narrative review
Published in Internal and emergency medicine (01-01-2021)“…The Refeeding Syndrome (RFS) is a potentially serious, but still overlooked condition, occurring in individuals who are rapidly fed after a period of severe…”
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One-step NGS molecular analysis of the CFTR gene on newborn dried blood spots gives a higher diagnostic sensitivity in affected and carrier subjects: A pilot study
Published in Clinica chimica acta (01-01-2024)“…Cystic fibrosis is the most common hereditary recessive disease with an incidence of about 1:2500/3000. It has long been known that the disease is caused by…”
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Pharmacokinetics Profile and Genetics of Double Antiviral Therapy with Remdesivir and Nirmatrelvir/Ritonavir for Prolonged COVID-19 in Patients Treated with Rituximab: A Real-Life Study and Literature Review
Published in Future pharmacology (01-03-2024)“…Introduction: Patients with hematologic malignancies are more likely to develop severe and prolonged SARS-CoV-2 infection, often showing viral persistence…”
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Nasopharyngeal Microbiome Signature in COVID-19 Positive Patients: Can We Definitively Get a Role to Fusobacterium periodonticum ?
Published in Frontiers in cellular and infection microbiology (15-02-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the pandemic Coronavirus Disease 2019 (COVID-19). This virus is highly transmissible among…”
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The healing process of diabetic ulcers correlates with changes in the cutaneous microbiota
Published in Scientific reports (12-11-2024)“…Skin microbiota plays an essential role in the development and function of the cutaneous immune system, in the maintenance of the skin barrier through the…”
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Enhanced NAMPT-Mediated NAD Salvage Pathway Contributes to Psoriasis Pathogenesis by Amplifying Epithelial Auto-Inflammatory Circuits
Published in International journal of molecular sciences (01-07-2021)“…Dysregulated cross-talk between immune cells and epithelial compartments is responsible for the onset and amplification of pathogenic auto-inflammatory…”
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Impact of an empiric antimicrobial therapy manual on antimicrobial usage and multidrug resistant organism trends in a large Italian teaching hospital
Published in Infection prevention in practice (01-06-2022)“…To evaluate the changes in antimicrobial consumption and multidrug-resistant microorganism trends after introducing an empiric antimicrobial therapy manual to…”
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Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA
Published in Nucleic acids research (01-03-2013)“…Nucleophosmin (NPM1) is an abundant nucleolar protein implicated in ribosome maturation and export, centrosome duplication and response to stress stimuli. NPM1…”
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THE STORM (acute coronary Syndrome in paTients end Of life and Risk assesMent) study
Published in Emergency medicine journal : EMJ (01-01-2016)“…Elderly patients with coexisting frailty and multiple comorbidities frequently present to the emergency department (ED). Because non-cardiovascular…”
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Identification of immunological patterns characterizing immune-related psoriasis reactions in oncological patients in therapy with anti-PD-1 checkpoint inhibitors
Published in Frontiers in immunology (01-03-2024)“…Immunotherapy with biologics targeting programmed cell death protein-1 (PD-1) is highly effective in the treatment of various malignancies. Nevertheless, it is…”
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A Whole Germline BRCA2 Gene Deletion: How to Learn from CNV In Silico Analysis
Published in International journal of molecular sciences (23-03-2018)“…screening in Hereditary Breast and Ovarian Syndrome (HBOC) is an essential step for effective patients' management. Next-Generation Sequencing (NGS) can…”
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COVID-19 Vaccine: A Potential Risk Factor for Accelerating the Onset of Bullous Pemphigoid
Published in Vaccines (Basel) (05-09-2024)“…Bullous pemphigoid (BP) is the most common autoimmune bullous disease, whose main autoantigens are hemidesmosomal components BP180 and BP230. Although recent…”
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Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis
Published in Vaccines (Basel) (21-11-2022)“…Several biologic therapies have been developed to treat moderate-to-severe psoriasis, with patients exhibiting different clinical benefits, possibly due to the…”
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PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis
Published in Cells (Basel, Switzerland) (02-10-2021)“…The phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway is aberrantly activated in psoriatic lesions and contributes to disease pathogenesis…”
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Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development
Published in The journal of pathology. Clinical research (01-01-2020)“…Immunomodulation with anti‐TNF‐α is highly effective in the treatment of various immune‐mediated inflammatory diseases, including hidradenitis suppurativa…”
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Case Report: Detection of a Novel Germline PALB2 Deletion in a Young Woman With Hereditary Breast Cancer: When the Patient's Phenotype History Doesn't Lie
Published in Frontiers in oncology (24-02-2021)“…The partner and localizer of ( ) is a major binding partner that participates in homologous recombination repair in response to DNA double-strand breaks…”
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Implementing hospital guidelines improves warfarin use in non-valvular atrial fibrillation: a before-after study
Published in BMC public health (10-08-2007)“…The use of oral anticoagulant therapy (OAT) to prevent non-valvular atrial fibrillation (NVAF) related-strokes is often sub-optimal. We aimed to evaluate…”
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Acute myocardial infarction in young adults: Prognostic role of angiotensin-converting enzyme, angiotensin II type I receptor, apolipoprotein E, endothelial constitutive nitric oxide synthase, and glycoprotein IIIa genetic polymorphisms at medium-term follow-up
Published in The American heart journal (01-06-2000)“…Background A number of reports have investigated the association between various gene polymorphisms and the phenotypic expression of myocardial infarction. No…”
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Role of asymmetric-dimethyl- l -arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus
Published in Diabetes research and clinical practice (01-12-2009)“…Abstract Aims To explore the role of asymmetric-dimethyl- l -arginine (ADMA), an endogenous nitric oxide synthetases (NOS) inhibitor, and nitrite/nitrate (NOx)…”
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Incidental Finding of a Homozygous p.M348K Asymptomatic Italian Patient Confirms the Many Faces of Cystic Fibrosis
Published in Case reports in genetics (01-01-2015)“…Cystic fibrosis (CF; OMIM number 219700) is an autosomal recessive disease caused by mutations in the CFTR (cystic fibrosis transmembrane conductance…”
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