Search Results - "Scaglione, G L"
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MITO END-3: efficacy of avelumab immunotherapy according to molecular profiling in first-line endometrial cancer therapy
Published in Annals of oncology (01-07-2024)“…Immunotherapy combined with chemotherapy significantly improves progression-free survival (PFS) compared to first-line chemotherapy alone in advanced…”
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β2‐Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions
Published in Journal of thrombosis and haemostasis (01-06-2013)“…Summary Background This work was aimed at characterizing the interaction of β2‐glycoprotein I (β2GPI), an abundant plasma protein of unknown function, with…”
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Alternative academic approaches for testing homologous recombination deficiency in ovarian cancer in the MITO16A/MaNGO-OV2 trial
Published in ESMO open (01-10-2022)“…The detection of homologous recombination deficiency (HRD) can identify patients who are more responsive to platinum and poly ADP ribose polymerase inhibitors…”
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The type 2B p.R1306W natural mutation of von Willebrand factor dramatically enhances the multimer sensitivity to shear stress
Published in Journal of thrombosis and haemostasis (01-09-2013)“…Summary Background Shear stress triggers conformational stretching of von Willebrand factor (VWF), which is responsible for its self‐association and binding to…”
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Oxidized von Willebrand factor is efficiently cleaved by serine proteases from primary granules of leukocytes: divergence from ADAMTS‐13
Published in Journal of thrombosis and haemostasis (01-08-2011)“…To cite this article: Lancellotti S, De Filippis V, Pozzi N, Oggianu L, Rutella S, Scaglione GL, Maset F, Peyvandi F, Mannucci PM, De Cristofaro R. Oxidized…”
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[beta]2-Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions
Published in Journal of thrombosis and haemostasis (01-06-2013)“…Summary Background This work was aimed at characterizing the interaction of [beta]2-glycoprotein I ([beta]2GPI), an abundant plasma protein of unknown…”
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rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled Trial
Published in The Journal of pediatrics (01-03-2019)“…To investigate recombinant human insulin-like growth factor 1 complexed with its binding protein (rhIGF-1/rhIGFBP-3) for the prevention of retinopathy of…”
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