Search Results - "Scabilloni, James F"
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Extrapulmonary transport of MWCNT following inhalation exposure
Published in Particle and fibre toxicology (09-08-2013)“…Inhalation exposure studies of mice were conducted to determine if multi-walled carbon nanotubes (MWCNT) distribute to the tracheobronchial lymphatics,…”
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Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes
Published in Particle and fibre toxicology (22-07-2011)“…Multi-walled carbon nanotubes (MWCNTs) are new manufactured nanomaterials with a wide spectrum of commercial applications. To address the hypothesis that…”
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Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes
Published in Particle and fibre toxicology (04-10-2010)“…Multi-walled carbon nanotubes (MWCNT) are new manufactured nanomaterials with a wide spectrum of commercial applications. The durability and fiber-like…”
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4
Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes
Published in Particle and fibre toxicology (30-07-2013)“…Prior studies have demonstrated a rapid and progressive acute phase response to bolus aspiration of multi-walled carbon nanotubes (MWCNTs). In this study we…”
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Induction of secondary apoptosis, inflammation, and lung fibrosis after intratracheal instillation of apoptotic cells in rats
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2006)“…Uncontrolled apoptosis has been associated with several pulmonary disorders; however, the molecular mechanism underlying this process and the fate of apoptotic…”
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Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2005)“…Matrix metalloproteinases (MMPs) are the principle enzymes that initiate degradation of collagen. We examined the role of MMPs during alveolar wall fibrosis…”
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Potential role of apoptotic macrophages in pulmonary inflammation and fibrosis
Published in Journal of cellular physiology (01-02-2003)“…Induction of apoptosis has been associated with a variety of exposures which result in inflammatory and fibrotic lung disorders. Macrophages are key regulatory…”
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Direct Fibrogenic Effects of Dispersed Single-Walled Carbon Nanotubes on Human Lung Fibroblasts
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2010)“…Nanomaterials, including single-walled carbon nanotubes (SWCNT), are being developed for a variety of commercial products. However, adverse health effects…”
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Apoptosis and Bax Expression Are Increased by Coal Dust in the Polycyclic Aromatic Hydrocarbon-Exposed Lung
Published in Environmental health perspectives (01-09-2006)“…Background: Miners inhaling respirable coal dust (CD) frequently develop coal workers' pneumoconiosis, a dust-associated pneumoconiosis characterized by lung…”
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Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family
Published in Particle and fibre toxicology (21-06-2016)“…Graphene, a monolayer of carbon, is an engineered nanomaterial (ENM) with physical and chemical properties that may offer application advantages over other…”
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Lung toxicity and biodistribution of Cd/Se-ZnS quantum dots with different surface functional groups after pulmonary exposure in rats
Published in Particle and fibre toxicology (04-03-2013)“…The potential use of quantum dots (QD) in biomedical applications, as well as in other systems that take advantage of their unique physiochemical properties,…”
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The Fate of Inhaled Nanoparticles: Detection and Measurement by Enhanced Dark-field Microscopy
Published in Toxicologic pathology (01-01-2018)“…Assessing the potential health risks for newly developed nanoparticles poses a significant challenge. Nanometer-sized particles are not generally detectable…”
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Role of lung surfactant in phagocytic clearance of apoptotic cells by macrophages in rats
Published in Laboratory investigation (01-05-2006)“…Two of the common features of inflammatory lung diseases are the increased production of pulmonary surfactant and the induction of lung cell apoptosis…”
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