Search Results - "Sbrini, Giulia"

Acute Stress Induces Cognitive Improvement in the Novel Object Recognition Task by Transiently Modulating Bdnf in the Prefrontal Cortex of Male Rats by Brivio, Paola, Sbrini, Giulia, Riva, Marco Andrea, Calabrese, Francesca

“…Stress response involves several mechanisms and mediators that allow individuals to adapt to a changing environment. The effects of stress may be adaptive or…”
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Central nervous system interaction and crosstalk between nAChRs and other ionotropic and metabotropic neurotransmitter receptors by Bono, Federica, Fiorentini, Chiara, Mutti, Veronica, Tomasoni, Zaira, Sbrini, Giulia, Trebesova, Hanna, Marchi, Mario, Grilli, Massimo, Missale, Cristina

“…Neuronal nicotinic acetylcholine receptors (nAChRs) are widely distributed in both the peripheral and the central nervous systems. nAChRs exert a crucial…”
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Chronic Restraint Stress Inhibits the Response to a Second Hit in Adult Male Rats: A Role for BDNF Signaling by Brivio, Paola, Sbrini, Giulia, Corsini, Giulia, Paladini, Maria Serena, Racagni, Giorgio, Molteni, Raffaella, Calabrese, Francesca

“…Depression is a recurrent disorder, with about 50% of patients experiencing relapse. Exposure to stressful events may have an adverse impact on the long-term…”
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Centella asiatica L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex by Sbrini, Giulia, Brivio, Paola, Fumagalli, Marco, Giavarini, Flavio, Caruso, Donatella, Racagni, Giorgio, Dell'Agli, Mario, Sangiovanni, Enrico, Calabrese, Francesca

“…A wide range of people in the world use natural remedies as primary approaches against illnesses. Accordingly, understanding the mechanisms of action of…”
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Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone by Brivio, Paola, Sbrini, Giulia, Tarantini, Letizia, Parravicini, Chiara, Gruca, Piotr, Lason, Magdalena, Litwa, Ewa, Favero, Chiara, Riva, Marco Andrea, Eberini, Ivano, Papp, Mariusz, Bollati, Valentina, Calabrese, Francesca

“…Epigenetics is one of the mechanisms by which environmental factors can alter brain function and may contribute to central nervous system disorders…”
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Peripheral Serotonin Deficiency Affects Anxiety-like Behavior and the Molecular Response to an Acute Challenge in Rats by Sbrini, Giulia, Hanswijk, Sabrina I, Brivio, Paola, Middelman, Anthonieke, Bader, Michael, Fumagalli, Fabio, Alenina, Natalia, Homberg, Judith R, Calabrese, Francesca

“…Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in…”
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TPH2 Deficiency Influences Neuroplastic Mechanisms and Alters the Response to an Acute Stress in a Sex Specific Manner by Brivio, Paola, Sbrini, Giulia, Peeva, Polina, Todiras, Mihail, Bader, Michael, Alenina, Natalia, Calabrese, Francesca

“…Dysregulations of the central serotoninergic system have been implicated in several psychopathologies, characterized by different susceptibility between males…”
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Generation of human induced pluripotent stem cell lines derived from three Noonan syndrome patients from a single family carrying the heterozygous PTPN11 c.188 A > G (p.Y63C) mutation by Sbrini, Giulia, Tomasoni, Zaira, Cutrì, Maria Rosa, Pilotta, Alba, Mingotti, Chiara, Badolato, Raffaele, La Via, Luca, Barbon, Alessandro, Bono, Federica, Fiorentini, Chiara

“…We have established Noonan syndrome (NS)-derived induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of a family…”
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The Absence of Serotonin in the Brain Alters Acute Stress Responsiveness by Interfering With the Genomic Function of the Glucocorticoid Receptors by Sbrini, Giulia, Brivio, Paola, Peeva, Polina Mineva, Todiras, Mihail, Bader, Michael, Alenina, Natalia, Calabrese, Francesca

“…psychiatric pathologies, such as depression. We took advantage of tryptophan hydroxylase (TPH) 2 deficient rats, characterized by a complete absence of…”
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G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2 by Bono, Federica, Tomasoni, Zaira, Mutti, Veronica, Sbrini, Giulia, Kumar, Rajesh, Longhena, Francesca, Fiorentini, Chiara, Missale, Cristina

“…The heteromer composed of dopamine D1 and D3 receptors (D1R-D3R) has been defined as a structure able to trigger Erk1/2 and Akt signaling in a G…”
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Chronic Treatment with a Phytosomal Preparation Containing Centella asiatica L. and Curcuma longa L. Affects Local Protein Synthesis by Modulating the BDNF-mTOR-S6 Pathway by Sbrini, Giulia, Brivio, Paola, Sangiovanni, Enrico, Fumagalli, Marco, Racagni, Giorgio, Dell'Agli, Mario, Calabrese, Francesca

“…Brain derived neurotrophic factor (Bdnf) is the most diffuse neurotrophin in the central nervous system and it is crucial for the proper brain development and…”
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17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons by Sbrini, Giulia, Mutti, Veronica, Bono, Federica, Tomasoni, Zaira, Fadel, Dounia, Missale, Cristina, Fiorentini, Chiara

“…Dopaminergic neurons express a heteromer composed of the dopamine D3 receptor and the α4β2 nicotinic acetylcholine receptor, the D3R-nAChR heteromer, activated…”
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Deficiency of serotonin at central or peripheral level alters neuroplastic and epigenetic mechanisms in adult rats by Sbrini, Giulia, Brivio, Paola, Alenina, Natalia, Homberg, Judith, Calabrese, Francesca

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Repeated testing modulates chronic unpredictable mild stress effects in male rats by Bosch, Kari, Sbrini, Giulia, Burattini, Irene, Nieuwenhuis, Desirée, Calabrese, Francesca, Schubert, Dirk, Henckens, Marloes J.A.G., Homberg, Judith R.

“…Depression is a highly prevalent, debilitating mental disorder. Chronic unpredictable mild stress (CUMS) is the most widely applied model to study this…”
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Enrichment Environment Positively Influences Depression- and Anxiety-Like Behavior in Serotonin Transporter Knockout Rats through the Modulation of Neuroplasticity, Spine, and GABAergic Markers by Sbrini, Giulia, Brivio, Paola, Bosch, Kari, Homberg, Judith Regina, Calabrese, Francesca

“…The serotonin transporter (5-HTT in humans, SERT in rodents) is the main regulator of serotonergic transmission in the brain. The short allelic variant of the…”
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Effect of lurasidone treatment on chronic mild stress-induced behavioural deficits in male rats: The potential role for glucocorticoid receptor signalling by Calabrese, Francesca, Brivio, Paola, Sbrini, Giulia, Gruca, Piotr, Lason, Magdalena, Litwa, Ewa, Niemczyk, Monika, Papp, Mariusz, Riva, Marco A

“…Background: Stress represents one of the main precipitating factors for psychiatric diseases, characterised by an altered function of glucocorticoid receptors…”
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Tryptophan Hydroxylase 2 Knockout Male Rats Exhibit a Strengthened Oxytocin System, Are Aggressive, and Are Less Anxious by Meng, Xianzong, Grandjean, Joanes, Sbrini, Giulia, Schipper, Pieter, Hofwijks, Nita, Stoop, Jesse, Calabrese, Francesca, Homberg, Judith

“…The central serotoninergic system is critical for stress responsivity and social behavior, and its dysregulations have been centrally implicated in virtually…”
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Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function by Bono, Federica, Mutti, Veronica, Tomasoni, Zaira, Sbrini, Giulia, Missale, Cristina, Fiorentini, Chiara

“…G protein-coupled receptors (GPCR) heterodimers represent new entities with unique pharmacological, signalling, and trafficking properties, with specific…”
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S134. Glucocorticoid Receptor Signaling and Cognitive Dysfunction in the Rat Chronic Mild Stress Model: Restorative Effects of Prolonged Lurasidone Treatment by Calabrese, Francesca, Brivio, Paola, Sbrini, Giulia, Papp, Mariusz, Niemczyk, Monika, Lason, Magdalena, Gruca, Piotr, Riva, Marco

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F99. Serotonin Deficiency in the Central Nervous System Alters Epigenetics Mechanisms During Brain Development and at Adulthood by Brivio, Paola, Sbrini, Giulia, Peeva, Polina, Todiras, Mihail, Alenina, Natalia, Calabrese, Francesca

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