Search Results - "Sayedahmed, Ekramy E"

Progress towards the Development of a Universal Influenza Vaccine by Wang, Wen-Chien, Sayedahmed, Ekramy E, Sambhara, Suryaprakash, Mittal, Suresh K

“…Influenza viruses are responsible for millions of cases globally and significantly threaten public health. Since pandemic and zoonotic influenza viruses have…”
Get full text

Significance of Preexisting Vector Immunity and Activation of Innate Responses for Adenoviral Vector-Based Therapy by Wang, Wen-Chien, Sayedahmed, Ekramy E, Mittal, Suresh K

“…An adenoviral (AdV)-based vector system is a promising platform for vaccine development and gene therapy applications. Administration of an AdV vector elicits…”
Get full text

miRNome expression analysis in canine diffuse large B-cell lymphoma by Elshafie, Nelly O., Gribskov, Michael, Lichti, Nathanael I., Sayedahmed, Ekramy. E., Childress, Michael O., dos Santos, Andrea P.

“…Lymphoma is a common canine cancer with translational relevance to human disease. Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype,…”
Get full text

Nonhuman Adenoviral Vector-Based Platforms and Their Utility in Designing Next Generation of Vaccines for Infectious Diseases by Alhashimi, Marwa, Elkashif, Ahmed, Sayedahmed, Ekramy E, Mittal, Suresh K

“…Several human adenoviral (Ad) vectors have been developed for vaccine delivery owing to their numerous advantages, including the feasibility of different…”
Get full text

Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines by Sayedahmed, Ekramy E, Elkashif, Ahmed, Alhashimi, Marwa, Sambhara, Suryaprakash, Mittal, Suresh K

“…Ever since the discovery of vaccines, many deadly diseases have been contained worldwide, ultimately culminating in the eradication of smallpox and polio,…”
Get full text

Vaccine approaches conferring cross-protection against influenza viruses by Vemula, Sai V, Sayedahmed, Ekramy E, Sambhara, Suryaprakash, Mittal, Suresh K

“…Annual vaccination is one of the most efficient and cost-effective strategies to prevent and control influenza epidemics. Most of the currently available…”
Get full text

Enhancement of mucosal innate and adaptive immunity following intranasal immunization of mice with a bovine adenoviral vector by Sayedahmed, Ekramy E, Elshafie, Nelly O, Zhang, GuangJun, Mohammed, Sulma I, Sambhara, Suryaprakash, Mittal, Suresh K

“…Nonhuman adenoviral (AdV) gene delivery platforms have significant value due to their ability to elude preexisting AdV vector immunity in most individuals…”
Get full text

Adenovirus vector-based multi-epitope vaccine provides partial protection against H5, H7, and H9 avian influenza viruses by Hassan, Ahmed O, Amen, Omar, Sayedahmed, Ekramy E, Vemula, Sai V, Amoah, Samuel, York, Ian, Gangappa, Shivaprakash, Sambhara, Suryaprakash, Mittal, Suresh K

“…The emergence of H5, H7, and H9 avian influenza virus subtypes in humans reveals their pandemic potential. Although human-to-human transmission has been…”
Get full text

MicroRNAs implicated in canine diffuse large B‐cell lymphoma prognosis by Elshafie, Nelly O., Gribskov, Michael, Lichti, Nathanael I., Sayedahmed, Ekramy E., Childress, Michael O., Pires dos Santos, Andrea

“…Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent subtype of non‐Hodgkin lymphoma (NHL) in domestic dogs, with many similarities to its human…”
Get full text

Adenoviral vector‐based platforms for developing effective vaccines to combat respiratory viral infections by Elkashif, Ahmed, Alhashimi, Marwa, Sayedahmed, Ekramy E, Sambhara, Suryaprakash, Mittal, Suresh K

“…Since the development of the first vaccine against smallpox over two centuries ago, vaccination strategies have been at the forefront of significantly…”
Get full text

Development of NP-Based Universal Vaccine for Influenza A Viruses by Sayedahmed, Ekramy E, Elshafie, Nelly O, Dos Santos, Andrea P, Jagannath, Chinnaswamy, Sambhara, Suryaprakash, Mittal, Suresh K

“…The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8 cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus…”
Get full text

Nested PCR Detection of Pythium sp. from Formalin-Fixed, Paraffin-Embedded Canine Tissue Sections by Elshafie, Nelly O., Hanlon, Jessica, Malkawi, Mays, Sayedahmed, Ekramy E., Guptill, Lynn F., Jones-Hall, Yava L., Santos, Andrea P.

“…Pythium insidiosum is an infectious oomycete affecting dogs that develop the cutaneous or gastrointestinal form of pythiosis with a poor prognosis. If left…”
Get full text

A Bovine Adenoviral Vector-Based H5N1 Influenza -Vaccine Provides Enhanced Immunogenicity and Protection at a Significantly Low Dose by Sayedahmed, Ekramy E., Hassan, Ahmed O., Kumari, Rashmi, Cao, Weiping, Gangappa, Shivaprakash, York, Ian, Sambhara, Suryaprakash, Mittal, Suresh K.

“…Several human and nonhuman adenovirus (AdV) vectors including bovine AdV type 3 (BAdV-3) were developed as gene delivery vectors to supplement and/or elude…”
Get full text

Current Use of Adenovirus Vectors and Their Production Methods by Sayedahmed, Ekramy E, Kumari, Rashmi, Mittal, Suresh K

“…Various adenovirus (AdV) vector systems have proven to be lucrative options for gene delivery. They can serve as potential vaccine candidates for prevention of…”
Get more information

The frequency and function of nucleoprotein-specific CD8 + T cells are critical for heterosubtypic immunity against influenza virus infection by Amoah, Samuel, Cao, Weiping, Sayedahmed, Ekramy E, Wang, Yuanyuan, Kumar, Amrita, Mishina, Margarita, Eddins, Devon J, Wang, Wen-Chien, Burroughs, Mark, Sheth, Mili, Lee, Justin, Shieh, Wun-Ju, Ray, Sean D, Bohannon, Caitlin D, Ranjan, Priya, Sharma, Suresh D, Hoehner, Jessica, Arthur, Robert A, Gangappa, Shivaprakash, Wakamatsu, Nobuko, Johnston, H Richard, Pohl, Jan, Mittal, Suresh K, Sambhara, Suryaprakash

“…Cytotoxic T lymphocytes (CTLs) mediate host defense against viral and intracellular bacterial infections and tumors. However, the magnitude of CTL response and…”
Get more information

A potential approach for assessing the quality of human and nonhuman adenoviral vector preparations by Sayedahmed, Ekramy E., Mittal, Suresh K.

“…Various types of human and nonhuman adenoviral (AdV) vectors are being used as gene delivery vectors in preclinical and clinical investigations. The objective…”
Get full text

Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy by Sayedahmed, Ekramy E., Kumari, Rashmi, Shukla, Shruti, Hassan, Ahmed O., Mohammed, Sulma I., York, Ian A., Gangappa, Shivaprakash, Sambhara, Suryaprakash, Mittal, Suresh K.

“…There is a high incidence of adenovirus (AdV) infection in humans due to the presence of more than 60 types of human adenoviruses (HAdVs). The majority of…”
Get full text

A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice by Khan, Arshad, Sayedahmed, Ekramy E., Singh, Vipul K., Mishra, Abhishek, Dorta-Estremera, Stephanie, Nookala, Sita, Canaday, David H., Chen, Min, Wang, Jin, Sastry, K. Jagannadha, Mittal, Suresh K., Jagannath, Chinnaswamy

“…Although the BCG vaccine offers partial protection, tuberculosis remains a leading cause of infectious disease death, killing ∼1.5 million people annually. We…”
Get full text

Micro RNA s implicated in canine diffuse large B‐cell lymphoma prognosis by Elshafie, Nelly O., Gribskov, Michael, Lichti, Nathanael I., Sayedahmed, Ekramy E., Childress, Michael O., Pires dos Santos, Andrea

“…Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent subtype of non‐Hodgkin lymphoma (NHL) in domestic dogs, with many similarities to its human…”
Get full text

Impact of an autophagy-inducing peptide on immunogenicity and protection efficacy of an adenovirus-vectored SARS-CoV-2 vaccine by Sayedahmed, Ekramy E., Araújo, Marcelo Valdemir, Silva-Pereira, Taiana Tainá, Chothe, Shubhada K., Elkashif, Ahmed, Alhashimi, Marwa, Wang, Wen-Chien, Santos, Andrea P., Nair, Meera Surendran, Gontu, Abhinay, Nissly, Ruth, Francisco de Souza Filho, Antônio, Tavares, Mariana Silva, Ayupe, Marina Caçador, Salgado, Caio Loureiro, Donizetti de Oliveira Candido, Érika, Leal Oliveira, Danielle Bruna, Durigon, Edison Luiz, Heinemann, Marcos Bryan, Morais da Fonseca, Denise, Jagannath, Chinnaswamy, Sá Guimarães, Ana Marcia, Kuchipudi, Suresh V., Mittal, Suresh K.

“…Because of continual generation of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is critical to design the next generation…”
Get full text