Search Results - "Sayed, Sinar"

Bilosomes as Promising Nanovesicular Carriers for Improved Transdermal Delivery: Construction, in vitro Optimization, ex vivo Permeation and in vivo Evaluation by Ahmed, Sadek, Kassem, Mohamed Aly, Sayed, Sinar

“…The goal of this research was to enhance the transdermal delivery of lornoxicam (LX), using nanovesicular carriers composed of the bile salt sodium…”
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Tailored nanostructured platforms for boosting transcorneal permeation: Box-Behnken statistical optimization, comprehensive in vitro, ex vivo and in vivo characterization by Elsayed, Ibrahim, Sayed, Sinar

“…Ocular drug delivery systems suffer from rapid drainage, intractable corneal permeation and short dosing intervals. Transcorneal drug permeation could increase…”
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A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration by Ahmed, Sadek, Amin, Maha M., Sayed, Sinar

“…This review aims to comprehensively highlight the recent nanosystems enclosing Fenticonazole nitrate (FTN) and to compare between them regarding preparation…”
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Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo assessments by Ahmed, Sadek, Amin, Maha M., El-Korany, Sarah Mohamed, Sayed, Sinar

“…The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-loaded novasomes aiming to enhance drug corneal penetration and to…”
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Cubogel as potential platform for glaucoma management by Sayed, Sinar, Abdel-Moteleb, Mostafa, Amin, Maha Mohamed, Khowessah, Omnia Mohamed

“…The aim of this work is to survey the potential of cubogel as an ocular dosage form to boost the corneal permeability of Dorzolamide Hydrochloride DZ; an…”
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Pronounced capping effect of olaminosomes as nanostructured platforms in ocular candidiasis management by Ahmed, Sadek, Amin, Maha M., El-Korany, Sarah Mohamed, Sayed, Sinar

“…The aim of this study was to formulate and boost ocular targeting of Fenticonazole Nitrate (FTN)-loaded olaminosomes in order to improve drug corneal…”
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Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m by Sayed, Sinar, Elsharkawy, Fatma M., Amin, Maha M., Shamsel-Din, Hesham A., Ibrahim, Ahmed B.

“…The research objective is to design intranasal (IN) brain targeted CLZ-loaded polymeric nanomicellar systems (PNMS) aiming to improve central systemic CLZ…”
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Ocular Drug Delivery: a Comprehensive Review by Ahmed, Sadek, Amin, Maha M., Sayed, Sinar

“…The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites. Effective…”
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Optimization of β-cyclodextrin consolidated micellar dispersion for promoting the transcorneal permeation of a practically insoluble drug by Sayed, Sinar, Elsayed, Ibrahim, Ismail, Maha M.

“…[Display omitted] Development of efficient ocular drug delivery system for antifungal drugs becomes a must nowadays to face and eradicate the widely spread…”
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Co-polymer mixed micelles enhanced transdermal transport of Lornoxicam: in vitro characterization, and in vivo assessment of anti-inflammatory effect and antinociceptive activity by Ahmed, Sadek, Kassem, Mohamed Aly, Sayed, Sinar

“…The objective of this study was to develop mixed micelles of Lornoxicam, using a Pluronic® mixture of L121 and P123. The technique used for the preparation was…”
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Enhanced transdermal delivery of ondansetron using nanovesicular systems: Fabrication, characterization, optimization and ex-vivo permeation study-Box-Cox transformation practical example by Habib, Basant A., Sayed, Sinar, Elsayed, Ghada M.

“…This study aimed to formulate suitable nanovesicles (NVs) for transdermal delivery of Ondansetron. It also illustrated a practical example for the importance…”
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Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and in vivo evaluation by Younes, Nihal Farid, Sayed, Sinar, Hassan, Mariam, Ahmed, Sadek

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Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and invivo evaluation by Younes, Nihal Farid, Sayed, Sinar, Hassan, Mariam, Ahmed, Sadek

“…Otitismedia is an acute illness that specifically targets the middle ear. It affects around one-third of the pediatric population in the US. This study aimed…”
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Enhanced skin targeting of retinoic acid spanlastics: in vitro characterization and clinical evaluation in acne patients by Shamma, Rehab Nabil, Sayed, Sinar, Sabry, Nirmeen Ahmed, El-Samanoudy, Solwan Ibrahim

“…Acne vulgaris is the most common dermatological disorder affecting millions of individuals. Acne therapeutic solutions include topical treatment with retinoic…”
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Effect of Formulation Variables and Gamma Sterilization on Transcorneal Permeation and Stability of Proniosomal Gels as Ocular Platforms for Antiglaucomal Drug by Sayed, Sinar, Abdelmoteleb, Mostafa, Amin, Maha M., Khowessah, Omnia M.

“…This study aims to evaluate the effect of different formulation variables (surfactant type and HLB value) adopting full factorial design (5 1 . 2 1 ) using…”
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Tri-block co-polymer nanocarriers for enhancement of oral delivery of felodipine: preparation, in vitro characterization and ex vivo permeation by Sayed, Sinar, Habib, Basant A., Elsayed, Ghada M.

“…This study aimed to prepare, optimize and characterize novel felodipine-loaded polymeric nanomicelles, using a pluronic mixture of F127 and P123. Thin-film…”
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Self-Assembling Lecithin-Based Mixed Polymeric Micelles for Nose to Brain Delivery of Clozapine: In-vivo Assessment of Drug Efficacy via Radiobiological Evaluation by M Elsharkawy, Fatma, M Amin, Maha, A Shamsel-Din, Hesham, Ibrahim, Walaa, Ibrahim, Ahmed B, Sayed, Sinar

“…The research objective is to design intranasal brain targeted CLZ loaded lecithin based polymeric micelles (CLZ- LbPM) aiming to improve central systemic CLZ…”
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