Search Results - "Saxena, Lovleen"
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Canine parvovirus NS1 induced apoptosis involves mitochondria, accumulation of reactive oxygen species and activation of caspases
Published in Virus research (02-02-2016)“…•Canine parvovirus NS1 (CPV2.NS1) protein does not activate extrinsic pathway of apoptosis.•Expression of CPV2.NS1 results in mitochondrial depolarization and…”
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Apoptosis induced by NS1 gene of Canine Parvovirus-2 is caspase dependent and p53 independent
Published in Virus research (01-05-2013)“…Apoptosis is programmed cell death that normally occurs during development and aging in multicellular animals. Apoptosis also occurs as a defense mechanism…”
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Velogenic Newcastle Disease Virus as an Oncolytic Virotherapeutics: In Vitro Characterization
Published in Applied biochemistry and biotechnology (01-08-2012)“…Cancer is one of the killer diseases in humans and needs alternate curative measures despite recent improvement in modern treatment modalities. Oncolytic…”
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Apoptin as a Potential Viral Gene Oncotherapeutic Agent
Published in Applied biochemistry and biotechnology (01-05-2015)“…The use of viruses for treatment of cancer overcomes the bottlenecks of chemotherapy and radiotherapy. Several viruses and their proteins have been evaluated…”
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Canine Parvovirus Type 2a (CPV-2a)-Induced Apoptosis in MDCK Involves Both Extrinsic and Intrinsic Pathways
Published in Applied biochemistry and biotechnology (2014)“…The canine parvovirus type 2 (CPV-2) causes an acute disease in dogs. It has been found to induce cell cycle arrest and DNA damage leading to cellular lysis…”
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In vitro expression studies of non structural 1 protein of Canine Parvo virus 2 by polyclonal antiserum raised against CPV2-NS1 protein expressed in Escherichia coli as an antigen
Published in Indian journal of experimental biology (01-09-2012)“…The canine Parvovirus 2, non-structural 1 (NS1) is a novel candidate tumor suppressor gene. To confirm the expression of the NS1 in HeLa cells after…”
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Development of dog mammary tumor xenograft in immunosuppressed Swiss albino mice
Published in Indian journal of experimental biology (01-10-2014)“…Development and study of dog mammary tumour xenograft in immunosuppressed Swiss Albino Mice adds a new dimension in cancer research as dog tumors have many…”
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Prokaryotic expression of chicken infectious anemia apoptin protein and characterization of its polyclonal antibodies
Published in Indian journal of experimental biology (01-05-2012)“…In the present study recombinant VP3 (rVP3) was expressed in E. coli BL21 (DE3) (pLysS) and its polyclonal antibodies were characterized. SDS-PAGE analysis…”
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Characterization and in vitro expression of non-structural 1 protein of canine parvovirus (CPV-2) in mammalian cell line
Published in Indian journal of experimental biology (01-09-2011)“…Parvoviruses are small, 260-A-diameter, icosahedral, non-enveloped, single-stranded DNA viruses with a genome of approximately 5 kb. Non structural protein,…”
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