Search Results - "Saxena, J.K"

Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: A behavioral, biochemical and cerebral blood flow study by Pachauri, Shakti Deep, Tota, Santoshkumar, Khandelwal, Kiran, Verma, P.R.P., Nath, Chandishwar, Hanif, Kashif, Shukla, Rakesh, Saxena, J.K., Dwivedi, Anil Kumar

“…Noni (Morinda citrifolia L.) is widely used for different illnesses including CNS disorders. Recently Noni has been reported to prevent amyloid beta induced…”
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Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores by Sashidhara, Koneni V., Kumar, Manoj, Modukuri, Ram K., Srivastava, Rajeev Kumar, Soni, Awakash, Srivastava, Kumkum, Singh, Shiv Vardan, Saxena, J.K., Gauniyal, Harsh M., Puri, Sunil K.

“…Synthesis and antimalarial evaluation of novel chalcone-chloroquine hybrids is reported. A series of novel keto-enamine chalcone-chloroquine based hybrids were…”
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Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials by Sunduru, Naresh, Srivastava, Kumkum, Rajakumar, S., Puri, S.K., Saxena, J.K., Chauhan, Prem M.S.

“…New prototypes of thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline were synthesized and screened for their antimalarial…”
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Ketoconazole, a cytochrome P450 inhibitor can potentiate the antimalarial action of α/β arteether against MDR Plasmodium yoelii nigeriensis by Tripathi, Renu, Rizvi, Amber, Pandey, Swaroop Kumar, Dwivedi, Hemlata, Saxena, J.K.

“…A combination of ketoconazole with α/β arteether has shown to exhibit concentration dependent antimalarial activity in vitro against Plasmodium falciparum as…”
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Implication of intracellular glutathione and its related enzymes on resistance of malaria parasites to the antimalarial drug arteether by Chandra, Ramesh, Tripathi, L.M, Saxena, J.K, Puri, S.K

“…Abstract The control of malaria has been complicated by the increasing resistance of malarial parasites to multiple drugs. However, artemisinin-based drugs…”
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Sensitization with anti-inflammatory BmAFI of Brugia malayi allows L3 development in the hostile peritoneal cavity of Mastomys coucha by Joseph, S.K., Verma, S.K., Sahoo, M.K., Dixit, S., Verma, A.K., Kushwaha, V., Saxena, K., Sharma, A., Saxena, J.K., Murthy, P.K.

“…Sensitization with BmAFI which shares some molecules with L3, generates anti-inflammatory milieu and modified Th2 response and facilitates development of…”
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Synthesis and bioevaluation of novel 4-aminoquinoline-tetrazole derivatives as potent antimalarial agents by Pandey, Shashi, Agarwal, Pooja, Srivastava, Kumkum, RajaKumar, S., Puri, Sunil K., Verma, Pravesh, Saxena, J.K., Sharma, Abhisheak, Lal, Jawahar, Chauhan, Prem M.S.

“…A series of novel tetrazole derivatives of 4-aminoquinoline were synthesized and screened for their antimalarial activities against both chloroquine-senstive…”
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Isolation and identification of β-hematin inhibitors from Flacourtia indica as promising antiplasmodial agents by Sashidhara, Koneni V., Singh, Suriya P., Singh, Shiv Vardan, Srivastava, Rajeev K., Srivastava, Kumkum, Saxena, J.K., Puri, Sunil K.

“…An ethanolic extract (A001) of the leaves and twigs of Flacourtia indica (Burm.f.) Merr., was purified to give a new phenolic glycoside,…”
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Synthesis and biological evaluation of a new class of 4-aminoquinoline-rhodanine hybrid as potent anti-infective agents by Chauhan, Kuldeep, Sharma, Moni, Saxena, Juhi, Singh, Shiv Vardan, Trivedi, Priyanka, Srivastava, Kumkum, Puri, Sunil K, Saxena, J K, Chaturvedi, Vinita, Chauhan, Prem M S

“…Synthesis of novel 4-aminoquinoline-rhodanine hybrid using inexpensive starting materials via easy to operate methodology, and their biological activity is…”
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Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents by SASHIDHARA, Koneni V, ROSAIAH, Jammikuntla N, BHATIA, Gitika, SAXENA, J. K

“…A series of Schiff bases have been synthesized from dicarbaldehyde of benzocoumarin, in which the reactions were regioselective and the products existed in the…”
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Synthesis and in vitro evaluation of new chloroquine-chalcone hybrids against chloroquine-resistant strain of Plasmodium falciparum by Sashidhara, Koneni V., Avula, Srinivasa Rao, Palnati, Gopala Reddy, Singh, Shiv Vardan, Srivastava, Kumkum, Puri, Sunil K., Saxena, J.K.

“…A bioinspired hybrid molecular approach to combat chloroquine resistance. The control of malaria has been complicated with increasing resistance of malarial…”
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Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity by Sunduru, Naresh, Sharma, Moni, Srivastava, Kumkum, Rajakumar, S., Puri, S.K., Saxena, J.K., Chauhan, Prem M.S.

“…In search of novel 4-aminoquinolines to counteract the problem of resistance, side chain incorporated oxalamide and triazine derivatives were synthesized and…”
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Synthesis, molecular docking and Brugia malayi thymidylate kinase (BmTMK) enzyme inhibition study of novel derivatives of [6]-shogaol by Singh, Vinay Kr, Doharey, Pawan K., Kumar, Vikash, Saxena, J.K., Siddiqi, M.I., Rathaur, Sushma, Narender, Tadigoppula

“…[6]-Shogaol (1) was isolated from Zingiber officinale. Twelve novel compounds have been synthesized and evaluated for their Brugia malayi thymidylate kinase…”
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Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases by SASHIDHARA, Koneni V, KUMAR, Abdhesh, BHATIA, Gitika, KHAN, M. M, KHANNA, A. K, SAXENA, J. K

“…8-Hydroxyquinoline when subjected to Duff reaction resulted in the formation of unexpected 7-methylaminomethylene-8-oxo-7, 8-dihydroquinoline-5-carbaldehyde 2,…”
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Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2 H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents by Sashidhara, Koneni V., Rosaiah, Jammikuntla N., Bhatia, Gitika, Saxena, J.K.

“…A series of Schiff bases have been synthesized from dicarbaldehyde of benzocoumarin, in which the reactions were regioselective and the products existed in the…”
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Potential inhibitors of DNA topoisomerase II: ruthenium(II) poly-pyridyl and pyridyl-azine complexes by Chandra, Manish, Sahay, A.N., Pandey, D.S., Tripathi, R.P., Saxena, J.K., Reddy, V.J.M., Carmen Puerta, M., Valerga, Pedro

“…Mono and binuclear cationic complexes with their respective formulation [RuH(CO)(PPh 3) 2(L)] + and [{RuH(CO)(PPh 3) 2} 2(μ-L)] 2+ [where…”
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Syntheses of 2,4,6-trisubstituted pyrimidine derivatives as a new class of antifilarial topoisomerase II inhibitors by Katiyar, Sanjay Babu, Bansal, Iti, Saxena, J.K., Chauhan, P.M.S.

“…A series of 21 compounds of trisubstituted pyrimidine derivatives have been synthesized and evaluated for their in vitro topoisomerase II inhibitory activity…”
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Polyamine metabolism in some helminth parasites by Sharma, V, Tekwani, B L, Saxena, J K, Gupta, S, Katiyar, J C, Chatterjee, R K, Ghatak, S, Shukla, O P

“…Polyamine levels of some helminth parasites were analyzed by reverse phase HPLC of benzoyl derivatives. Setaria cervi, Acanthocheilonema viteae, Hymenolepis…”
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Pregnane glycoside from Hemidesmus indicus as a potential anti-oxidant and anti-dyslipidemic agent by Sethi, Arun, Bhatia, Akriti, Srivastava, Sanjay, Bhatia, Geetika, Khan, M.M., Khanna, A.K., Saxena, J.K.

“…A new pregnane glycoside hindicusine (1) was isolated from the CHCl 3 -EtOH (3 : 2) extract of Hemidesmus indicus, whose structure was established on the basis…”
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Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents by Sethi, Arun, Maurya, Atul, Tewari, Vibha, Srivastava, Sanjay, Faridi, Shaheen, Bhatia, Gitika, Khan, M.M., Khanna, A.K., Saxena, J.K.

“…Expeditious and convenient procedures for the synthesis of newer pregnane derivatives and its glycosides are reported. Amongst them compound 3 and 7 showed…”
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