Search Results - "Saxby, Brian K"

Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial by Ballard, Clive, Jones, Emma, Gauge, Nathan, Aarsland, Dag, Nilsen, Odd Bjarte, Saxby, Brian K, Lowery, David, Corbett, Anne, Wesnes, Keith, Katsaiti, Eirini, Arden, James, Amoako, Derek, Amaoko, Derek, Prophet, Nicholas, Purushothaman, Balaji, Green, David

“…The study determined the one year incidence of post operative cognitive decline (POCD) and evaluated the effectiveness of an intra-operative anaesthetic…”
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Longitudinal investigation of the factor structure of the Parkinson's disease activities of daily living, interference and dependence instrument by Sirbu, Cristian, Saxby, Brian K., McNamara, Cynthia W., Deal, Linda S.

“…The Parkinson's Disease Activities of Daily Living, Interference, and Dependence Instrument© (PD-AID) is a patient-reported outcome (PRO) instrument, recently…”
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Relationship Between Cognition, Magnetic Resonance White Matter Hyperintensities, and Cardiovascular Autonomic Changes in Late-Life Depression by Vasudev, Akshya, Ph.D, Saxby, Brian K., Ph.D, O'Brien, John T., F.R.C.Psych., D.M, Colloby, Sean J., Ph.D, Firbank, Michael J., Ph.D, Brooker, Helen, Ph.D, Wesnes, Keith, Ph.D, Thomas, Alan J., Ph.D., M.R.C.Psych

“…Objectives To explore the relationship between specific aspects of cognition, white matter hyperintensities (WMHs), and cardiovascular autonomic parameters in…”
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Longitudinal changes in global and domain specific cognitive function in the very‐old: findings from the Newcastle 85+ Study by Stephan, Blossom C. M., Muniz‐Terrera, Graciela, Granic, Antoneta, Collerton, Joanna, Davies, Karen, Saxby, Brian K., Wesnes, Keith A., Kirkwood, Thomas B.L., Jagger, Carol

“…Objective Ageing is associated with changes in cognition in some, but not all domains. In young–old adults, defined as persons aged 65–84 years, baseline…”
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The effect of passive heating and head cooling on perception, cardiovascular function and cognitive performance in the heat by Simmons, Shona E., Saxby, Brian K., McGlone, Francis P., Jones, David A.

“…The present study examined the effects of raising both skin temperature and core temperature, separately and in combination, on perceptions of heat-related…”
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A Comparison of Computerized and Pencil-and-Paper Tasks in Assessing Cognitive Function in Community-Dwelling Older People in the Newcastle 85+ Pilot Study by Collerton, Joanna, Collerton, Daniel, Arai, Yasumichi, Barrass, Karen, Eccles, Martin, Jagger, Carol, McKeith, Ian, Saxby, Brian K, Kirkwood, Tom

“…OBJECTIVES: To compare the acceptability and feasibility of computerized and pencil‐and‐paper tests of cognitive function in 85‐year‐old people. DESIGN: Group…”
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Poststroke Urinary Incontinence: One-Year Outcome and Relationships with Measures of Attentiveness by Pettersen, Renate, Saxby, Brian K., Wyller, Torgeir Bruun

“…OBJECTIVES: To investigate the prognostic effect of poststroke urinary incontinence (UI) on 1‐year outcome in relation to measurements of attention and mental…”
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Cognitive Performance in Hypertensive and Normotensive Older Subjects by Harrington, Frances, Saxby, Brian K, McKeith, Ian G, Wesnes, Keith, Ford, Gary A

“…Longitudinal studies suggest that hypertension in midlife is associated with cognitive impairment in later life. Cross-sectional studies are difficult to…”
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Correction: Optimised Anaesthesia to Reduce Post Operative Cognitive Decline (POCD) in Older Patients Undergoing Elective Surgery, a Randomised Controlled Trial by Ballard, Clive, Jones, Emma, Gauge, Nathan, Aarsland, Dag, Nilsen, Odd Bjarte, Saxby, Brian K., Lowery, David, Corbett, Anne, Wesnes, Keith, Katsaiti, Eirini, Arden, James, Amaoko, Derek, Prophet, Nicholas, Purushothaman, Balaji, Green, David

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Effects of Hypertension on Attention, Memory, and Executive Function in Older Adults by Saxby, Brian K, Harrington, Frances, McKeith, Ian G, Wesnes, Keith, Ford, Gary A

“…Hypertension is associated with impairments in cognitive function in older adults, but the nature and extent of these deficits are unclear. Brief cognitive…”
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Correction: Optimised Anaesthesia to Reduce Post Operative Cognitive Decline (POCD) in Older Patients Undergoing Elective Surgery, a Randomised Controlled Trial by Ballard, Clive, Jones, Emma, Gauge, Nathan, Aarsland, Dag, Nilsen, Odd Bjarte, Saxby, Brian K., Lowery, David, Corbett, Anne, Wesnes, Keith, Katsaiti, Eirini, Arden, James, Amoako, Derek, Prophet, Nicholas, Purushothaman, Balaji, Green, David

“…(2012) Correction: Optimised Anaesthesia to Reduce Post Operative Cognitive Decline (POCD) in Older Patients Undergoing Elective Surgery, a Randomised…”
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A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects by Holloway, Cameron J, Cochlin, Lowri E, Emmanuel, Yaso, Murray, Andrew, Codreanu, Ion, Edwards, Lindsay M, Szmigielski, Cezary, Tyler, Damian J, Knight, Nicholas S, Saxby, Brian K, Lambert, Bridget, Thompson, Campbell, Neubauer, Stefan, Clarke, Kieran

“…Background: High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free…”
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Computerized Psychometric Testing in Minimal Encephalopathy and Modulation by Nitrogen Challenge and Liver Transplant by Mardini, Hanan, Saxby, Brian K, Record, Christopher O

“…Background & Aims A lack of standardized tests was cited by hepatologists for not testing for minimal hepatic encephalopathy. We therefore compared paper and…”
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Testosterone and mood dysfunction in women with polycystic ovarian syndrome compared to subfertile controls by Barry, John A., Hardiman, Paul J., Saxby, Brian K., Kuczmierczyk, Andrew

“…Women with polycystic ovarian syndrome (PCOS) have been found to suffer from fertility problems and mood dysfunction. To control for any effect of fertility…”
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Brain atrophy and white matter hyperintensity change in older adults and relationship to blood pressure : Brain atrophy, WMH change and blood pressure by FIRBANK, Michael J, WISEMAN, Rebecca M, BURTON, Emma J, SAXBY, Brian K, O'BRIEN, John T, FORD, Gary A

“…Hypertension is a major risk factor for stroke and dementia and is associated with white matter hyperintensities (WMH) and reduced brain volumes. We measured…”
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Year-by-year cognitive decline in non-demented elderly aged 70 to 90 years by Wesnes, Keith, Saxby, Brian K, Ford, Gary

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Homocysteine is associated with hippocampal and white matter atrophy in older subjects with mild hypertension by Firbank, Michael J, Narayan, Sunil K, Saxby, Brian K, Ford, Gary A, O'Brien, John T

“…Plasma homocysteine has been associated with reduced brain volumes in cross-sectional studies. We aimed to investigate if homocysteine is associated with…”
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Quantitative magnetic resonance imaging in patients with cirrhosis: a cross-sectional study by Grover, Vijay P. B., Crossey, Mary M. E., Fitzpatrick, Julie A., Saxby, Brian K., Shaw, Roberta, Waldman, Adam D., Morgan, Marsha Y., Taylor-Robinson, Simon D.

“…Cerebral magnetic resonance imaging was undertaken, at 3 Tesla field strength, employing magnetization transfer (MT) and diffusion-weighted imaging (DWI)…”
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Modulation of neural activation following treatment of hepatic encephalopathy by MCPHAIL, Mark J. W, LEECH, Robert, WALDMAN, Adam D, THOMAS, Howard C, TAYLOR-ROBINSON, Simon D, GROVER, Vijay P. B, FITZPATRICK, Julie A, DHANJAL, Novraj S, CROSSEY, Mary M. E, PFLUGRAD, Henning, SAXBY, Brian K, WESNES, Keith, DRESNER, M. Alex

“…To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic…”
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Elevated plasma homocysteine is associated with increased brain atrophy rates in older subjects with mild hypertension by Narayan, Sunil K, Firbank, Michael J, Saxby, Brian K, Stansby, Gerard, Hansrani, Monica, O'Brien, John T, Ford, Gary A

“…We determined using serial MR imaging whether raised plasma homocysteine levels are associated with increased brain atrophy, white matter lesion (WML)…”
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