Search Results - "Sax, CM"

The cellular basis of corneal transparency: evidence for 'corneal crystallins' by Jester, J V, Moller-Pedersen, T, Huang, J, Sax, C M, Kays, W T, Cavangh, H D, Petroll, W M, Piatigorsky, J

“…In vivo corneal light scattering measurements using a novel confocal microscope demonstrated greatly increased backscatter from corneal stromal fibrocytes…”
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A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins by Cvekl, A, Sax, C M, Bresnick, E H, Piatigorsky, J

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Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene by Cvekl, A, Sax, C M, Li, X, McDermott, J B, Piatigorsky, J

“…The abundance of delta-crystallin in the chicken eye lens provides an advantageous marker for tissue-specific gene expression during cellular differentiation…”
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Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site by Cvekl, Aleš, Kashanchi, Fatah, Sax, Christina M., Brady, John N., Piatigorsky, Joram

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Transketolase Is a Major Protein in the Mouse Cornea by Sax, Christina M., Salamon, Csaba, Kays, W. Todd, Guo, Jing, Yu, Fushin X., Cuthbertson, R. Andrew, Piatigorsky, Joram

“…Earlier experiments in this laboratory identified a highly expressed 65-68-kDa protein in both mouse and human corneas (Cuthbertson, R. A., Tomarev, S. I., and…”
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Regulation of alpha A-crystallin Gene Expression: Lens Specificity Achieved Through the Differential Placement of Similar Transcriptional Control Elements in Mouse and Chicken by Ilagan, J G, Cvekl, A, Kantorow, M, Piatigorsky, J, Sax, C M

“…The lens-preferred mouse alpha A-crystallin gene contains a conserved stretch (proximal element 2, +24/+43) in its 5'-noncoding region that we have previously…”
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Transketolase Gene Expression in the Cornea Is Influenced by Environmental Factors and Developmentally Controlled Events by Sax, Christina M, Kays, W Todd, Salamon, Csaba, Chervenak, Matthew M, Xu, Yong-Sheng, Piatigorsky, Joram

“…PURPOSE.Transketolase (TKT) has been proposed to be a corneal crystallin, and its gene and protein are abundantly expressed in the corneal epithelium of…”
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The Mouse Transketolase (TKT) Gene: Cloning, Characterization, and Functional Promoter Analysis by Salamon, Csaba, Chervenak, Matthew, Piatigorsky, Joram, Sax, Christina M.

“…The transketolase (TKT) gene is expressed 30–50 times more highly in the mature mouse cornea than in other tissues. Here, we have cloned and characterized the…”
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Expression of Crystallins, Pax6, Filensin, CP49, MIP, and MP20 in lens- derived cell lines by Krausz, E, Augusteyn, RC, Quinlan, RA, Reddan, JR, Russell, P, Sax, CM, Graw, J

“…Cell lines are the systems of choice to analyze cellular functions related to the particular organ system. For lens research, three cell lines are widely used:…”
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Transcriptional regulation of the mouse αA-crystallin gene: binding of USF to the −7/+5 region by Sax, Christina M., Cvekl, Ales, Piatigorsky, Joram

“…Lens preferred-expression of the mouse αA-crystallin gene (αA- cry) is regulated at the transcriptional level by multiple elements located in the 5′ flanking…”
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Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes by NAKAMURA, T, DONOVAN, D. M, HAMADA, K, SAX, C. M, NORMAN, B, FLANAGAN, J. R, OZATO, K, WESTPHAL, H, PIATIGORSKY, J

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Sequence, initial functional analysis and protein-DNA binding sites of the mouse βB2-crystallin-encoding gene by Chambers, Carolyn, Cvekl, Ales, Sax, Christina M., Russell, Paul

“…An 800-bp fragment of genomic DNA upstream from the origin of transcription of the mouse βB2-crystallin-encoding gene ( βB2-Cry) has been isolated and its…”
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Murine transcription factor alpha A-crystallin binding protein I. Complete sequence, gene structure, expression, and functional inhibition via antisense RNA by Brady, J P, Kantorow, M, Sax, C M, Donovan, D M, Piatigorsky, J

“…alpha A-crystallin binding protein I (alpha A-CRYBP1) is a ubiquitously expressed DNA binding protein that was previously identified by its ability to interact…”
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Heterogeneous expression of transketolase in ocular tissues by Guo, Jing, Sax, Christina M., Piatigorsky, Joram, Yu, Fushin X.

“…PURPOSE. Previous studies have shown that transketolase is preferentially expressed in the corneal epithelium and comprises up to 10% of the soluble protein of…”
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A negative element involved in vimentin gene expression by FARRELL, F. X, SAX, C. M, ZEHNER, Z. E

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Functional redundancy of the DE-1 and αA-CRYBP1 regulatory sites of the mouse αA-crystallin promoter by Sax, Christina M., Iiagan, John G., Piatigorsky, Joram

“…Previous studies have implicated the DE-1 (−111/−106) and αA-CRYBP1 (−66/−57) sites for activity of the mouse αA-crystallin promoter in transiently transfected…”
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Lens-specific activity of the mouse αA-crystallin promoter in the absence of a TATA box: functional and protein binding analysis of the mouse (αA-crystallin PE1 region by Sax, Christina M., Cvekl, Ales, Kantorow, Marc, Gopal-Srivastava, Rashmi, Ilagan, John G., Ambulos, Nicholas P., Piatigorsky, Joram

“…Lens-specific expression of the mouse αA-crystallin gene is regulated at the level of transcription. Here, we have studied the role of the PE1 region, which…”
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Analysis of α-crystallin expression in cultured mouse and rabbit lens cells by Sax, Christina M., Dziedzic, Dorothy C., Piatigorsky, Joram, Reddan, John R.

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Regulation of vimentin gene expression in the ocular lens by Sax, Christina M., Farrell, Francis X., Zehner, Zendra E., Piatigorsky, Joram

“…Vimentin expression in the lens is striking due to the reported mesenchymal preference of vimentin and the epithelial origin of the lens. The amount of chicken…”
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Identification of negative-acting and protein-binding elements in the mouse alpha A-crystallin -1556/-1165 region by Sax, C M, Cvekl, A, Kantorow, M, Sommer, B, Chepelinsky, A B, Piatigorsky, J

“…The mouse alpha A-crystallin-encoding gene (alpha A-cry) is expressed in a highly lens-preferred manner. To date, it has been shown that this lens-preferred…”
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