Search Results - "Sawyer, Travis"

Ovarian cancer detection using optical coherence tomography and convolutional neural networks by Schwartz, David, Sawyer, Travis W., Thurston, Noah, Barton, Jennifer, Ditzler, Gregory

“…Ovarian cancer has the sixth-largest fatality rate in the United States among all cancers. A non-surgical assay capable of detecting ovarian cancer with…”
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Combined flat-field and frequency filter approach to correcting artifacts of multichannel two-photon microscopy by Knapp, Thomas, Lima, Natzem, Daigle, Noelle, Duan, Suzann, Merchant, Juanita L., Sawyer, Travis W.

“…Multiphoton microscopy (MPM) is a useful biomedical imaging tool for its ability to probe labeled and unlabeled depth-resolved tissue biomarkers at high…”
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Opti-MSFA: a toolbox for generalized design and optimization of multispectral filter arrays by Sawyer, Travis W, Taylor-Williams, Michaela, Tao, Ran, Xia, Ruqiao, Williams, Calum, Bohndiek, Sarah E

“…Multispectral imaging captures spatial information across a set of discrete spectral channels and is widely utilized across diverse applications such as remote…”
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Spatial profiling reveals tissue‐specific neuro‐immune interactions in gastroenteropancreatic neuroendocrine tumors by Duan, Suzann, Sawyer, Travis W, Witten, Brandon L, Song, Heyu, Else, Tobias, Merchant, Juanita L

“…Gastroenteropancreatic neuroendocrine tumors (GEP‐NETs) are heterogeneous malignancies that arise from complex cellular interactions within the tissue…”
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Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging by Bonaventura, Justina, Morara, Kellys, Carlson, Rhea, Comrie, Courtney, Twer, AnneLeigh, Hutchinson, Elizabeth, Sawyer, Travis W.

“…Knowledge of fiber microstructure and orientation in the brain is critical for many applications. Polarized light imaging (PLI) has been shown to have…”
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Quantitative characterization of duodenal gastrinoma autofluorescence using multiphoton microscopy by Knapp, Thomas G., Duan, Suzann, Merchant, Juanita L., Sawyer, Travis W.

“…Background Duodenal gastrinomas (DGASTs) are neuroendocrine tumors that develop in the submucosa of the duodenum and produce the hormone gastrin. Surgical…”
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Targeted multispectral filter array design for the optimization of endoscopic cancer detection in the gastrointestinal tract by Taylor-Williams, Michaela, Tao, Ran, Sawyer, Travis W., Waterhouse, Dale J., Yoon, Jonghee, Bohndiek, Sarah E.

“…Color differences between healthy and diseased tissue in the gastrointestinal (GI) tract are detected visually by clinicians during white light endoscopy;…”
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Wide field-of-view fluorescence imaging for organ-level lineage tracing of rare intestinal stem cell populations by Daigle, Noelle, Duan, Suzann, Song, Heyu, Lima, Natzem, Sontz, Ricky, Merchant, Juanita L., Sawyer, Travis W.

“…Lineage tracing using fluorescent reporters is a common tool for monitoring the expression of genes and transcription factors in stem cell populations and…”
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Multispectral imaging of nailfold capillaries using light-emitting diode illumination by Taylor-Williams, Michaela, Mead, Stephen, Sawyer, Travis W., Hacker, Lina, Williams, Calum, Berks, Michael, Murray, Andrea, Bohndiek, Sarah E.

“…The capillaries are the smallest blood vessels in the body, typically imaged using video capillaroscopy to aid diagnosis of connective tissue diseases, such as…”
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Three-dimensional texture analysis of optical coherence tomography images of ovarian tissue by Sawyer, Travis W, Chandra, Swati, Rice, Photini F S, Koevary, Jennifer W, Barton, Jennifer K

“…Ovarian cancer has the lowest survival rate among all gynecologic cancers due to predominantly late diagnosis. Optical coherence tomography (OCT) has been…”
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Quantification of multiphoton and fluorescence images of reproductive tissues from a mouse ovarian cancer model shows promise for early disease detection by Sawyer, Travis W, Koevary, Jennifer W, Rice, Faith P. S, Howard, Caitlin C, Austin, Olivia J, Connolly, Denise C, Cai, Kathy Q, Barton, Jennifer K

“…Ovarian cancer is the deadliest gynecologic cancer due predominantly to late diagnosis. Early detection of ovarian cancer can increase 5-year survival rates…”
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Fluorescence and Multiphoton Imaging for Tissue Characterization of a Model of Postmenopausal Ovarian Cancer by Sawyer, Travis W., Koevary, Jennifer W., Howard, Caitlin C., Austin, Olivia J., Rice, Photini F. S., Hutchens, Gabrielle V., Chambers, Setsuko K., Connolly, Denise C., Barton, Jennifer K.

“…Background and Objectives To determine the efficacy of targeted fluorescent biomarkers and multiphoton imaging to characterize early changes in ovarian tissue…”
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GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming by Duan, Suzann, Sawyer, Travis W., Sontz, Ricky A., Wieland, Bradley A., Diaz, Andres F., Merchant, Juanita L.

“…Efforts to characterize the signaling mechanisms that underlie gastroenteropancreatic neoplasms (GEP-NENs) are precluded by a lack of comprehensive models that…”
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Design, fabrication, and preclinical testing of a miniaturized, multispectral, chip-on-tip, imaging probe for intraluminal fluorescence imaging of the gastrointestinal tract by Slomka, Bridget, Duan, Suzann, Knapp, Thomas G, Lima, Natzem, Sontz, Ricky, Merchant, Juanita L, Sawyer, Travis W

“…Gastrointestinal cancers continue to account for a disproportionately large percentage of annual cancer deaths in the US. Advancements in miniature imaging…”
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Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover by Duan, Suzann, Sheriff, Sulaiman, Elvis-Offiah, Uloma B, Witten, Brandon L, Sawyer, Travis W, Sundaresan, Sinju, Cierpicki, Tomasz, Grembecka, Jolanta, Merchant, Juanita L

“…Loss of the tumor suppressor protein menin is a critical event underlying the formation of neuroendocrine tumors (NET) in hormone-expressing tissues including…”
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Pilot Study: Texture Analysis of PET Imaging Demonstrates Changes in 18 F-FDG Uptake of the Brain After Prophylactic Cranial Irradiation by Sawyer, David M, Sawyer, Travis W, Eshghi, Naghmehossadat, Hsu, Charles, Hamilton, Russell J, Garland, Linda L, Kuo, Phillip H

“…Prophylactic cranial irradiation (PCI) is used to decrease the probability of developing brain metastases in patients with small cell lung cancer and has been…”
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Evaluation of segmentation algorithms for optical coherence tomography images of ovarian tissue by Sawyer, Travis W, Rice, Photini F S, Sawyer, David M, Koevary, Jennifer W, Barton, Jennifer K

“…Ovarian cancer has the lowest survival rate among all gynecologic cancers predominantly due to late diagnosis. Early detection of ovarian cancer can increase…”
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Sa1936 MEASURING THE HYPERSPECTRAL AND AUTO-FLUORESCENT SIGNATURE OF ESOPHAGEAL CANCER FOR EVALUATING DIAGNOSTIC OPTICAL IMAGING BIOMARKERS USING EX-VIVO CLINICAL SPECIMENS by Lima, Natzem, Alameri, Aws, Banerjee, Bhaskar, Gavini, Hemanth K., Sawyer, Travis W.

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213: GFAP-DIRECTED INACTIVATION OF MEN1 PROMOTES NEUROENDOCRINE DIFFERENTIATION BY EXPLOITING GLIAL CELL PLASTICITY by Duan, Suzann, Sawyer, Travis W., Sontz, Ricky, Wieland, Bradley, Diaz, Andres F., Merchant, Juanita L.

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Su1659: DEMONSTRATING WHOLE-ORGAN LINEAGE TRACING OF FLUORESCENT MARKERS IN INTESTINAL STEM CELLS USING WIDEFIELD FLUORESCENCE IMAGING IN A ZFP148CREERT2 MOUSE MODEL by Daigle, Noelle, Song, Heyu, Sontz, Ricky, Merchant, Juanita L., Sawyer, Travis W.

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