Search Results - "Sawyer, Lynette"

Photochemical treatment of plasma with amotosalen and long-wavelength ultraviolet light inactivates pathogens while retaining coagulation function by Singh, Yasmin, Sawyer, Lynette S., Pinkoski, Linda S., Dupuis, Kent W., Hsu, Jocelyn C., Lin, Lily, Corash, Laurence

“…BACKGROUND:  The INTERCEPT Blood System, a photochemical treatment (PCT) process, has been developed to inactivate pathogens in platelet concen‐trates. These…”
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Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody by Burton, Dennis R., Pyati, Jayashree, Koduri, Raju, Sharp, Stephen J., Thornton, George B., Paul W. H. I. Parren, Lynette S. W. Sawyer, Hendry, R. Michael, Dunlop, Nancy, Nara, Peter L., Lamacchia, Michael, Garratty, Eileen, Stiehm, E. Richard, Bryson, Yvonne J., Cao, Yunzhen, Moore, John P., Ho, David D., Barbas, Carlos F.

“…The ability of antibodies to neutralize diverse primary isolates of human immunodeficiency virus-type 1 in vitro has been questioned, with implications for the…”
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Amotosalen and UVA Light Inactivate Enterococcus Faecalis, Serratia Liquefaciens, and Multiple Species of Streptococcus in Platelet Components by Green, Jennifer, PhD, Hanson, Debbie, Patel, Nidhi, Goldbeck, Kelsey, Sawyer, Lynette, PharmD

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Postexposure Immunoprophylaxis of Primary Isolates by an Antibody to HIV Receptor Complex by Wang, Chang Yi, Lynette S. W. Sawyer, Murthy, Krishna K., Fang, Xinde, Walfield, Alan M., Ye, John, James J. G. Wang, De Chen, Pei, Li, Ming Lie, Salas, Mary T., Shen, Ming, Gauduin, Marie-Claire, Boyle, Rosanne W., Koup, Richard A., Montefiori, David C., Mascola, John R., Koff, Wayne C., Hanson, Carl V.

“…mAb B4 is a monoclonal antibody directed against HIV receptor complex. The antibody had broad neutralizing activity against HIV and provided postexposure…”
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Photochemical inactivation of chikungunya virus in human apheresis platelet components by amotosalen and UVA light by Tsetsarkin, Konstantin A, Sampson-Johannes, Adam, Sawyer, Lynette, Kinsey, John, Higgs, Stephen, Vanlandingham, Dana L

“…Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in Africa and rapidly spread into countries of the Indian Ocean basin and…”
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Photochemical inactivation with amotosalen and long-wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components by Grellier, Philippe, Benach, Jorge, Labaied, Mehdi, Charneau, Sébastien, Gil, Horacio, Monsalve, Gloria, Alfonso, Ryan, Sawyer, Lynette, Lin, Lily, Steiert, Matthias, Dupuis, Kent

“…BACKGROUND: Transfusion‐transmitted cases of malaria and babesiosis have been well documented. Current efforts to screen out contaminated blood products result…”
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Inactivation of parvovirus B19 in human platelet concentrates by treatment with amotosalen and ultraviolet A illumination by Sawyer, Lynette, Hanson, Deborah, Castro, Grace, Luckett, William, Dubensky Jr, Thomas W., Stassinopoulos, Adonis

“…BACKGROUND: The human erythrovirus B19 (B19) is a small (18‐ to 26‐nm) nonenveloped virus with a single‐stranded DNA genome of 5.6 kb. B19 is clinically…”
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BLOOD COMPONENTS: Photochemical treatment of plasma with amotosalen and long-wavelength ultraviolet light inactivates pathogens while retaining coagulation function by Singh, Yasmin, Sawyer, Lynette S, Pinkoski, Linda S, Dupuis, Kent W, Hsu, Jocelyn C, Lin, Lily, Corash, Laurence

“…BACKGROUND:The INTERCEPT Blood System, a photochemical treatment (PCT) process, has been developed to inactivate pathogens in platelet concen-trates. These…”
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Multicenter evaluation of the Bayer VERSANT™ HIV-1 RNA 3.0 assay: analytical and clinical performance by Gleaves, Curt A., Welle, John, Campbell, Mary, Elbeik, Tarek, Ng, Valerie, Taylor, Patricia E., Kuramoto, Ken, Aceituno, Sherri, Lewalski, Eva, Joppa, Barbara, Sawyer, Lynette, Schaper, Carl, McNairn, Denise, Quinn, Thomas

“…Background: The use of quantitative HIV-1 RNA assays is part of the standard of care for the management of HIV-1-infected individuals. Objective: The Bayer…”
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In vitro Evolution of a Neutralizing Human Antibody to Human Immunodeficiency Virus Type 1 to Enhance Affinity and Broaden Strain Cross-Reactivity by Barbas, Carlos F., Hu, Dana, Dunlop, Nancy, Sawyer, Lynette, Cababa, Doug, Hendry, R. Michael, Nara, Peter L., Burton, Dennis R.

“…A method is described that allows for the improvement of antibody affinity. This method, termed complementary-determining region (CDR) walking, does not…”
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Neutralization sensitivity of human immunodeficiency virus type 1 is determined in part by the cell in which the virus is propagated by SAWYER, L. S. W, WRIN, M. T, CRAWFORD-MIKSZA, L, POTTS, B, YAMING WU, WEBER, P. A, ALFONSO, R. D, HANSON, C. V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Passive Infusion of Immune Serum into Simian Immunodeficiency Virus-Infected Rhesus Macaques Undergoing a Rapid Disease Course Has Minimal Effect on Plasma Viremia by Binley, James M., Clas, Brian, Gettie, Agegnehu, Vesanen, Mika, Montefiori, David C., Sawyer, Lynette, Booth, Jenny, Lewis, Mark, Marx, Preston A., Bonhoeffer, Sebastian, Moore, John P.

“…Antibody responses are often considered to play only a limited role in controlling viremia during chronic infections with human or simian immunodeficiency…”
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Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure by Ditzel, H J, Binley, J M, Moore, J P, Sodroski, J, Sullivan, N, Sawyer, L S, Hendry, R M, Yang, W P, Barbas, 3rd, C F, Burton, D R

“…As part of the goal of assembling a mixture of neutralizing human mAbs for possible prophylaxis and therapy of HIV-1 disease, we describe a strategy by which…”
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Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex by Wang, Chang Yi, Sawyer, Lynette S W, Murthy, Krishna K, Fang, Xinde

“…mAB B4 is a monoclonal antibody directed against HIV receptor complex. The antibody had broad neutralizating activity against HIV and provided postexposure…”
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Neutralizing antibody responses to autologous and heterologous isolates of human immunodeficiency virus by Wrin, T, Crawford, L, Sawyer, L, Weber, P, Sheppard, H W, Hanson, C V

“…Although laboratory-adapted strains of human immunodeficiency virus (HIV) are generally highly sensitive to neutralization by HIV-positive patient sera, we…”
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Mechanisms of the host cell effect on human immunodeficiency virus type 1 neutralization sensitivity by Sawyer, Lynette Susan Walker

“…Neutralizing antibody responses in vitro are a primary marker of host immunity and resistance to viral infection in vivo. However, studies of in vitro…”
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