Search Results - "Sawicki, W."

Physicochemical properties of direct compression tablets with spray dried and ball milled solid dispersions of tadalafil in PVP-VA by Wlodarski, K., Tajber, L., Sawicki, W.

“…[Display omitted] The aim of this research was to develop immediate release tablets comprising solid dispersion (IRSDTs) of tadalafil (Td) in a…”
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Physical stability of solid dispersions with respect to thermodynamic solubility of tadalafil in PVP-VA by Wlodarski, K., Sawicki, W., Kozyra, A., Tajber, L.

“…[Display omitted] The aim of this paper was to evaluate physical stability of solid dispersions in respect to the drug, tadalafil (Td), in vinylpyrrolidone and…”
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Physicochemical properties of tadalafil solid dispersions – Impact of polymer on the apparent solubility and dissolution rate of tadalafil by Wlodarski, K., Sawicki, W., Haber, K., Knapik, J., Wojnarowska, Z., Paluch, M., Lepek, P., Hawelek, L., Tajber, L.

“…[Display omitted] To improve solubility of tadalafil (Td), a poorly soluble drug substance (3μg/ml) belonging to the II class of the Biopharmaceutical…”
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A New Method To Identify Physically Stable Concentration of Amorphous Solid Dispersions (I): Case of Flutamide + Kollidon VA64 by Chmiel, K, Knapik-Kowalczuk, J, Jurkiewicz, K, Sawicki, W, Jachowicz, R, Paluch, M

“…In this paper, a novel approach to determine stable concentration in API-polymer systems is presented. As a model, binary amorphous mixtures flutamide (FL)…”
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Physical Stability of the Amorphous Anticholesterol Agent (Ezetimibe): The Role of Molecular Mobility by Knapik, J, Wojnarowska, Z, Grzybowska, K, Hawelek, L, Sawicki, W, Wlodarski, K, Markowski, J, Paluch, M

“…The purpose of this paper is to examine the role of molecular mobility in the recrystallization process from the amorphous state of the anticholesterol drug…”
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Dielectric Relaxation and Crystallization Kinetics of Ibuprofen at Ambient and Elevated Pressure by Adrjanowicz, K, Kaminski, K, Wojnarowska, Z, Dulski, M, Hawelek, L, Pawlus, S, Paluch, M, Sawicki, W

“…Dielectric spectroscopy (DS) was used to investigate the relaxation dynamics of supercooled and glassy ibuprofen at various isobaric and isothermal conditions…”
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EP24.07: Successful prenatal treatment of fetal supraventricular tachycardia with amiodarone: case report by Abdalla, N., Piorkowski, R., Stanirowski, P., Bachanek, M., Cendrowski, K., Sawicki, W.

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Molecular Dynamics, Physical Stability and Solubility Advantage from Amorphous Indapamide Drug by Wojnarowska, Z, Grzybowska, K, Hawelek, L, Dulski, M, Wrzalik, R, Gruszka, I, Paluch, M, Pienkowska, K, Sawicki, W, Bujak, P, Paluch, K. J, Tajber, L, Markowski, J

“…This study for the first time investigates physicochemical properties of amorphous indapamide drug (IND), which is a known diuretic agent commonly used in the…”
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The influence of amorphization methods on the apparent solubility and dissolution rate of tadalafil by Wlodarski, K., Sawicki, W., Paluch, K.J., Tajber, L., Grembecka, M., Hawelek, L., Wojnarowska, Z., Grzybowska, K., Talik, E., Paluch, M.

“…[Display omitted] This study for the first time investigates the solubility and dissolution rate of amorphous tadalafil (Td) – a poorly water soluble chemical…”
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Study of the Amorphous Glibenclamide Drug: Analysis of the Molecular Dynamics of Quenched and Cryomilled Material by Wojnarowska, Z, Grzybowska, K, Adrjanowicz, K, Kaminski, K, Paluch, M, Hawelek, L, Wrzalik, R, Dulski, M, Sawicki, W, Mazgalski, J, Tukalska, A, Bieg, T

“…Glibenclamide (GCM) is an oral hypoglycemic agent of the sulfonylurea group used in the treatment of non-insulin-dependent diabetes. Crystalline GCM is…”
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Molecular Dynamics Studies on the Water Mixtures of Pharmaceutically Important Ionic Liquid Lidocaine HCl by Wojnarowska, Z, Grzybowska, K, Hawelek, L, Swiety-Pospiech, A, Masiewicz, E, Paluch, M, Sawicki, W, Chmielewska, A, Bujak, P, Markowski, J

“…In this paper the molecular dynamics of a common local-anesthetic drug, lidocaine hydrochloride (LD-HCl), and its water mixtures were investigated. By means of…”
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Effect of amorphization method on telmisartan solubility and the tableting process by Lepek, P., Sawicki, W., Wlodarski, K., Wojnarowska, Z., Paluch, M., Guzik, L.

“…Comparison of crystalline and amorphous forms of telmisartan. Telmisartan (TLM), a poorly water-soluble angiotensin II receptor antagonist in crystalline form,…”
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Iron-catalyzed kinetic resolution of N-sulfonyl oxaziridines by Williamson, Kevin S., Sawicki, James W., Yoon, Tehshik P.

“…We have developed a highly selective kinetic resolution of N-sulfonyl oxaziridines. This reaction utilizes an inexpensive and easily synthesized iron…”
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Toward a Better Understanding of the Physical Stability of Amorphous Anti-Inflammatory Agents: The Roles of Molecular Mobility and Molecular Interaction Patterns by Rams-Baron, M, Wojnarowska, Z, Grzybowska, K, Dulski, M, Knapik, J, Jurkiewicz, K, Smolka, W, Sawicki, W, Ratuszna, A, Paluch, M

“…The aim of this article is to examine the crystallization tendencies of three chemically related amorphous anti-inflammatory agents, etoricoxib, celecoxib, and…”
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EP29.05: Value of selected ultrasound parameters of IETA group to differentiate endometrial polyps from another pathologies by Abdalla, N., Pazura, M., Bachanek, M., Cendrowski, K., Sawicki, W.

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An improved procedure for the preparation of Ru(bpz)3(PF6)2 via a high-yielding synthesis of 2,2'-bipyrazine by Schultz, Danielle M, Sawicki, James W, Yoon, Tehshik P

“…There has been a recent surge of interest in the use of transition metal polypyridyl complexes as visible light-absorbing photocatalysts for synthetic…”
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Adverse events associated with budesonide nasal irrigation reported to the US Food and Drug Administration: 2007 to 2022 by Rathi, Vinay K., Sawicki, Nicholas W., Schlosser, Rodney J., Soler, Zachary M., Scangas, George A., Workman, Alan D., Gray, Stacey T.

“…KEYPOINTS Between 2007 and 2022, the FDA received 119 US‐based reports mentioning budesonide nasal irrigation. Most reports were submitted by patients and…”
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“Click” Chemistry-Mediated Phenylene-Cored Carborane Dendrimers by Dash, Barada Prasanna, Satapathy, Rashmirekha, Bode, Barrie P, Reidl, Cory T, Sawicki, James W, Mason, Allen J, Maguire, John A, Hosmane, Narayan S

“…Phenylene-cored small dendrimers containing three to nine peripheral o-carborane clusters were synthesized via Cu(I)-catalyzed Huisgen-type azide alkyne…”
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OP07.06: Analysis of the diagnostic value of ADNEX model, CA125, HE4 and risk of malignancy algorithm in the presurgical assessment of adnexal masses by Abdalla, N., Trojanowski, S., Cendrowski, K., Wnuk, A., Sawicki, W.

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OC04.06: Analysis of the diagnostic value of gynecologic imaging reporting and data system, HE4 and CA125 in the presurgical assessment of adnexal tumors by Abdalla, N., Kania, M., Bachanek, M., Cendrowski, K., Sawicki, W.

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