Search Results - "Sawicki, T."
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Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study
Published in Diabetologia (01-09-2009)“…Aims/hypothesis The aim of this cohort study was to investigate the risk of malignant neoplasms and mortality in patients with diabetes treated either with…”
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mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2018)“…Cells respond to iron deficiency by activating iron-regulatory proteins to increase cellular iron uptake and availability. However, it is not clear how cells…”
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3
Circulating Branched Chain Amino Acids and Cardiometabolic Disease
Published in Journal of the American Heart Association (02-04-2024)“…Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy balance, and signaling pathways. Changes in BCAA homeostasis have emerged as…”
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4
Reduction in mitochondrial iron alleviates cardiac damage during injury
Published in EMBO molecular medicine (01-03-2016)“…Excess cellular iron increases reactive oxygen species (ROS) production and causes cellular damage. Mitochondria are the major site of iron metabolism and ROS…”
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Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8
Published in eLife (09-04-2021)“…Chronic loss of Augmenter of Liver Regeneration (ALR) results in mitochondrial myopathy with cataracts; however, the mechanism for this disorder remains…”
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Preliminary Virtual Constraint-Based Control Evaluation on a Pediatric Lower-Limb Exoskeleton
Published in Bioengineering (Basel) (01-06-2024)“…Pediatric gait rehabilitation and guidance strategies using robotic exoskeletons require a controller that encourages user volitional control and participation…”
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Optimized protocol for quantification of mitochondrial non-heme and heme iron content in mouse tissues and cultured cells
Published in STAR protocols (17-03-2023)“…Impaired mitochondrial iron metabolism is associated with aging and a variety of diseases, and there is a growing need to accurately quantify mitochondrial…”
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Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life
Published in JCI insight (24-04-2023)“…BACKGROUNDElevated circulating branched chain amino acids (BCAAs), measured at a single time point in middle life, are strongly associated with an increased…”
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Hybrid Zero Dynamics Control for Gait Guidance of a Novel Adjustable Pediatric Lower-Limb Exoskeleton
Published in Bioengineering (Basel) (12-05-2022)“…Exoskeleton technology has undergone significant developments for the adult population but is still lacking for the pediatric population. This paper presents…”
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Human Factors Assessment of a Novel Pediatric Lower-Limb Exoskeleton
Published in Robotics (Basel) (01-02-2023)“…While several lower-limb exoskeletons have been designed for adult patients, there remains a lack of pediatric-oriented devices. This paper presented a human…”
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11
Screening for diabetes: hope and despair
Published in Diabetologia (01-06-2012)“…This commentary discusses whether screening for type 2 diabetes or earlier normalisation of blood glucose levels or initiation of non-antihyperglycaemic agents…”
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Commentary: Does additional benefit justify additional costs of insulin analogues?
Published in BMJ (14-09-2011)“…[...]the institute searched for randomised controlled trials of at least six months' duration and with outcomes related to diabetes complications, quality of…”
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13
Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21
Published in JCI insight (12-07-2018)“…The role of posttranscriptional metabolic gene regulatory programs in diabetes is not well understood. Here, we show that the RNA-binding protein…”
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14
Systematic review of studies of self-management of oral anticoagulation
Published in Thrombosis and haemostasis (01-02-2004)“…This work is aimed at assessing the evidence for the possible improvement of therapeutic control of anticoagulation, reduction of major bleedings,…”
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15
Acarbose for prevention of diabetes, hypertension and cardiovascular events? A critical analysis of the STOP-NIDDM data
Published in Diabetologia (01-03-2004)“…Cardiovascular morbidity and mortality is a major and still unresolved threat to patients with reduced glucose tolerance and Type 2 diabetes mellitus. In…”
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Computationally efficient implementation of robust controllers in active magnetic bearing systems
Published in Mechanical systems and signal processing (01-10-2020)“…•A novel method is proposed to lower computational cost of controllers via dual-rate implementation•The method can be used with any generalized MIMO…”
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A Structured Teaching and Self-management Program for Patients Receiving Oral Anticoagulation: A Randomized Controlled Trial
Published in JAMA : the journal of the American Medical Association (13-01-1999)“…CONTEXT Control of oral anticoagulation therapy has been reported to often be inadequate. Previous retrospective investigations suggest that patients'…”
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18
Design and Evaluation of a Pediatric Lower-Limb Exoskeleton Joint Actuator
Published in Actuators (01-12-2020)“…Lower-limb exoskeletons have undergone significant developments for aiding in the ambulation of adults with gait impairment. However, advancements in…”
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Robust control of active magnetic bearing systems with an add-on controller to cancel gyroscopic effects: Is it worth it?
Published in Journal of vibration and control (01-12-2021)“…One of the performance-limiting factors in the design of robust controllers for active magnetic bearing systems is the fact that the controller needs to be…”
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20
Smoking is associated with progression of diabetic nephropathy
Published in Diabetes care (01-02-1994)“…Smoking is associated with progression of diabetic nephropathy. P T Sawicki , U Didjurgeit , I Mühlhauser , R Bender , L Heinemann and M Berger Department of…”
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