Search Results - "Sawaya, Raymond"

The influence of maximum safe resection of glioblastoma on survival in 1229 patients: Can we do better than gross-total resection? by Li, Yan Michael, Suki, Dima, Hess, Kenneth, Sawaya, Raymond

“…Glioblastoma multiforme (GBM) is the most common and deadliest primary brain tumor. The value of extent of resection (EOR) in improving survival in patients…”
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Extent of Resection of Glioblastoma Revisited: Personalized Survival Modeling Facilitates More Accurate Survival Prediction and Supports a Maximum-Safe-Resection Approach to Surgery by MARKO, Nicholas F, WEIL, Robert J, SCHROEDER, Jason L, LANG, Frederick F, SUKI, Dima, SAWAYA, Raymond E

“…Approximately 12,000 glioblastomas are diagnosed annually in the United States. The median survival rate for this disease is 12 months, but individual survival…”
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Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma by Lang, Frederick F, Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W K Alfred, Sawaya, Raymond, Weinberg, Jeffrey S, Prabhu, Sujit S, Rao, Ganesh, Fuller, Gregory N, Aldape, Kenneth D, Gumin, Joy, Vence, Luis M, Wistuba, Ignacio, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Dirven, Clemens M F, Tejada, Sonia, Valle, Ricardo D, Alonso, Marta M, Ewald, Brett, Peterkin, Joanna J, Tufaro, Frank, Fueyo, Juan

“…Purpose DNX-2401 (Delta-24-RGD; tasadenoturev) is a tumor-selective, replication-competent oncolytic adenovirus. Preclinical studies demonstrated antiglioma…”
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Mesenchymal stem cells as natural biofactories for exosomes carrying miR-124a in the treatment of gliomas by Lang, Frederick M, Hossain, Anwar, Gumin, Joy, Momin, Eric N, Shimizu, Yuzaburo, Ledbetter, Dan, Shahar, Tal, Yamashita, Shinji, Parker Kerrigan, Brittany, Fueyo, Juan, Sawaya, Raymond, Lang, Frederick F

“…MicroRNAs (miRs) are promising new therapeutics for glioblastoma. However, which miRs are most effective against glioblastomas and how these miRs should be…”
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The role of autophagy in cancer development and response to therapy by Kondo, Seiji, Kondo, Yasuko, Kanzawa, Takao, Sawaya, Raymond

“…Autophagy is a process in which subcellular membranes undergo dynamic morphological changes that lead to the degradation of cellular proteins and cytoplasmic…”
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Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways by Aoki, Hiroshi, Takada, Yasunari, Kondo, Seiji, Sawaya, Raymond, Aggarwal, Bharat B, Kondo, Yasuko

“…Autophagy is a response of cancer cells to various anticancer therapies. It is designated as programmed cell death type II and characterized by the formation…”
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Incidence Proportions of Brain Metastases in Patients Diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System by BARNHOLTZ-STOAN, Jill S, SLOAN, Andrew E, DAVIS, Faith G, VIGNEAU, Fawn D, PING LAI, SAWAYA, Raymond E

“…Population-based estimates of the incidence of brain metastases are not generally available. The purpose of this study was to calculate population-based…”
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Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma by SAMPSON, John H, HEIMBERGER, Amy B, REARDON, David A, SAWAYA, Raymond, SCHMITTLING, Robert J, WEIMING SHI, VREDENBURGH, James J, BIGNER, Darell D, ARCHER, Gary E, ALDAPE, Kenneth D, FRIEDMAN, Allan H, FRIEDMAN, Henry S, GILBERT, Mark R, HERNDON, James E, MCLENDON, Roger E, MITCHELL, Duane A

“…Immunologic targeting of tumor-specific gene mutations may allow precise eradication of neoplastic cells without toxicity. Epidermal growth factor receptor…”
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FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells by Zhang, Yujian, Zhang, Nu, Dai, Bingbing, Liu, Mingguang, Sawaya, Raymond, Xie, Keping, Huang, Suyun

“…We previously found that FoxM1B is overexpressed in human glioblastomas and that forced FoxM1B expression in anaplastic astrocytoma cells leads to the…”
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A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models by Zinn, Pascal O, Singh, Sanjay K, Kotrotsou, Aikaterini, Hassan, Islam, Thomas, Ginu, Luedi, Markus M, Elakkad, Ahmed, Elshafeey, Nabil, Idris, Tagwa, Mosley, Jennifer, Gumin, Joy, Fuller, Gregory N, de Groot, John F, Baladandayuthapani, Veera, Sulman, Erik P, Kumar, Ashok J, Sawaya, Raymond, Lang, Frederick F, Piwnica-Worms, David, Colen, Rivka R

“…Radiomics is the extraction of multidimensional imaging features, which when correlated with genomics, is termed radiogenomics. However, radiogenomic…”
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Glioblastoma Cancer-Initiating Cells Inhibit T-Cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway by Wei, Jun, Barr, Jason, Kong, Ling-Yuan, Wang, Yongtao, Wu, Adam, Sharma, Amit K, Gumin, Joy, Henry, Verlene, Colman, Howard, Priebe, Waldemar, Sawaya, Raymond, Lang, Frederick F, Heimberger, Amy B

“…Glioblastoma multiforme (GBM) is a lethal cancer that responds poorly to radiotherapy and chemotherapy. Glioma cancer-initiating cells have been shown to…”
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Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression by Wei, Jun, Barr, Jason, Kong, Ling-Yuan, Wang, Yongtao, Wu, Adam, Sharma, Amit K, Gumin, Joy, Henry, Verlene, Colman, Howard, Sawaya, Raymond, Lang, Frederick F, Heimberger, Amy B

“…Purpose: Glioblastoma multiforme is a lethal cancer that responds poorly to therapy. Glioblastoma multiforme cancer-initiating cells have been shown to mediate…”
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Glioma-Associated Cytomegalovirus Mediates Subversion of the Monocyte Lineage to a Tumor Propagating Phenotype by DZIURZYNSKI, Kristine, JUN WEI, RAO, Ganesh, SAWAYA, Raymond, HEIMBERGER, Amy B, WEI QIAO, AZIZ HATIBOGLU, Mustafa, KONG, Ling-Yuan, WU, Adam, YONGTAO WANG, CAHILL, Daniel, LEVINE, Nicholas, PRABHU, Sujit

“…Cytomegalovirus (CMV) has been ubiquitously detected within high-grade gliomas, but its role in gliomagenesis has not been fully elicited. Glioblastoma…”
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The history of neurosurgery at Baylor College of Medicine by Srinivasan, Visish M, Hadley, Caroline C, Patel, Akash J, Ehni, Bruce L, Weiner, Howard L, Rao, Ganesh, Lang, Frederick F, Sawaya, Raymond E, Yoshor, Daniel

“…The development of neurosurgery at Baylor College of Medicine began with the medical school's relocation to the new Texas Medical Center in Houston in 1943. An…”
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Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients by HEIMBERGER, Amy B, HLATKY, Roman, SUKI, Dima, YANG, David, WEINBERG, Jeff, GILBERT, Mark, SAWAYA, Raymond, ALDAPE, Kenneth

“…Purpose: The epidermal growth factor receptor (EGFR) is overexpressed in ∼50% to 60% of glioblastoma multiforme tumors, and the most common EGFR mutant,…”
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Comparative risk of leptomeningeal disease after resection or stereotactic radiosurgery for solid tumor metastasis to the posterior fossa by SUKI, Dima, ABOUASSI, Hiba, PATEL, Akash J, SAWAYA, Raymond, WEINBERG, Jeffrey S, GROVES, Morris D

“…The authors tested the hypothesis that patients with metastatic posterior fossa lesions (MPFLs) treated with resection have a higher risk of leptomeningeal…”
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Correction: Detecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients by Humphries, William, Wang, Yongtao, Qiao, Wei, Reina-Ortiz, Chantal, Abou-Ghazal, Mohamed K, Crutcher, Lamonne M, Wei, Jun, Kong, Ling-Yuan, Sawaya, Raymond, Rao, Ganesh, Weinberg, Jeffrey, Prabhu, Sujit S, Fuller, Gregory N, Heimberger, Amy B

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy by DAIDO, Shigeru, YAMAMOTO, Akitsugu, FUJIWARA, Keishi, SAWAYA, Raymond, KONDO, Seiji, RONDO, Yasuko

“…DNA-dependent protein kinase (DNA-PK) plays a major role in the repair of DNA double-strand breaks induced by ionizing radiation (IR). Lack of DNA-PK causes…”
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Forkhead Box M1 Is Regulated by Heat Shock Factor 1 and Promotes Glioma Cells Survival under Heat Shock Stress by Dai, Bingbing, Gong, Aihua, Jing, Zhitao, Aldape, Kenneth D., Kang, Shin-Hyuk, Sawaya, Raymond, Huang, Suyun

“…The forkhead box M1 (FoxM1) is a key transcription factor regulating multiple aspects of cell biology. Prior studies have shown that FoxM1 is overexpressed in…”
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The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas by Mohamed Abou-Ghazal, David S. Yang, Wei Qiao, Chantal Reina-Ortiz, Jun Wei, Ling-Yuan Kong, Gregory N. Fuller, Nobuyoshi Hiraoka, Waldemar Priebe, Raymond Sawaya, Amy B. Heimberger

“…Purpose: The signal transducer and activator of transcription 3 (STAT3) is frequently overexpressed in most cancers, propagates tumorigenesis, and is a key…”
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