Search Results - "Sawant, Krutika K"

Rivastigmine-loaded PLGA and PBCA nanoparticles: Preparation, optimization, characterization, in vitro and pharmacodynamic studies by Joshi, Shrinidh A., Chavhan, Sandip S., Sawant, Krutika K.

“…Effect of RT NPs after intraveneous administration on the escape latency achieved in Morris Water Maze test in saline and scopolamine treated mice. Sustained…”
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An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery by Petkar, Kailash C, Patil, Suyash M, Chavhan, Sandip S, Kaneko, Kan, Sawant, Krutika K, Kunda, Nitesh K, Saleem, Imran Y

“…The development of vaccines is one of the most significant medical accomplishments which has helped to eradicate a large number of diseases. It has undergone…”
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Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor by Manjappa, Arehalli S., Chaudhari, Kiran R., Venkataraju, Makam P., Dantuluri, Prudhviraju, Nanda, Biswarup, Sidda, Chennakesavulu, Sawant, Krutika K., Ramachandra Murthy, Rayasa S.

“…A great deal of effort has been made over the years to develop liposomes that have targeting vectors (oligosaccharides, peptides, proteins and vitamins)…”
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Albumin based versatile multifunctional nanocarriers for cancer therapy: Fabrication, surface modification, multimodal therapeutics and imaging approaches by Kudarha, Ritu R., Sawant, Krutika K.

“…Albumin is a versatile protein used as a carrier system for cancer therapeutics. As a carrier it can provide tumor specificity, reduce drug related toxicity,…”
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Nanostructured materials in drug and gene delivery: a review of the state of the art by Petkar, Kailash C, Chavhan, Sandip S, Agatonovik-Kustrin, Snezana, Sawant, Krutika K

“…A wide variety of drug delivery systems have been developed, each with its own advantages and limitations, but the important goals of all of the systems are to…”
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Oral Bioavailability Enhancement of Amisulpride: Complexation and its Pharmacokinetics and Pharmacodynamics Evaluations by B, Prajapati Jagruti, K, Sawant Krutika, Dubey, Bhramanand

“…Many CNS drugs have low bioavailability due to their poor water solubility of extensive first-pass metabolism and hence have less effectiveness. The present…”
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Self-nanoemulsifying drug delivery system for adefovir dipivoxil: Design, characterization, in vitro and ex vivo evaluation by Gupta, Shweta, Chavhan, Sandip, Sawant, Krutika K.

“…[Display omitted] ► Solid-SNEDDS (S-SNEDDS) prepared by lyophilization using D-mannitol. ► Drug release from SNEDDS was higher than plain drug suspension and…”
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Design and characterization of dual responsive mesoporous silica nanoparticles for breast cancer targeted therapy by Bhavsar, Dhaval B., Patel, Vijay, Sawant, Krutika K.

“…•Redox-pH dual responsive mesoporous silica nanoparticles (MSNs) were synthesized for active breast cancer targeting.•The MSNs showed triggered drug release…”
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Self microemulsifying drug delivery system of lurasidone hydrochloride for enhanced oral bioavailability by lymphatic targeting: In vitro, Caco-2 cell line and in vivo evaluation by Patel, Mitali H., Sawant, Krutika K.

“…The global aim of this research was to develop and evaluate self-microemulsifying drug delivery system (SMEDDS) to improve oral bioavailability of Lurasidone…”
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Development, evaluation and clinical studies of Acitretin loaded nanostructured lipid carriers for topical treatment of psoriasis by Agrawal, Yogeeta, Petkar, Kailash C., Sawant, Krutika K.

“…The objective of the present study was to formulate and characterize Acitretin loaded Nanostructured Lipid Carriers (ActNLCs), to understand in vitro drug…”
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Glucagon: Delivery advancements for hypoglycemia management by Kumar, Samarth, Sanap, Sachin N., Pandey, Prachi, Khopade, Ajay, Sawant, Krutika K.

“…[Display omitted] •Celebrating 100th anniversary of glucagon's discovery.•Blood glucose level <54 mg/dL in patients referred as severe hypoglycemia.•GlucaGen®…”
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Nimodipine loaded PLGA nanoparticles: formulation optimization using factorial design, characterization and in vitro evaluation by Mehta, Ashish K, Yadav, Khushwant S, Sawant, Krutika K

“…The present study was aimed at developing a sustained release formulation of Nimodipine (NIM) nanoparticles using the biodegradable polymers, poly…”
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Chondroitin sulfate conjugation facilitates tumor cell internalization of albumin nanoparticles for brain-targeted delivery of temozolomide via CD44 receptor-mediated targeting by Kudarha, Ritu R., Sawant, Krutika K.

“…In the present investigation, temozolomide (TMZ) loaded chondroitin sulfate conjugated albumin nanoparticles (CS-TNPs) were fabricated by desolvation method…”
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Fabrication of solid lipid nanoparticles of lurasidone HCl for oral delivery: optimization, in vitro characterization, cell line studies and in vivo efficacy in schizophrenia by Patel, Mitali H., Mundada, Veenu P., Sawant, Krutika K.

“…Objective: The aim of the present investigation was to investigate the efficacy of solid lipid nanoparticles (SLNs) to enhance the absorption and…”
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Novel Discoveries and Clinical Advancements for Treating Onychomycosis: A Mechanistic Insight by Kumar Behera, Jitesh, Kumar, Samarth, Sharma, Rajeev, Jain, Ashay, Kumar Garg, Neeraj, Khopade, Ajay, Sawant, Krutika K, Singh, Ranjit, Nirbhavane, Pradip

“…Onychomycosis continues to be the most challenging disease condition for pharmaceutical scientists to develop an effective drug delivery system. Treatment…”
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Novel Drug Delivery Approach via Self-Microemulsifying Drug Delivery System for Enhancing Oral Bioavailability of Asenapine Maleate: Optimization, Characterization, Cell Uptake, and In Vivo Pharmacokinetic Studies by Patel, Mitali H., Mundada, Veenu P., Sawant, Krutika K.

“…Asenapine maleate (AM)-loaded self-microemulsifying drug delivery system (AM-SMEDDS) was prepared to increase its oral bioavailability. AM-SMEDDS was developed…”
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Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery by Pandey, Abhijeet P., Sawant, Krutika K.

“…Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid delivery vehicles. Gene delivery using PEI involves condensation of DNA…”
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Modified Nanoprecipitation Method for Preparation of Cytarabine-Loaded PLGA Nanoparticles by Yadav, Khushwant S., Sawant, Krutika K.

“…The present investigation was aimed at developing cytarabine-loaded poly(lactide-coglycolide) (PLGA)-based biodegradable nanoparticles by a modified…”
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Comparative Study for Optimization of Pharmaceutical Self-Emulsifying Pre-concentrate by Design of Experiment and Artificial Neural Network by Parikh, Kinjal J., Sawant, Krutika K.

“…The present investigation aimed to optimize the critical parameters affecting the globule size of self-emulsifying drug delivery system. Based on preliminary…”
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Development of Novel Octanoyl Chitosan Nanoparticles for Improved Rifampicin Pulmonary Delivery: Optimization by Factorial Design by Petkar, Kailash C., Chavhan, Sandip, Kunda, N., Saleem, I., Somavarapu, S., Taylor, Kevin M. G., Sawant, Krutika K.

“…A novel hydrophobic chitosan derivative, octanoyl chitosan (OC) with improved organic solubility was synthesized, characterized, and employed for the…”
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