Search Results - "Sawane, Kento"

Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity by Yoshii, Ken, Hosomi, Koji, Sawane, Kento, Kunisawa, Jun

“…Vitamins are micronutrients that have physiological effects on various biological responses, including host immunity. Therefore, vitamin deficiency leads to…”
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Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota by Hosomi, Koji, Saito, Mayu, Park, Jonguk, Murakami, Haruka, Shibata, Naoko, Ando, Masahiro, Nagatake, Takahiro, Konishi, Kana, Ohno, Harumi, Tanisawa, Kumpei, Mohsen, Attayeb, Chen, Yi-An, Kawashima, Hitoshi, Natsume-Kitatani, Yayoi, Oka, Yoshimasa, Shimizu, Hidenori, Furuta, Mari, Tojima, Yoko, Sawane, Kento, Saika, Azusa, Kondo, Saki, Yonejima, Yasunori, Takeyama, Haruko, Matsutani, Akira, Mizuguchi, Kenji, Miyachi, Motohiko, Kunisawa, Jun

“…The gut microbiome is an important determinant in various diseases. Here we perform a cross-sectional study of Japanese adults and identify the Blautia genus,…”
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Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults by Ogawa, Toshimi, Sawane, Kento, Ookoshi, Kouta, Kawashima, Ryuta

“…The effects of docosahexaenoic acid supplements on cognitive function have long been demonstrated, but the effects of alpha-linolenic acid, a precursor of…”
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12-Hydroxyeicosapentaenoic acid inhibits foam cell formation and ameliorates high-fat diet-induced pathology of atherosclerosis in mice by Nagatake, Takahiro, Shibata, Yuki, Morimoto, Sakiko, Node, Eri, Sawane, Kento, Hirata, So-ichiro, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Saika, Azusa, Hosomi, Koji, Tomonaga, Takeshi, Kunisawa, Jun

“…Atherosclerosis is a chronic inflammatory disease associated with macrophage aggregate and transformation into foam cells. In this study, we sought to…”
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Availability of dietary secoisolariciresinol diglucoside on borderline blood cholesterol level in men: a randomized, parallel, controlled, double-blinded clinical trial by Ookoshi, Kouta, Sawane, Kento, Fukumitsu, Satoshi, Aida, Kazuhiko

“…Borderline low-density lipoprotein cholesterol levels (120–139 mg/dl) increase the risk of cardiovascular disease. Therefore, the use of functional dietary…”
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Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice by Sawane, Kento, Nagatake, Takahiro, Hosomi, Koji, Hirata, So-Ichiro, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Suzuki, Hidehiko, Matsunaga, Ayu, Fukumitsu, Satoshi, Aida, Kazuhiko, Tomonaga, Takeshi, Arita, Makoto, Kunisawa, Jun

“…The metabolism and generation of bioactive lipid mediators are key events in the exertion of the beneficial effects of dietary omega-3 fatty acids in the…”
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Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL‐expressing plasmacytoid dendritic cells in mice by Hirata, So‐ichiro, Nagatake, Takahiro, Sawane, Kento, Hosomi, Koji, Honda, Tetsuya, Ono, Sachiko, Shibuya, Noriko, Saito, Emiko, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Suzuki, Hidehiko, Matsunaga, Ayu, Tomonaga, Takeshi, Kiyono, Hiroshi, Kabashima, Kenji, Arita, Makoto, Kunisawa, Jun

“…Background Maternal dietary exposures are considered to influence the development of infant allergies through changes in the composition of breast milk. Cohort…”
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Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques by Nagatake, Takahiro, Kishino, Shigenobu, Urano, Emiko, Murakami, Haruka, Kitamura, Nahoko, Konishi, Kana, Ohno, Harumi, Tiwari, Prabha, Morimoto, Sakiko, Node, Eri, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Sawane, Kento, Honda, Tetsuya, Inoue, Asuka, Uwamizu, Akiharu, Matsuzaka, Takashi, Miyamoto, Yoichi, Hirata, So-ichiro, Saika, Azusa, Shibata, Yuki, Hosomi, Koji, Matsunaga, Ayu, Shimano, Hitoshi, Arita, Makoto, Aoki, Junken, Oka, Masahiro, Matsutani, Akira, Tomonaga, Takeshi, Kabashima, Kenji, Miyachi, Motohiko, Yasutomi, Yasuhiro, Ogawa, Jun, Kunisawa, Jun

“…Dietary ω3 fatty acids have important health benefits and exert their potent bioactivity through conversion to lipid mediators. Here, we demonstrate that…”
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Dietary coconut oil ameliorates skin contact hypersensitivity through mead acid production in mice by Tiwari, Prabha, Nagatake, Takahiro, Hirata, So‐ichiro, Sawane, Kento, Saika, Azusa, Shibata, Yuki, Morimoto, Sakiko, Honda, Tetsuya, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Tomonaga, Takeshi, Kiyono, Hiroshi, Kabashima, Kenji, Kunisawa, Jun

“…Coconut oil is used as a dietary oil worldwide, and its healthy effects are recognized by the fact that coconut oil is easy to digest, helps in weight…”
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Identification of Human Gut Microbiome Associated with Enterolignan Production by Sawane, Kento, Hosomi, Koji, Park, Jonguk, Ookoshi, Kouta, Nanri, Hinako, Nakagata, Takashi, Chen, Yi-An, Mohsen, Attayeb, Kawashima, Hitoshi, Mizuguchi, Kenji, Miyachi, Motohiko, Kunisawa, Jun

“…Dietary plant lignans are converted inside the gut to enterolignans enterodiol (ED) and enterolactone (EL), which have several biological functions, and health…”
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Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells by Hirata, So-ichiro, Sawane, Kento, Adachi, Jun, Isoyama, Junko, Sugiura, Yuki, Matsunaga, Ayu, Hosomi, Koji, Tomonaga, Takeshi, Suematsu, Makoto, Nagatake, Takahiro, Kunisawa, Jun

“…Homeostatic generation of T cells, which occurs in the thymus, is controlled at least in part by endogenous cytokines and ligands. In addition, nutritional…”
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Anti-allergic property of dietary phytoestrogen secoisolariciresinol diglucoside through microbial and β-glucuronidase-mediated metabolism by Sawane, Kento, Nagatake, Takahiro, Hosomi, Koji, Kunisawa, Jun

“…Phytoestrogens play pivotal roles in controlling not only the endocrine system but also inflammatory metabolic disorders. However, the effects of dietary…”
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Availability of dietary secoisolariciresinol diglucoside on borderline blood cholesterol level in men: A randomized, parallel, controlled, double-blinded clinical trial by Ookoshi, Kouta, Sawane, Kento, Fukumitsu, Satoshi, Aida, Kazuhiko

“…Borderline low-density lipoprotein cholesterol (LDL-C) levels (120-139 mg/dL) increase the risk of cardiovascular disease. Therefore, the use of functional…”
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ω3 fatty acid metabolite, 12‐hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α by Saika, Azusa, Nagatake, Takahiro, Hirata, So‐ichiro, Sawane, Kento, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Morimoto, Sakiko, Node, Eri, Tiwari, Prabha, Hosomi, Koji, Matsunaga, Ayu, Honda, Tetsuya, Tomonaga, Takeshi, Arita, Makoto, Kabashima, Kenji, Kunisawa, Jun

“…ω3 fatty acids show potent bioactivities via conversion into lipid mediators; therefore, metabolism of dietary lipids is a critical determinant in the…”
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LC‐MS/MS determination of phosphatidylcholine hydroperoxide and its truncated products in human blood plasma (1001.9) by Miyazawa, Teruo, Kato, Shunji, Sawane, Kento, Miyazawa, Taiki, Nakagawa, Kiyotaka

“…Accumulation of phosphatidylcholine hydroperoxide (PCOOH), a primary oxidation product of phosphatidylcholine (PC), in the blood plasma has been observed in…”
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