Search Results - "Sawada, Kaichiro"
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Skeletal and mineral metabolic effects of risedronate in a rat model of high-turnover renal osteodystrophy
Published in Journal of bone and mineral metabolism (01-07-2020)“…Introduction High-turnover bone disease is a major consequence of SHPT and may explain the high risk for fracture in patients with advanced chronic kidney…”
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2
Parathyroid hormone-producing cells exist in adipose tissues surrounding the parathyroid glands in hemodialysis patients with secondary hyperparathyroidism
Published in Scientific reports (24-02-2020)“…Possible ectopic parathyroid hormone (PTH) production in adipose tissues surrounding hyperplastic parathyroid glands was examined in patients with secondary…”
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Study of the Effects of Deuterium-Depleted Water on the Expression of GLUT4 and Insulin Resistance in the Muscle Cell Line C2C12
Published in Biomedicines (06-08-2024)“…Deuterium-depleted water (DDW) is used in the treatment of many diseases, including cancer and diabetes. To detect the effect of DDW on gene expression and…”
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Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity
Published in Communications chemistry (21-11-2023)“…Seleno-insulin, a class of artificial insulin analogs, in which one of the three disulfide-bonds (S-S’s) of wild-type insulin (Ins) is replaced by a…”
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Regulation of Renin Expression by Β1-Integrin in As4.1 Juxtaglomerular Line Cells
Published in Biomedicines (09-02-2023)“…(1) Background: Renal dysfunction and hypertension are mutually aggravating factors; however, the details of their interaction remain unclear. In a study using…”
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Feasibility of photodynamic therapy for secondary hyperparathyroidism in chronic renal failure rats
Published in Clinical and experimental nephrology (01-08-2017)“…Background Feasibility of photodynamic therapy (PDT) for secondary hyperparathyroidism (SHPT) was examined in a rat model of SHPT. Methods A photosensitizer,…”
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New Developments in CKD-MBD. Cell Biology of parathyroid in CKD
Published in Clinical calcium (01-12-2014)“…Parathyroid monitors the calcium concentration in blood by signals from calcium-sensing receptors, adjusts secretion of parathyroid hormone to keep constant…”
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Maternal mRNAs of PEM and macho 1, the ascidian muscle determinant, associate and move with a rough endoplasmic reticulum network in the egg cortex
Published in Development (Cambridge) (01-12-2003)“…Localization of maternal mRNAs in the egg cortex is an essential feature of polarity in embryos of Drosophila , Xenopus and ascidians. In ascidians, maternal…”
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Upregulation of α3β1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy
Published in Journal of diabetes research (01-01-2016)“…Background. Podocyte injury plays an important role in the onset and progression of diabetic nephropathy (DN). Downregulation of α3β1-integrin expression in…”
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Evaluation of bioartificial renal tubule device prepared with human renal proximal tubular epithelial cells cultured in serum-free medium
Published in Journal of artificial organs (01-09-2013)“…Bioartificial renal tubule devices (BTD) use cell therapy to improve conditions commonly observed in recipients of artificial kidneys for treatment of kidney…”
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Maternal macho-1 is an intrinsic factor that makes cell response to the same FGF signal differ between mesenchyme and notochord induction in ascidian embryos
Published in Development (Cambridge) (01-11-2003)“…An extracellular signaling molecule acts on several types of cells, evoking characteristic and different responses depending on intrinsic factors in the…”
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Macho-1 functions as transcriptional activator for muscle formation in embryos of the ascidian Halocynthia roretzi
Published in Gene Expression Patterns (01-02-2005)“…Various kinds of maternal factor that play crucial roles in embryogenesis are present and localized in the ascidian egg cytoplasm. Localized maternal mRNA of…”
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Enhancement of permeability in endothelial cells for the development of an antithrombogenic bioartificial hemofilter
Published in Biotechnology and bioengineering (15-10-2008)“…For the development of an antithrombogenic bioartificial hemofilter, in which the inner surface of hollow fibers is lined by endothelial cells, it is essential…”
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Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury
Published in Nephron extra (30-04-2014)“…Background/Aims:TSPAN8 encoding tetraspanin-8 was identified as a candidate gene for immunoglobulin A nephropathy (IgAN) by a genome-wide association study…”
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Prevention of LLC-PK1 cell overgrowth in a bioartificial renal tubule device using a MEK inhibitor, U0126
Published in Journal of biotechnology (15-10-2007)Get full text
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AKI Promotes Osteoid Formation Through Increased PTH Secretion in Rats: SA-PO212
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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498-P: Involvement of Phosphorylation of Beta-1 Integrin in Renin Production and Blood Pressure Regulation in Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Diabetic nephropathy (DN) and hypertension exacerbate each other, but many aspects of the mechanisms between these two pathologies remain unclear. The…”
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Impact of Parathyroidectomy on Serum FGF23 and Soluble Klotho in Hemodialysis Patients With Severe Secondary Hyperparathyroidism
Published in The journal of clinical endocrinology and metabolism (01-04-2014)“…Context: Klotho is a transmembrane protein that functions as a coreceptor for fibroblast growth factor 23 (FGF23). Klotho is cleaved and released into the…”
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Renin Production and Involvement of ß1 Integrin in Blood Pressure Regulation in Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Diabetic nephropathy (DN) and hypertension mutually exacerbate each other, but many aspects of the mechanisms of these two pathologies remain unclear. The…”
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SaO028FGF23 MITIGATES HYPERPHOSPHATEMIA AND CAUSES LOW 1,25-DIHYDROXYVITAMIN D LEVELS AFTER ACUTE KIDNEY INJURY IN RATS
Published in Nephrology, dialysis, transplantation (01-05-2018)Get full text
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