Search Results - "Sawabu, Norio"

Appropriate steroid therapy for autoimmune pancreatitis based on long-term outcome by Kamisawa, Terumi, Okamoto, Atsutake, Wakabayashi, Tokio, Watanabe, Hiroyuki, Sawabu, Norio

“…Objective. Because autoimmune pancreatitis (AIP) responds well to corticosteroids, many AIP patients are given this treatment. However, there is no consensus…”
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Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer by Jiang, Pei-Hong, Motoo, Yoshiharu, Garcia, Stéphane, Iovanna, Juan Lucio, Pébusque, Marie-Josèphe, Sawabu, Norio

“…AIM： Overexpression of tumor protein p53-induced nudear protein 1 （TP53INP1） induces G1 cell cycle arrest and increases p53-mediated apoptosis. To clarify the…”
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Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells by Jiang, Pei-Hong, Motoo, Yoshiharu, Sawabu, Norio, Minamoto, Toshinari

“…AIM： TO investigate the expression of genes involved in the gemcitabine-induced cytotoxicity in human pancreatic cancer cells. METHODS： A human pancreatic…”
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Long-term prognosis of duct-narrowing chronic pancreatitis: strategy for steroid treatment by Wakabayashi, Tokio, Kawaura, Yukimitsu, Satomura, Yositake, Watanabe, Hiroyuki, Motoo, Yoshiharu, Sawabu, Norio

“…The purpose of this study was to assess the long-term prognosis in patients with duct-narrowing chronic pancreatitis (DNCP) and determine the indications for…”
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Serum tumor markers and molecular biological diagnosis in pancreatic cancer by Sawabu, Norio, Watanabe, Hiroyuki, Yamaguchi, Yasushi, Ohtsubo, Koushirou, Motoo, Yoshiharu

“…Recent studies on genetic abnormalities in pancreatic ductal cancer have led to the investigation of tumor markers and genetic markers in both serum and…”
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Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture by Okada, Gensaku, Watanabe, Hiroyuki, Ohtsubo, Koushiro, Mouri, Hisatsugu, Yamaguchi, Yasushi, Motoo, Yoshiharu, Sawabu, Norio

“…Since telomerase expression is highly prevalent in human cancers, the quantitation of serum/plasma hTERT (human telomerase reverse transcriptase) mRNA levels…”
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Consensus of primary care in acute pancreatitis in Japan by Otsuki, Makoto, Hirota, Masahiko, Arata, Shinju, Koizumi, Masaru, Kawa, Shigeyuki, Kamisawa, Terumi, Takeda, Kazunori, Mayumi, Toshihiko, Kitagawa, Motoji, Ito, Tetsuhide, Inui, Kazuo, Shimosegawa, Tooru, Tanaka, Shigeki, Kataoka, Keisho, Saisho, Hiromitsu, Okazaki, Kazuichi, Kuroda, Yosikazu, Sawabu, Norio, Takeyama, Yoshifumi

“…The incidence of acute pancreatitis in Japan is increasing and ranges from 187 to 347 cases per million populations. Case fatality was 0.2% for mild to…”
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Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma by Jiang, PeiHong, Watanabe, Hiroyuki, Okada, Gensaku, Ohtsubo, Koushiro, Mouri, Hisatsugu, Tsuchiyama, Tomoya, Yao, Fan, Sawabu, Norio

“…The tissue factor pathway inhibitor 2 (TFPI‐2) is a Kunitz‐type serine proteinase inhibitor. Recently, the aberrant methylation of TFPI‐2 was detected…”
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Expression of Clusterin in human pancreatic cancer by XIE, Min-Jue, MOTOO, Yoshiharu, SU, Shi-Bing, MOURI, Hisatsugu, OHTSUBO, Koushiro, MATSUBARA, Fujitsugu, SAWABU, Norio

“…Clusterin, also known as apolipoprotein J, has been implicated in numerous processes, including active cell death. Clusterin is reported to be overexpressed in…”
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Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines by Motoo, Y, Sawabu, N

“…Antitumor effects of nine components of a herbal medicine, 'Sho-saiko-to', were investigated on human hepatoma cell lines (PLC/PRF/5, Hep-G2), human liver…”
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Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: immunohistochemical and genetic findings compared with clinicopathological parameters by Ohtsubo, Koushiro, Watanabe, Hiroyuki, Yamaguchi, Yasushi, Hu, Yu-Xin, Motoo, Yoshiharu, Okai, Takashi, Sawabu, Norio

“…Abnormalities of the tumor suppressor gene p16 have been reported in a variety of human tumors but are rare in pancreatic carcinoma except for cancer cell…”
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Preproenkephalin hypermethylation in the pure pancreatic juice compared with p53 mutation in the diagnosis of pancreatic carcinoma by Ohtsubo, Koushiro, Watanabe, Hiroyuki, Yao, Fan, Okada, Gensaku, Mouri, Hisatsugu, Yamaguchi, Yasushi, Sawabu, Norio

“…Aberrant methylation of CpG islands is a common mechanism for the dysregulation of tumor suppressor genes in a variety of human malignancies. Preproenkephalin…”
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Herbal medicine Ninjinyoeito ameliorates ribavirin-induced anemia in chronic hepatitis C: a randomized controlled trial by Motoo, Yoshiharu, Mouri, Hisatsugu, Ohtsubo, Koushiro, Yamaguchi, Yasushi, Watanabe, Hiroyuki, Sawabu, Norio

“…Ribavirin (RBV) shows a strong antiviral effect on hepatitis C virus when used in combination with interferon. However, RBV-induced anemia is a major problem…”
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Clinical study of chronic pancreatitis with focal irregular narrowing of the Main pancreatic duct and mass formation: Comparison with chronic pancreatitis showing diffuse irregular narrowing of the main pancreatic duct by WAKABAYASHI, Tokio, KAWAURA, Yukimitsu, SATOMURA, Yoshitake, FUJII, Tomoharu, MOTOO, Yoshiharu, OKAI, Takashi, SAWABU, Norio

“…Main pancreatic duct (MPD)-narrowed chronic pancreatitis (CP) may be an autoimmune abnormality. It also has been called autoimmune pancreatitis and sclerosing…”
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A pilot study of individualized maximum repeatable dose (iMRD), a new dose finding system, of weekly gemcitabine for patients with metastatic pancreas cancer by Takahashi, Yutaka, Mai, Masayoshi, Sawabu, Norio, Nishioka, Kenji

“…We developed and established a new dose-finding system, the individualized maximum repeatable dose (iMRD), suitable to induce prolonged TTP rather than tumor…”
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Overexpression of p8 Is Inversely Correlated with Apoptosis in Pancreatic Cancer by SU, Shi-Bing, MOTOO, Yoshiharu, IOVANNA, Juan Lucio, BERTHEZENE, Patrice, XIE, Min-Jue, MOURI, Hisatsugu, OHTSUBO, Koushiro, MATSUBARA, Fujitsugu, SAWABU, Norio

“…A recently identified gene, p8 , has cell growth-promoting activity and is strongly induced in acute pancreatitis. In this study, we detected p8 and…”
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Clinical management of Intraductal papillary mucinous tumors of the pancreas based on imaging findings by WAKABAYASHI, Tokio, KAWAURA, Yukimitsu, MORIMOTO, Hideo, WATANABE, Kishichiroh, TOYA, Daishyu, ASADA, Yasuyuki, SATOMURA, Yoshitake, WATANABE, Hiroyuki, OKAI, Takashi, SAWABU, Norio

“…The aim of this study was to assess the imaging findings of pathologically proven intraductal papillary-mucinous tumors of the pancreas and the natural history…”
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Detection of Mutations of p53 Tumor Suppressor Gene in Pancreatic Juice and Its Application to Diagnosis of Patients with Pancreatic Cancer: Comparison with K-ras Mutation by YAMAGUCHI, Y, WATANABE, H, YRDIRAN, S, OHTSUBO, K, MOTOO, Y, OKAI, T, SAWABU, N

“…Because of the difficulty in obtaining biopsy specimens from pancreatic cancer patients, K- ras mutation analysis in pancreatic juice has been used for…”
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Detection of p53 gene mutations in the supernatant of pancreatic juice and plasma from patients with pancreatic carcinomas by Wang, Ying, Yamaguchi, Yasushi, Watanabe, Hiroyuki, Ohtsubo, Koushirou, Motoo, Yoshiharu, Sawabu, Norio

“…The sensitivity of pure pancreatic juice (PPJ) cytology for the diagnosis of pancreatic carcinoma (PCa) is still low. The usefulness of genetic analyses of PPJ…”
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Expression of p8 in Human Pancreatic Cancer by SU, Shi-Bing, MOTOO, Yoshiharu, SAWABU, Norio, IOVANNA, Juan Lucio, XIE, Min-Jue, MOURI, Hisatsugu, OHTSUBO, Koushiro, YAMAGUCHI, Yasushi, WATANABE, Hiroyuki, OKAI, Takashi, MATSUBARA, Fujitsugu

“…The p8 gene is a recently identified gene with mitogenic activity. p8 expression is induced in acute pancreatitis, pancreatic development, and regeneration…”
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