Search Results - "Sawa, A."
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Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry
Published in Molecular psychiatry (01-01-2018)“…A great deal of interest in psychiatric research is currently centered upon the pathogenic role of inflammatory processes. Positron emission tomography (PET)…”
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Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia
Published in Molecular psychiatry (01-02-2018)“…Positron emission tomography (PET) imaging with radiotracers that target translocator protein 18 kDa (TSPO) has become a popular approach to assess putative…”
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Spike-shape dependence of the spike-timing dependent synaptic plasticity in ferroelectric-tunnel-junction synapses
Published in Scientific reports (28-11-2019)“…Resistive switching (RS) devices have attracted increasing attention for artificial synapse applications in neural networks because of their nonvolatile and…”
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Hysteretic current–voltage characteristics and resistance switching at a rectifying Ti∕Pr0.7Ca0.3MnO3 interface
Published in Applied physics letters (01-11-2004)“…We have characterized the vertical transport properties of epitaxial layered structures composed of Pr0.7Ca0.3MnO3(PCMO) sandwiched between SrRuO3(SRO) bottom…”
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Molecular substrates of schizophrenia: homeostatic signaling to connectivity
Published in Molecular psychiatry (01-01-2016)“…Schizophrenia (SZ) is a devastating psychiatric condition affecting numerous brain systems. Recent studies have identified genetic factors that confer an…”
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Utility and validity of DISC1 mouse models in biological psychiatry
Published in Neuroscience (03-05-2016)“…Highlights • Multiple DISC1 models have been generated, but can be organized into three categories. • DISC1 models are useful in their biological and face…”
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Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice
Published in Molecular psychiatry (01-08-2018)“…Dopamine in prefrontal cortices is implicated in cognitive and emotional functions, and the dysfunction of prefrontal dopamine has been associated with…”
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Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion
Published in Molecular psychiatry (01-05-2013)“…Perturbation of Disrupted-In-Schizophrenia-1 (DISC1) and D -serine/NMDA receptor hypofunction have both been implicated in the pathophysiology of schizophrenia…”
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Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application
Published in Translational psychiatry (21-01-2014)“…Bipolar disorder (BD) is a debilitating mental illness characterized by severe fluctuations in mood, sleep, energy and executive functioning. Pharmacological…”
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Hysteretic current–voltage characteristics and resistance switching at an epitaxial oxide Schottky junction SrRuO3∕SrTi0.99Nb0.01O3
Published in Applied physics letters (03-01-2005)“…Transport properties have been studied for a perovskite heterojunction consisting of SrRuO3 (SRO) film epitaxially grown on SrTi0.99Nb0.01O3 (Nb:STO)…”
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Probing ultrafast spin-relaxation and precession dynamics in a cuprate Mott insulator with seven-femtosecond optical pulses
Published in Nature communications (26-09-2018)“…A charge excitation in a two-dimensional Mott insulator is strongly coupled with the surrounding spins, which is observed as magnetic-polaron formations of…”
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In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [11C]DPA-713 PET and analysis of CSF and plasma
Published in Translational psychiatry (12-04-2016)“…Several lines of evidence suggest aberrant immune response in schizophrenia, including elevated levels of cytokines. These cytokines are thought to be produced…”
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Interface resistance switching at a few nanometer thick perovskite manganite active layers
Published in Applied physics letters (05-06-2006)“…We have studied the transport and resistance switching properties of Ti ∕ Sm 0.7 Ca 0.3 Mn O 3 ( n unit cells)/ La 0.7 Sr 0.3 Mn O 3 [ Ti ∕ SCMO ( n ) ∕ LSMO ]…”
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DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1
Published in Molecular psychiatry (01-11-2016)Get full text
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Studying schizophrenia in the post-genomic era: perspectives from the 2016 summer Banbury Workshop at Cold Spring Harbor Laboratory
Published in Molecular psychiatry (01-01-2017)Get full text
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Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders
Published in Molecular psychiatry (01-03-2011)“…Strong genetic evidence implicates mutations and polymorphisms in the gene Disrupted-In-Schizophrenia-1 ( DISC1 ) as risk factors for both schizophrenia and…”
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DISC1–ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1
Published in Molecular psychiatry (01-08-2013)“…Disrupted-In-Schizophrenia 1 ( DISC1 ), a risk factor for major mental illnesses, has been studied extensively in the context of neurodevelopment. However, the…”
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Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry
Published in Translational psychiatry (22-08-2017)“…The establishment of mechanism-driven peripheral markers is important for translational psychiatry. Many groups, including ours, have addressed molecular…”
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Identifying canonical and replicable multi-scale intrinsic connectivity networks in 100k+ resting-state fMRI datasets
Published in Human brain mapping (01-12-2023)“…Despite the known benefits of data-driven approaches, the lack of approaches for identifying functional neuroimaging patterns that capture both individual…”
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