Search Results - "Savvateeva, Lyudmila V."

Nanomedicine for increasing the oral bioavailability of cancer treatments by Parodi, Alessandro, Buzaeva, Polina, Nigovora, Daria, Baldin, Alexey, Kostyushev, Dmitry, Chulanov, Vladimir, Savvateeva, Lyudmila V, Zamyatnin, Jr, Andrey A

“…Oral administration is an appealing route of delivering cancer treatments. However, the gastrointestinal tract is characterized by specific and efficient…”
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Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting by Baldin, Alexey V, Savvateeva, Lyudmila V, Bazhin, Alexandr V, Zamyatnin, Jr, Andrey A

“…Dendritic cells (DCs) have shown great potential as a component or target in the landscape of cancer immunotherapy. Different in vivo and ex vivo strategies of…”
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Intrinsically Connected: Therapeutically Targeting the Cathepsin Proteases and the Bcl-2 Family of Protein Substrates as Co-regulators of Apoptosis by Soond, Surinder M, Kozhevnikova, Maria V, Savvateeva, Lyudmila V, Townsend, Paul A, Zamyatnin, Jr, Andrey A

“…Taken with the growing importance of cathepsin-mediated substrate proteolysis in tumor biology and progression, the focus and emphasis placed on therapeutic…”
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Prospects of Developing Medicinal Therapeutic Strategies and Pharmaceutical Design for Effective Gluten Intolerance Treatment by Savvateeva, Lyudmila V, Zamyatnin, Andrey A

“…Gluten intolerance is an umbrella term for gluten-related disorders manifested in health decline as a result of the gluten ingestion. The spectrum of…”
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Structure determinants defining the specificity of papain-like cysteine proteases by Petushkova, Anastasiia I., Savvateeva, Lyudmila V., Zamyatnin, Andrey A.

“…[Display omitted] Papain-like cysteine proteases are widely expressed enzymes that mostly regulate protein turnover in the acidic conditions of lysosomes…”
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Unveiling the Roles of Cysteine Proteinases F and W: From Structure to Pathological Implications and Therapeutic Targets by Zdravkova, Kristina, Mijanovic, Olja, Brankovic, Ana, Ilicheva, Polina M, Jakovleva, Aleksandra, Karanovic, Jelena, Pualic, Milena, Pualic, Dusan, Rubel, Aleksandr A, Savvateeva, Lyudmila V, Parodi, Alessandro, Zamyatnin, Jr, Andrey A

“…Cysteine cathepsins F and W are members of the papain-like cysteine protease family, which have distinct structural features and functional roles in various…”
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Cathepsin S Cleaves BAX as a Novel and Therapeutically Important Regulatory Mechanism for Apoptosis by Soond, Surinder M, Savvateeva, Lyudmila V, Makarov, Vladimir A, Gorokhovets, Neonila V, Townsend, Paul A, Zamyatnin, Jr, Andrey A

“…Certain lysosomal cathepsin proteins have come into focus as being good candidates for therapeutic targeting, based on them being over-expressed in a variety…”
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Current Paediatric Coeliac Disease Screening Strategies and Relevance of Questionnaire Survey by Savvateeva, Lyudmila V, Erdes, Svetlana I, Antishin, Anton S, Zamyatnin, Jr, Andrey A

“…Coeliac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten-containing grains in genetically predisposed individuals. Identification…”
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Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence by Zamyatnin, Andrey A., Antishin, Anton S., Erdes, Svetlana I., Savvateeva, Lyudmila V.

“…Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of dietary gluten from some cereals mainly in individuals carrying the HLA-DQ2…”
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Lost or Forgotten: The nuclear cathepsin protein isoforms in cancer by Soond, Surinder M., Kozhevnikova, Maria V., Frolova, Anastasia S., Savvateeva, Lyudmila V., Plotnikov, Egor Y., Townsend, Paul A., Han, Yuan-Ping, Zamyatnin, Andrey A.

“…While research into the role of cathepsins has been progressing at an exponential pace over the years, research into their respective isoform proteins has been…”
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Evaluation of molecular mechanisms of riboflavin anti-COVID-19 action reveals anti-inflammatory efficacy rather than antiviral activity by Akasov, Roman A., Chepikova, Olga E., Pallaeva, Tatiana N., Gorokhovets, Neonila V., Siniavin, Andrei E., Gushchin, Vladimir A., Savvateeva, Lyudmila V., Vinokurov, Ivan A., Khochenkov, Dmitry A., Zamyatnin, Andrey A., Khaydukov, Evgeny V.

“…Riboflavin (vitamin B2) is one of the most important water-soluble vitamins and a coenzyme involved in many biochemical processes. It has previously been shown…”
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Current Status and Perspectives of Protease Inhibitors and Their Combination with Nanosized Drug Delivery Systems for Targeted Cancer Therapy by Rudzińska, Magdalena, Daglioglu, Cenk, Savvateeva, Lyudmila V, Kaci, Fatma Necmiye, Antoine, Rodolphe, Zamyatnin, Jr, Andrey A

“…In cancer treatments, many natural and synthetic products have been examined; among them, protease inhibitors are promising candidates for anti-cancer agents…”
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Making Connections: p53 and the Cathepsin Proteases as Co-Regulators of Cancer and Apoptosis by Soond, Surinder M., Savvateeva, Lyudmila V., Makarov, Vladimir A., Gorokhovets, Neonila V., Townsend, Paul A., Zamyatnin, Andrey A.

“…While viewed as the “guardian of the genome”, the importance of the tumor suppressor p53 protein has increasingly gained ever more recognition in modulating…”
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Novel applications of modification of thiol enzymes and redox-regulated proteins using S-methyl methanethiosulfonate (MMTS) by Makarov, Vladimir A., Tikhomirova, Natalia K., Savvateeva, Lyudmila V., Petushkova, Anastasiia I., Serebryakova, Marina V., Baksheeva, Viktoriia E., Gorokhovets, Neonila V., Zernii, Evgeni Yu, Zamyatnin, Andrey A.

“…S-Methyl methanethiosulfonate (MMTS) is used in experimental biochemistry for alkylating thiol groups of protein cysteines. Its applications include mainly…”
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Glutenase and collagenase activities of wheat cysteine protease Triticain-α: Feasibility for enzymatic therapy assays by Savvateeva, Lyudmila V., Gorokhovets, Neonila V., Makarov, Vladimir A., Serebryakova, Marina V., Solovyev, Andrey G., Morozov, Sergey Yu, Reddy, V. Prakash, Zernii, Evgeni Yu, Zamyatnin, Andrey A., Aliev, Gjumrakch

“…Insufficient and/or improper protein degradation is associated with the development of various human pathologies. Enzymatic therapy with proteolytic enzymes…”
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Autoantibody against arrestin-1 as a potential biomarker of renal cell carcinoma by Baldin, Alexey V., Grishina, Alena N., Korolev, Dmitry O., Kuznetsova, Ekaterina B., Golovastova, Marina O., Kalpinskiy, Alexey S., Alekseev, Boris Y., Kaprin, Andrey D., Zinchenko, Dmitry V., Savvateeva, Lyudmila V., Varshavsky, Vladimir A., Zernii, Evgeni Yu, Vinarov, Andrey Z., Bazhin, Alexandr V., Philippov, Pavel P., Zamyatnin, Andrey A.

“…Renal cell carcinoma (RCC) is the second-most common uronephrological cancer. In the absence of specific symptoms, early diagnosis of RCC is challenging…”
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Rational Design of Recombinant Papain-Like Cysteine Protease: Optimal Domain Structure and Expression Conditions for Wheat-Derived Enzyme Triticain-α by Gorokhovets, Neonila V, Makarov, Vladimir A, Petushkova, Anastasiia I, Prokopets, Olga S, Rubtsov, Mikhail A, Savvateeva, Lyudmila V, Zernii, Evgeni Yu, Zamyatnin, Jr, Andrey A

“…Triticain-α is a papain-like cysteine protease from wheat ( L.) that possesses activity towards toxic gluten-derived peptides, and was thus proposed as a novel…”
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The cancer-retina antigen recoverin as a potential biomarker for renal tumors by Golovastova, Marina O., Tsoy, Larisa V., Bocharnikova, Anna V., Korolev, Dmitry O., Gancharova, Olga S., Alekseeva, Ekaterina A., Kuznetsova, Ekaterina B., Savvateeva, Lyudmila V., Skorikova, Elena E., Strelnikov, Vladimir V., Varshavsky, Vladimir A., Vinarov, Andrey Z., Nikolenko, Vladimir N., Glybochko, Peter V., Zernii, Evgeni Yu, Zamyatnin, Andrey A., Bazhin, Alexandr V., Philippov, Pavel P.

“…The renal cell carcinoma is the ninth most common cancer with an increasing occurrence and mortality. Recoverin is the first retina-specific photoreceptor…”
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Questionnaire‐based survey to determine an at‐risk group for coeliac disease among school children in Moscow, Russia by Antishin, Anton S, Erdes, Svetlana I, Savvateeva, Lyudmila V, Soond, Surinder M, Zamyatnin, Andrey A

“…Aim Coeliac disease (CD) is a chronic digestive disorder which presents in diverse ways and is under‐diagnosed. The purpose of this study was to provide…”
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