Search Results - "Savu, Diana"

Role of mesoporous silica functionalized with boronic acid derivative in targeted delivery of doxorubicin and co-delivery of doxorubicin and resveratrol by Ioniță, Simona, Popescu, Roxana-Cristina, Irimescu, Ionela Nicoleta, Deaconu, Mihaela, Tarbă, Nicolae, Matei, Cristian, Mihailescu, Mona, Savu, Diana-Iulia, Berger, Daniela

“…Phenylboronic acid derivatives have gained interest due to their ability to reversibly bind to 1,2-diols, such as sialic acid receptors overexpressed by breast…”
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Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors by Rødland, Gro Elise, Temelie, Mihaela, Eek Mariampillai, Adrian, Hauge, Sissel, Gilbert, Antoine, Chevalier, François, Savu, Diana I, Syljuåsen, Randi G

“…The use of charged particle radiotherapy is currently increasing, but combination therapy with DNA repair inhibitors remains to be exploited in the clinic. The…”
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Electrically Triggered Drug Delivery from Novel Electrospun Poly(Lactic Acid)/Graphene Oxide/Quercetin Fibrous Scaffolds for Wound Dressing Applications by Croitoru, Alexa-Maria, Karaçelebi, Yasin, Saatcioglu, Elif, Altan, Eray, Ulag, Songul, Aydoğan, Huseyin Kıvanc, Sahin, Ali, Motelica, Ludmila, Oprea, Ovidiu, Tihauan, Bianca-Maria, Popescu, Roxana-Cristina, Savu, Diana, Trusca, Roxana, Ficai, Denisa, Gunduz, Oguzhan, Ficai, Anton

“…The novel controlled and localized delivery of drug molecules to target tissues using an external electric stimulus makes electro-responsive drug delivery…”
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Radiofrequency EMF irradiation effects on pre-B lymphocytes undergoing somatic recombination by Ioniţă, Elena, Marcu, Aurelian, Temelie, Mihaela, Savu, Diana, Şerbănescu, Mihai, Ciubotaru, Mihai

“…Intense electromagnetic fields (EMFs) induce DNA double stranded breaks (DSBs) in exposed lymphocytes.We study developing pre-B lymphocytes following V(D)J…”
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A Proteomic Study Suggests Stress Granules as New Potential Actors in Radiation-Induced Bystander Effects by Tudor, Mihaela, Gilbert, Antoine, Lepleux, Charlotte, Temelie, Mihaela, Hem, Sonia, Armengaud, Jean, Brotin, Emilie, Haghdoost, Siamak, Savu, Diana, Chevalier, François

“…Besides the direct effects of radiations, indirect effects are observed within the surrounding non-irradiated area; irradiated cells relay stress signals in…”
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Nanoparticle-Mediated Drug Delivery of Doxorubicin Induces a Differentiated Clonogenic Inactivation in 3D Tumor Spheroids In Vitro by Popescu, Roxana Cristina, Kopatz, Verena, Andronescu, Ecaterina, Savu, Diana Iulia, Doerr, Wolfgang

“…Involvement of 3D tumor cell models in the in vitro biological testing of novel nanotechnology-based strategies for cancer management can provide in-depth…”
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High LET Radiation Overcomes In Vitro Resistance to X-Rays of Chondrosarcoma Cell Lines by Chevalier, Francois, Hamdi, Dounia Houria, Lepleux, Charlotte, Temelie, Mihaela, Nicol, Anaïs, Austry, Jean Baptiste, Lesueur, Paul, Vares, Guillaume, Savu, Diana, Nakajima, Tetsuo, Saintigny, Yannick

“…Chondrosarcomas are malignant tumors of the cartilage that are chemoresistant and radioresistant to X-rays. This restricts the treatment options essential to…”
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RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice by Mustăciosu, Cosmin Cătălin, Banciu, Adela, Rusu, Călin Mircea, Banciu, Daniel Dumitru, Savu, Diana, Radu, Mihai, Radu, Beatrice Mihaela

“…The neuron-specific -like Hu RNA-binding proteins were described to play an important role in neuronal differentiation and plasticity by ensuring the…”
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Novel Graphene Oxide/Quercetin and Graphene Oxide/Juglone Nanostructured Platforms as Effective Drug Delivery Systems with Biomedical Applications by Croitoru, Alexa-Maria, Moroșan, Alina, Tihăuan, Bianca, Oprea, Ovidiu, Motelică, Ludmila, Trușcă, Roxana, Nicoară, Adrian Ionuț, Popescu, Roxana-Cristina, Savu, Diana, Mihăiescu, Dan Eduard, Ficai, Anton

“…In this paper, novel drug delivery systems (DDS) were designed based on graphene oxide (GO) as nanocarrier, loaded with two natural substances (quercetin (Qu)…”
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3D Printing of Alginate-Natural Clay Hydrogel-Based Nanocomposites by Leu Alexa, Rebeca, Ianchis, Raluca, Savu, Diana, Temelie, Mihaela, Trica, Bogdan, Serafim, Andrada, Vlasceanu, George Mihail, Alexandrescu, Elvira, Preda, Silviu, Iovu, Horia

“…Biocompatibility, biodegradability, shear tinning behavior, quick gelation and an easy crosslinking process makes alginate one of the most studied…”
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Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes by Lepleux, Charlotte, Marie-Brasset, Aurélie, Temelie, Mihaela, Boulanger, Marion, Brotin, Émilie, Goldring, Mary B., Hirtz, Christophe, Varès, Guillaume, Nakajima, Tetsuo, Saintigny, Yannick, Savu, Diana, Chevalier, François

“…While the dose-response relationship of radiation-induced bystander effect (RIBE) is controversial at low and high linear energy transfer (LET), mechanisms and…”
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Fabrication, Characterization, and Evaluation of Bionanocomposites Based on Natural Polymers and Antibiotics for Wound Healing Applications by Rădulescu, Marius, Holban, Alina Maria, Mogoantă, Laurențiu, Bălşeanu, Tudor-Adrian, Mogoșanu, George Dan, Savu, Diana, Popescu, Roxana Cristina, Fufă, Oana, Grumezescu, Alexandru Mihai, Bezirtzoglou, Eugenia, Lazar, Veronica, Chifiriuc, Mariana Carmen

“…The aim of our research activity was to obtain a biocompatible nanostructured composite based on naturally derived biopolymers (chitin and sodium alginate)…”
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Specific spectral sub-images for machine learning evaluation of optical differences between carbon ion and X ray radiation effects by Negoita, Raluca D., Ilisanu, Mihaela A., Irimescu, Ionela N., Popescu, Roxana C., Tudor, Mihaela, Mihailescu, Mona, Scarlat, Eugen N., Pleava, Ana M., Dinischiotu, Anca, Savu, Diana

“…Advances in radiotherapy, particularly the exploration of alternative radiation types such as carbon ions have updated our understanding of its effects and…”
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Laser Processed Antimicrobial Nanocomposite Based on Polyaniline Grafted Lignin Loaded with Gentamicin-Functionalized Magnetite by Visan, Anita Ioana, Popescu-Pelin, Gianina, Gherasim, Oana, Grumezescu, Valentina, Socol, Marcela, Zgura, Irina, Florica, Camelia, Popescu, Roxana C, Savu, Diana, Holban, Alina Maria, Cristescu, Rodica, Matei, Consuela E, Socol, Gabriel

“…Composite thin coatings of conductive polymer (polyaniline grafted lignin, PANI-LIG) embedded with aminoglycoside Gentamicin sulfate (GS) or magnetite…”
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Impaired Integrated Stress Response and Mitochondrial Integrity Modulate Genotoxic Stress Impact and Lower the Threshold for Immune Signalling by Temelie, Mihaela, Talpur, Rubab, Dominguez-Prieto, Marta, Dantas Silva, Ayanda, Cenusa, Constantin, Craciun, Liviu, Savu, Diana Iulia, Moisoi, Nicoleta

“…Mitochondria-nucleus communication during stress dictates cellular fate with consequences on the etiopathology of multiple age-related diseases. Impaired…”
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Bystander effects and compartmental stress response to X-ray irradiation in L929 cells by Temelie, Mihaela, Stroe, Daniela, Petcu, Ileana, Mustaciosu, Cosmin, Moisoi, Nicoleta, Savu, Diana

“…Bystander effects are indirect consequences of radiation and many other stress factors. They occur in cells that are not directly exposed to these factors, but…”
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In vitro hyperspectral biomarkers of human chondrosarcoma cells in nanoparticle-mediated radiosensitization using carbon ions by Tudor, Mihaela, Popescu, Roxana Cristina, Negoita, Raluca D., Gilbert, Antoine, Ilisanu, Mihaela A., Temelie, Mihaela, Dinischiotu, Anca, Chevalier, François, Mihailescu, Mona, Savu, Diana Iulia

“…New therapeutic approaches are needed for the management of the highly chemo- and radioresistant chondrosarcoma (CHS). In this work, we used polyethylene…”
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Novel Antitumor Agents Based on Fluorescent Benzofurazan Derivatives and Mesoporous Silica by Tudose, Madalina, Culita, Daniela C, Baratoiu-Carpen, Rodica D, Mitran, Raul-Augustin, Kuncser, Andrei, Romanitan, Cosmin, Popescu, Roxana Cristina, Savu, Diana Iulia

“…Two novel fluorescent mesoporous silica-based hybrid materials were obtained through the covalent grafting of [4-hydrazinyl-7-nitrobenz-[2,1,3- ]-oxadiazole…”
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Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells by Popescu, Roxana Cristina, Savu, Diana Iulia, Bierbaum, Miriam, Grbenicek, Adriana, Schneider, Frank, Hosser, Hiltraud, Vasile, Bogdan Ștefan, Andronescu, Ecaterina, Wenz, Frederik, Giordano, Frank A., Herskind, Carsten, Veldwijk, Marlon R.

“…In this study, we determined the potential of polyethylene glycol-encapsulated iron oxide nanoparticles (IONPCO) for the intracellular delivery of the…”
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Development of New Collagen/Clay Composite Biomaterials by Marin, Maria Minodora, Ianchis, Raluca, Leu Alexa, Rebeca, Gifu, Ioana Catalina, Kaya, Madalina Georgiana Albu, Savu, Diana Iulia, Popescu, Roxana Cristina, Alexandrescu, Elvira, Ninciuleanu, Claudia Mihaela, Preda, Silviu, Ignat, Madalina, Constantinescu, Roxana, Iovu, Horia

“…The fabrication of collagen-based biomaterials for skin regeneration offers various challenges for tissue engineers. The purpose of this study was to obtain a…”
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