Search Results - "Savov, J"

Subchronic endotoxin inhalation causes persistent airway disease by Brass, D M, Savov, J D, Gavett, S H, Haykal-Coates, N, Schwartz, D A

“…The endotoxin component of organic dusts causes acute reversible airflow obstruction and airway inflammation. To test the hypothesis that endotoxin alone…”
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LPS binding protein is important in the airway response to inhaled endotoxin by Brass, David M., Savov, Jordan D., Whitehead, Gregory S., Maxwell, Abby B., Schwartz, David A.

“…Inhaled endotoxin is a risk factor for asthma exacerbation, and endotoxin inhalation by itself recapitulates many of the classical features of asthma in mice,…”
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Intercellular adhesion molecule-1 plays a pivotal role in endotoxin-induced airway disease by Brass, David M, Savov, Jordan D, Schwartz, David A

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Bilateral persistent complete sciatic artery by Savov, Jordan D., Wassilev, Wassil A.

“…A case with persistent sciatic artery (PSA) was found in a cadaver of a 65‐year‐old female during a medical gross anatomy course. The artery was bilateral and…”
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Immobilization and ultrastructure of alveolar type II cells by Kovacheva-Ivanova, S, Savov, J

“…We studied the ultrastructural changes in the alveolar type II cells from the lung of immobilized male Wistar rats divided into 6 groups: control; immobilized…”
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Surfactant Protein D Stimulates Phagocytosis of Pseudomonas aeruginosa by Alveolar Macrophages by Restrepo, Clara I, Dong, Qun, Savov, Jordan, Mariencheck, William I, Wright, Jo Rae

“…Surfactant protein (SP)-D is an oligomeric glycoprotein belonging to the family of collagen-like lectins known as collectins, which have previously been shown…”
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Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa by Mariencheck, W I, Savov, J, Dong, Q, Tino, M J, Wright, J R

“…In this study, we investigate the interaction between surfactant protein A (SP-A) and a live, mucoid strain of Pseudomonas aeruginosa and identify a mechanism…”
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Beta-arrestin-2 regulates the development of allergic asthma by Walker, Julia K L, Fong, Alan M, Lawson, Barbara L, Savov, Jordan D, Patel, Dhavalkumar D, Schwartz, David A, Lefkowitz, Robert J

“…Asthma is a chronic inflammatory disorder of the airways that is coordinated by Th2 cells in both human asthmatics and animal models of allergic asthma…”
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Binding and uptake of surfactant protein D by freshly isolated rat alveolar type II cells by Herbein, J F, Savov, J, Wright, J R

“…Alveolar type II cells secrete, internalize, and recycle pulmonary surfactant, a lipid and protein complex that increases alveolar compliance and participates…”
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Mechanical ventilation of rat lung: effect on surfactant forms by Savov, J, Silbajoris, R, Young, S L

“…Mechanical ventilation of the lung could affect surfactant turnover by alteration of its secretion, recycling, and degradation. In vitro studies of surfactant…”
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Incorporation of biotinylated SP-A into rat lung surfactant layer, type II cells, and clara cells by Savov, J, Wright, J R, Young, S L

“…The goal of this study was to compare the functions of Clara and type II cells during alveolar clearance and recycling of surfactant protein (SP) A, a…”
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Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide by Savov, Jordan D, Brass, David M, Lawson, Barbara L, McElvania-Tekippe, Erin, Walker, Julia K L, Schwartz, David A

“…Although chronic inhalation of endotoxin or lipopolysaccharide (LPS) causes all of the classic features of asthma, including airway hyperreactivity, airway…”
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Ozone-Induced Acute Pulmonary Injury in Inbred Mouse Strains by Savov, Jordan D, Whitehead, Gregory S, Wang, Jianme, Liao, Guochun, Usuka, Jonathan, Peltz, Gary, Foster, W. Michael, Schwartz, David A

“…To determine if host factors influence the time course and extent of lung injury after acute inhalation of ozone (O3), we evaluated the physiologic and…”
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Neutrophils play a critical role in development of LPS-induced airway disease by Savov, Jordan D, Gavett, Stephen H, Brass, David M, Costa, Daniel L, Schwartz, David A

“…We investigated the role of neutrophils in the development of endotoxin-induced airway disease via systemic neutrophil depletion of C3H/HeBFeJ mice and…”
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Fibrinolysis in LPS-induced chronic airway disease by Savov, Jordan D, Brass, David M, Berman, Katherine G, McElvania, Erin, Schwartz, David A

“…To examine the role of the fibrinolytic system in LPS-induced airway disease, we compared the effect of a chronic LPS challenge in plasminogen activator…”
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