Search Results - "Savli, Markus"

Normative database of the serotonergic system in healthy subjects using multi-tracer PET by Savli, Markus, Bauer, Andreas, Mitterhauser, Markus, Ding, Yu-Shin, Hahn, Andreas, Kroll, Tina, Neumeister, Alexander, Haeusler, Daniela, Ungersboeck, Johanna, Henry, Shannan, Isfahani, Sanaz Attaripour, Rattay, Frank, Wadsak, Wolfgang, Kasper, Siegfried, Lanzenberger, Rupert

“…The highly diverse serotonergic system with at least 16 different receptor subtypes is implicated in the pathophysiology of most neuropsychiatric disorders…”
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Challenges in the differentiation of midbrain raphe nuclei in neuroimaging research by Kranz, Georg S, Hahn, Andreas, Savli, Markus, Lanzenberger, Rupert

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Gray matter and intrinsic network changes in the posterior cingulate cortex after selective serotonin reuptake inhibitor intake by Kraus, Christoph, Ganger, Sebastian, Losak, Jan, Hahn, Andreas, Savli, Markus, Kranz, Georg S., Baldinger, Pia, Windischberger, Christian, Kasper, Siegfried, Lanzenberger, Rupert

“…Preclinical studies have demonstrated that serotonin (5-HT) challenge changes neuronal circuitries and microarchitecture. However, evidence in human subjects…”
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Attenuated serotonin transporter association between dorsal raphe and ventral striatum in major depression by Hahn, Andreas, Haeusler, Daniela, Kraus, Christoph, Höflich, Anna S., Kranz, Georg S., Baldinger, Pia, Savli, Markus, Mitterhauser, Markus, Wadsak, Wolfgang, Karanikas, Georgios, Kasper, Siegfried, Lanzenberger, Rupert

“…Suffering from anhedonia, patients with major depressive disorder (MDD) exhibit alterations in several parts of the serotonergic neurotransmitter system, which…”
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Aggression is related to frontal serotonin-1A receptor distribution as revealed by PET in healthy subjects by Witte, A. Veronica, Flöel, Agnes, Stein, Patrycja, Savli, Markus, Mien, Leonhard-Key, Wadsak, Wolfgang, Spindelegger, Christoph, Moser, Ulrike, Fink, Martin, Hahn, Andreas, Mitterhauser, Markus, Kletter, Kurt, Kasper, Siegfried, Lanzenberger, Rupert

“…Objectives: Various studies indicate that serotonin regulates impulsivity and the inhibitory control of aggression. Aggression is also known to be modified by…”
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Serotonin and molecular neuroimaging in humans using PET by Saulin, Anne, Savli, Markus, Lanzenberger, Rupert

“…The serotonergic system is one of the most important modulatory neurotransmitter systems in the human brain. It plays a central role in major physiological…”
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Regional sex differences in grey matter volume are associated with sex hormones in the young adult human brain by Witte, A. Veronica, Savli, Markus, Holik, Alexander, Kasper, Siegfried, Lanzenberger, Rupert

“…Previous studies suggest organizing effects of sex hormones on brain structure during early life and puberty, yet little is known about the adult period. The…”
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High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People by Kranz, Georg S, Wadsak, Wolfgang, Kaufmann, Ulrike, Savli, Markus, Baldinger, Pia, Gryglewski, Gregor, Haeusler, Daniela, Spies, Marie, Mitterhauser, Markus, Kasper, Siegfried, Lanzenberger, Rupert

“…Abstract Background Women are two times more likely to be diagnosed with depression than men. Sex hormones modulating serotonergic transmission are proposed to…”
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A novel formulation of budesonide nasal spray (Budesolv 10) potentiates clinical performance in grass pollen allergic patients by Zieglmayer, isabel, Schmutz, René, Lemell, Patrick, Unger-Manhart, Nicole, Nakowitsch, Sabine, Goessl, Andreas, Savli, Markus, Zieglmayer, René, Prieschl-Grassauer, Eva

“…Abstract Objective Purpose of this DBPC study was to evaluate onset of action and non-inferiority of a novel low dose aqueous solution of Budesonide (“Budesolv…”
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Prediction of SSRI treatment response in major depression based on serotonin transporter interplay between median raphe nucleus and projection areas by Lanzenberger, Rupert, Kranz, Georg S., Haeusler, Daniela, Akimova, Elena, Savli, Markus, Hahn, Andreas, Mitterhauser, Markus, Spindelegger, Christoph, Philippe, Cecile, Fink, Martin, Wadsak, Wolfgang, Karanikas, Georgios, Kasper, Siegfried

“…Recent mathematical models suggest restored serotonergic burst-firing to underlie the antidepressant effect of selective serotonin reuptake inhibitors (SSRI),…”
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Fast effectiveness of a solubilized low‐dose budesonide nasal spray in allergic rhinitis by Zieglmayer, Petra, Schmutz, René, Lemell, Patrick, Unger‐Manhart, Nicole, Nakowitsch, Sabine, Goessl, Andreas, Savli, Markus, Zieglmayer, René, Prieschl‐Grassauer, Eva

“…Background Budesonide, a poorly water‐soluble corticosteroid, is currently marketed as a suspension. Budesolv is a novel aqueous formulation containing…”
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Regional differences in SERT occupancy after acute and prolonged SSRI intake investigated by brain PET by Baldinger, Pia, Kranz, Georg S., Haeusler, Daniela, Savli, Markus, Spies, Marie, Philippe, Cecile, Hahn, Andreas, Höflich, Anna, Wadsak, Wolfgang, Mitterhauser, Markus, Lanzenberger, Rupert, Kasper, Siegfried

“…Blocking of the serotonin transporter (SERT) represents the initial mechanism of action of selective serotonin reuptake inhibitors (SSRIs) which can be…”
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Decongestant Effect of “Coldamaris Akut”, a Carrageenan- and Sorbitol-Containing Nasal Spray in Seasonal Allergic Rhinitis by Unger-Manhart, Nicole, Morokutti-Kurz, Martina, Zieglmayer, Petra, Russo, Antonella, Siegl, Cornelia, König-Schuster, Marielle, Koller, Christiane, Graf, Philipp, Graf, Christine, Lemell, Patrick, Savli, Markus, Zieglmayer, René, Dellago, Hanna, Prieschl-Grassauer, Eva

“…This study aimed to develop a hyperosmolar, barrier-forming nasal spray based on carrageenan and sorbitol, and to demonstrate its decongestant effect in the…”
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The norepinephrine transporter in attention-deficit/hyperactivity disorder investigated with positron emission tomography by Vanicek, Thomas, Spies, Marie, Rami-Mark, Christina, Savli, Markus, Höflich, Anna, Kranz, Georg S, Hahn, Andreas, Kutzelnigg, Alexandra, Traub-Weidinger, Tatjana, Mitterhauser, Markus, Wadsak, Wolfgang, Hacker, Marcus, Volkow, Nora D, Kasper, Siegfried, Lanzenberger, Rupert

“…Attention-deficit/hyperactivity disorder (ADHD) research has long focused on the dopaminergic system's contribution to pathogenesis, although the results have…”
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Alleviation of Allergic Rhinoconjunctivitis Symptoms in Participants Treated with a 0.005% Tacrolimus Eye-Drop Solution by Sladek, Svenja, Unger-Manhart, Nicole, Siegl, Cornelia, Dellago, Hanna, Zieglmayer, Petra U, Lemell, Patrick, Savli, Markus, Zieglmayer, René, Geitzenauer, Wolfgang, Längauer, Matthias, Prieschl-Grassauer, Eva

“…This randomized, placebo-controlled, crossover, double-blind trial aimed to evaluate the efficacy and safety of Tacrosolv, a novel 0.005% tacrolimus eye-drop…”
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Neuropsychiatric deep brain stimulation for translational neuroimaging by Höflich, Anna, Savli, Markus, Comasco, Erika, Moser, Ulrike, Novak, Klaus, Kasper, Siegfried, Lanzenberger, Rupert

“…From a neuroimaging point of view, deep brain stimulation (DBS) in psychiatric disorders represents a unique source of information to probe results gained in…”
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Imaging treatment effects in depression by Höflich, Anna, Baldinger, Pia, Savli, Markus, Lanzenberger, Rupert, Kasper, Siegfried

“…In the past years a multitude of studies has revealed alterations on a neuromolecular, structural and network level in patients with major depressive disorder…”
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Lateralization of the serotonin-1A receptor distribution in language areas revealed by PET by Fink, Martin, Wadsak, Wolfgang, Savli, Markus, Stein, Patrycja, Moser, Ulrike, Hahn, Andreas, Mien, Leonhard-Key, Kletter, Kurt, Mitterhauser, Markus, Kasper, Siegfried, Lanzenberger, Rupert

“…Lateralization is a well described aspect of the human brain. A plethora of morphological, cytological and functional studies describes hemispheric asymmetry…”
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Carrageenan-Containing Nasal Spray Alleviates Allergic Symptoms in Participants with Grass Pollen Allergy: A Randomized, Controlled, Crossover Clinical Trial by Unger-Manhart, Nicole, Morokutti-Kurz, Martina, Zieglmayer, Petra U, Lemell, Patrick, Savli, Markus, Zieglmayer, René, Prieschl-Grassauer, Eva

“…Nonpharmacological, barrier-forming nasal sprays are used to manage symptoms of allergic rhinitis. We aim to evaluate the safety and effectiveness of Callergin…”
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Effects of hormone replacement therapy on cerebral serotonin-1A receptor binding in postmenopausal women examined with [ carbonyl -11 C]WAY-100635 by Kranz, Georg S, Rami-Mark, Christina, Kaufmann, Ulrike, Baldinger, Pia, Hahn, Andreas, Höflich, Anna, Savli, Markus, Stein, Patrycja, Wadsak, Wolfgang, Mitterhauser, Markus, Winkler, Dietmar, Lanzenberger, Rupert, Kasper, Siegfried

“…Summary Preclinical research points to a strong modulatory influence of gonadal hormones on the serotonin system. However, human data corroborating this…”
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