Search Results - "Savla, Ronak"

Review and analysis of FDA approved drugs using lipid-based formulations by Savla, Ronak, Browne, Jeff, Plassat, Vincent, Wasan, Kishor M., Wasan, Ellen K.

“…Lipid-based drug delivery systems (LBDDS) are one of the most studied bioavailability enhancement technologies and are utilized in a number of U.S. Food and…”
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Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells by Xiao, Yan, Gao, Xiugong, Taratula, Oleh, Treado, Stephen, Urbas, Aaron, Holbrook, R David, Cavicchi, Richard E, Avedisian, C Thomas, Mitra, Somenath, Savla, Ronak, Wagner, Paul D, Srivastava, Sudhir, He, Huixin

“…Nanocarrier-based antibody targeting is a promising modality in therapeutic and diagnostic oncology. Single-walled carbon nanotubes (SWNTs) exhibit two unique…”
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Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes by Taratula, Oleh, Garbuzenko, Olga, Savla, Ronak, Wang, Y Andrew, He, Huixin, Minko, Tamara

“…The ability of Superparamagnetic Iron Oxide (SPIO) nanoparticles and Poly(Propyleneimine) generation 5 dendrimers (PPI G5) to cooperatively provoke siRNA…”
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Genotoxicity of different nanocarriers: possible modifications for the delivery of nucleic acids by Shah, Vatsal, Taratula, Oleh, Garbuzenko, Olga B, Patil, Mahesh L, Savla, Ronak, Zhang, Min, Minko, Tamara

“…The prevention of cyto- and genotoxicity of nanocarriers is an important task in nanomedicine. In the present investigation, we, at the first time using…”
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Nanoparticle design considerations for molecular imaging of apoptosis: Diagnostic, prognostic, and therapeutic value by Savla, Ronak, Minko, Tamara

“…The present review analyzes various approaches for the design and synthesis of different nanoparticles for imaging and therapy. Nanoparticles for computed…”
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Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer by Savla, Ronak, Taratula, Oleh, Garbuzenko, Olga, Minko, Tamara

“…In this study, we report the design and delivery of a tumor-targeted, pH-responsive quantum dot-mucin1 aptamer-doxorubicin (QD-MUC1-DOX) conjugate for the…”
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Nanotechnology approaches for inhalation treatment of fibrosis by Savla, Ronak, Minko, Tamara

“…Abstract Cystic fibrosis (CF) is an autosomal recessive monogenetic disease that afflicts nearly 70 000 patients worldwide. The mutation results in the…”
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Tumor-Targeted Responsive Nanoparticle-Based Systems for Magnetic Resonance Imaging and Therapy by Savla, Ronak, Garbuzenko, Olga B., Chen, Suzie, Rodriguez-Rodriguez, Lorna, Minko, Tamara

“…Purpose Design and synthesis of a tumor responsive nanoparticle-based system for imaging and treatment of various cancers. Methods Manganese oxide…”
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Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery by Taratula, Oleh, Garbuzenko, Olga B., Kirkpatrick, Paul, Pandya, Ipsit, Savla, Ronak, Pozharov, Vitaly P., He ⁎, Huixin, Minko, Tamara

“…Low penetration ability of Small Interfering RNA (siRNA) through the cellular plasma membrane combined with its limited stability in blood, limits the…”
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Insights and Lessons from a Scientific Conference on Non-Invasive Delivery of Macromolecules by Savla, Ronak, Mrsny, Randall J., Park, Kinam, Aubert, Isabelle, Stamoran, Cornell

“…A growing share of the pharmaceutical development pipeline is occupied by macromolecule drugs, which are primarily administered by injection. Despite decades…”
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Abstract 4405: Tumor-targeted nanotherapeutics by Garbuzenko, Olga B., Kuzmov, Andriy, Sapiezynski, Justin E., Taratula, Oleh, Shah, Vatsal, Zhang, Min, Savla, Ronak, John, Shali, Rodriguez-Rodriguez, Lorna, Minko, Tamara

“…Abstract Directing anticancer agents specifically to tumors and/or cancer cells by targeting specific extracellular receptors fulfills the following three most…”
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Tumor responsive targeted multifunctional nanosystems for cancer imaging, chemo- and siRNA therapy by Savla, Ronak

“…Cancer is one of the most insidious diseases. Compromising of over 100 different types and sharing the unifying factors of uncontrolled growth and metastasis,…”
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Tumor responsive targeted multifunctional nanosystems for cancer imaging, chemo- and siRNA therapy by Savla, Ronak

“…Cancer is one of the most insidious diseases. Compromising of over 100 different types and sharing the unifying factors of uncontrolled growth and metastasis,…”
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Bridging the Gap from Molecule to Drug by Tindal, Stephen, Savla, Ronak

“…Molecule development and dosage form selection In small companies, these two phases in product development, though part of a continuum, are hampered by an…”
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Bridging the Gap from Molecule to Drug: Formulation expertise can smooth the transition of a prospective therapy from medicinal chemistry to drug dosage form by Tindal, Stephen, Savla, Ronak

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Oral Delivery of Macromolecular Drugs: Macromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease by Savla, Ronak, Hartwig, Olga, Chin, William Wei Lim, Loretz, Brigitta, Lehr, Claus-Michael

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