Search Results - "Savinska, L. O."

Alterations in expression of S6K1 isoforms in MCF7 cells have a strong impact on the locomotor activity as well as on S6K1 and Akt signaling by Kosach, V. R., Hotsuliak, N. Ya, Zaiets, I. V., Skorokhod, O. M., Savinska, L. O., Khoruzhenko, A. I., Filonenko, V. V.

“…Aim. To generate and characterize MCF-7 cell lines with altered expression of p85, p70 and p60 S6K1 isoforms: p85-/p70-/p60-MCF-7 and p85-/p70-/p60+MCF-7…”
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The Р60-S6K1 isoform of ribosomal protein S6 kinase 1 is a product of alternative mRNA translation by Zaiets, I. V., Sivchenko, A. S., Khoruzhenko, A. I., Savinska, L. O., Filonenko, V. V.

“…Ribosomal protein S6 kinase 1 (S6K1) is a well-known downstream effector of mTORC1 (mechanistic target of rapamycin complex 1) participating primarily in the…”
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Generation and characterization of polyclonal antibodies specific to N-terminal extension of p85 isoform of ribosomal protein S6 kinase 1 (p85 S6K1) by Savinska, L. O., Klipa, O. M., Khoruzenko, A. I., Shkarina, K. S., Garifulin, O. M., Filonenko, V. V.

“…Aim. Generation of polyclonal antibodies specific to the ribosomal protein S6 kinase isoform – p85S6K1 and directed to the N-terminal (1–23 aa) extension of…”
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Generation of monoclonal antibodies specific to ribosomal protein S6 kinase 1 by Savinska, L. O., Klipa, O. M., Demchuk, N. O., Ovcharenko, G. V., Malanchuk, O. M., Tykhonkova, I. O., Palchevskyy, S. S., Filonenko, V. V.

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Alterations in S6K1 isoforms expression induce Epithelial to Mesenchymal Transition and Estrogen Receptor 1 Silencing in human breast adenocarcinoma MCF-7 cells by Garifulin, O. M., Zaiets, I. V., Kosach, V. R., Horak, I. R., Khoruzhenko, A. I., Gotsulyak, N. Ya, Savinska, L. O., Kroupskaya, I. V., Martsynyuk, M. Ye, Drobot, L. B., Filonenko, V. V.

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Comparative characterization of S6 kinase α and β isoforms expression in mammalian tissues by Savinska, L. O., Kijamova, R. G., Pogrebnoy, P. V., Ovсharenko, G. V., Gout, I. T., Filonenko, V. V.

“…The expression of ribosomal S6 kinase α and β isoforms has been analyzed in different rat tissues. The levels of kinase expression have been stated to show…”
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Use of yeast two-hybrid system in search of S6K1 and S6K2 binding partners by Zhyvoloup, O. M., Nemazanyy, I. O., Pobigailo, N. V., Panasyuk, G. G., Palchevskyy, S. S., Kuharenko, O. P., Savinska, L. O., Ovcharenko, G. V., Vudmaska, M. I., Gout, I. T., Matsuka, G. Kh, Filonenko, V. V.

“…The kinase of the ribosomal protein S6 (S6K) is involved in the signalling pathways which regulate the cell proliferation, differentiation and growth. The…”
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Immunohistochemical analysis of S6K1 and S6K2 expression in human breast tumors by Savinska, Liliya O, Lyzogubov, Valeriy V, Usenko, Vasyliy S, Ovcharenko, Galina V, Gorbenko, Olena N, Rodnin, Mykola V, Vudmaska, Mariya I, Pogribniy, Petro V, Kyyamova, Ramziya G, Panasyuk, Ganna G, Nemazanyy, Ivan O, Malets, Milan S, Palchevskyy, Sergey S, Gout, Ivan T, Filonenko, Valeriy V

“…To express recombinant S6K2 in baculovirus expression system; to purify large quantities of recombinant S6K2 for biochemical studies; to generate and…”
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