Search Results - "Savinova, OV"

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage by Libby, Richard T, Li, Yan, Savinova, Olga V, Barter, Joseph, Smith, Richard S, Nickells, Robert W, John, Simon W M

“…In glaucoma, harmful intraocular pressure often contributes to retinal ganglion cell death. It is not clear, however, if intraocular pressure directly insults…”
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Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration by Libby, Richard T, Anderson, Michael G, Pang, Iok-Hou, Robinson, Zachary H, Savinova, Olga V, Cosma, I Mihai, Snow, Amy, Wilson, Lawriston A, Smith, Richard S, Clark, Abbot F, John, Simon W M

“…The glaucomas are neurodegenerative diseases involving death of retinal ganglion cells and optic nerve head excavation. A major risk factor for this…”
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Modification of Ocular Defects in Mouse Developmental Glaucoma Models by Tyrosinase by Libby, Richard T., Smith, Richard S., Savinova, Olga V., Zabaleta, Adriana, Martin, Janice E., Gonzalez, Frank J., Simon W. M. John

“…Mutations in the cytochrome P450 family 1, subfamily B, polypeptide 1 (CYP1B1) gene are a common cause of human primary congenital glaucoma (PCG). Here we show…”
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Genetically Increasing Myoc Expression Supports a Necessary Pathologic Role of Abnormal Proteins in Glaucoma by Gould, Douglas B., Miceli-Libby, Laura, Savinova, Olga V., Torrado, Mario, Tomarev, Stanislav I., Smith, Richard S., John, Simon W. M.

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Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function by Kim, Byong Su, Savinova, Olga V., Reedy, Mark V., Martin, Janice, Lun, Yi, Gan, Lin, Smith, Richard S., Tomarev, Stanislav I., John, Simon W. M., Johnson, Randy L.

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Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice [published erratum appears in Invest Ophthalmol Vis Sci 1998 Aug;39(9):1641] by John, SW, Smith, RS, Savinova, OV, Hawes, NL, Chang, B, Turnbull, D, Davisson, M, Roderick, TH, Heckenlively, JR

“…To characterize ocular abnormalities associated with iris atrophy in DBA/2J mice and to determine whether mice of this strain develop elevated intraocular…”
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Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development by SMITH, R. S, ZABALETA, A, KUME, T, SAVINOVA, O. V, KIDSON, S. H, MARTIN, J. E, NISHIMURA, D. Y, ALWARD, W. L. M, HOGAN, B. L. M, JOHN, S. W. M

“…Anterior segment developmental disorders, including Axenfeld-Rieger anomaly (ARA), variably associate with harmfully elevated intraocular pressure (IOP), which…”
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By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucoma by Mo, Jun-Song, Anderson, Michael G, Gregory, Meredith, Smith, Richard S, Savinova, Olga V, Serreze, David V, Ksander, Bruce R, Streilein, J Wayne, John, Simon W M

“…Pigment dispersion syndrome causes iris pigment release and often progresses to elevated intraocular pressure and pigmentary glaucoma (PG). Because melanin…”
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Lupane triterpenes and derivatives with antiviral activity by Baltina, L A, Flekhter, O B, Nigmatullina, L R, Boreko, E I, Pavlova, N I, Nikolaeva, S N, Savinova, O V, Tolstikov, G A

“…Betulin and betulinic acid have been modified at the C-3 and C-28 positions and the antiviral activity of derivatives has been evaluated in vitro. It was found…”
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Synthesis and Antiviral Activity of Betulonic Acid Amides and Conjugates with Amino Acids by Flekhter, O. B., Boreko, E. I., Nigmatullina, L. R., Tret'yakova, E. V., Pavlova, N. I., Baltina, L. A., Nikolaeva, S. N., Savinova, O. V., Eremin, V. F., Galin, F. Z., Tolstikov, G. A.

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Synthesis and Pharmacological Activity of 20-Keto-29-norlupane Derivatives by Flekhter, O. B., Giniyatullina, G. V., Galin, F. Z., Baschenko, N. Zh, Makara, N. S., Zarudii, F. S., Boreko, E. I., Savinova, O. V., Pavlova, N. I., Starikova, Z. A., Tolstikov, G. A.

“…New 20-oxo- and hydroxyimino-derivatives of betulin that exhibit immunotropic and antiviral activities were synthesized…”
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Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses by Pavlova, N.I., Savinova, O.V., Nikolaeva, S.N., Boreko, E.I., Flekhter, O.B.

“…Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock…”
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Synthesis and Antiviral Activity of Ureides and Carbamates of Betulinic Acid and Its Derivatives by Flekhter, O. B., Boreko, E. I., Nigmatullina, L. R., Tret'yakova, E. V., Pavlova, N. I., Baltina, L. A., Nikolaeva, S. N., Savinova, O. V., Galin, F. Z., Tolstikov, G. A.

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Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15 by Savinova, O V, Matsukawa, N, Smithies, O, John, S W

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