Search Results - "Savinainen, K"

Presence of the IL‐1RA Allele 2 (IL1RN2) is Associated with Enhanced IL‐1β Production In Vitro by Santtila, S, Savinainen, K, Hurme, M

“…The genes of the interleukin‐1 (IL‐1) complex code for three proteins: IL‐1α, IL‐1β and the IL‐1 receptor antagonist (IL‐1RA). Each of these genes is…”
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Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer by SAVINAINEN, K. J, LINJA, M. J, SARAMÄKI, O. R, TAMMELA, T. L. J, CHANG, G. T. G, BRINKMANN, A. O, VISAKORPI, T

“…The long arm of chromosome 8 is one of the most common regions of amplification in cancers of several organs, especially carcinomas of the breast and prostate…”
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Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer by LINJA, Marika J, SAVINAINEN, Kimmo J, SARAMÄKI, Outi R, TAMMELA, Teuvo L. J, VESSELLA, Robert L, VISAKORPI, Tapio

“…The expression level of the androgen receptor (AR) gene in androgen-dependent and -independent prostate cancer was determined by using real-time quantitative…”
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Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes by Lahdenpohja, N, Savinainen, K, Hurme, M

“…Reactive oxygen species (ROS) are used as signaling molecules in T cell activation. One of the main targets of ROS is the transcription factor nuclear…”
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Presence of the IL-1RA allele 2 (IL1RN2) is associated with enhanced IL-1beta production in vitro by Santtila, S, Savinainen, K, Hurme, M

“…The genes of the interleukin-1 (IL-1) complex code for three proteins: IL-1alpha, IL-1beta and the IL-1 receptor antagonist (IL-1RA). Each of these genes is…”
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Presence of the IL-1RA Allele 2 (IL1RN2) is associated with enhanced IL-(1 beta) production in vitro by Santtila, S, Savinainen, K, Hurme, M

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Expression of Androgen Receptor Coregulators in Prostate Cancer by LINJA, Marika J, PORKKA, Kati P, KANG, Zhikang, SAVINAINEN, Kimmo J, JÄNNE, Olli A, TAMMELA, Teuvo L. J, VESSELLA, Robert L, PALVIMO, Jorma J, VISAKORPI, Tapio

“…Purpose: The androgen receptor (AR)-mediated signaling pathway seems to be essentially involved in the development and progression of prostate cancer. In vitro…”
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Pre-exposure to oxidative stress decreases the NF-κB dependent transcription in T lymphocytes by Hume, M., Lahdenpohja, N., Savinainen, K.

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Expression of ERα and ERβ in prostate cancer by Linja, Marika J., Savinainen, Kimmo J., Tammela, Teuvo L.J., Isola, Jorma J., Visakorpi, Tapio

“…BACKGROUND It has been suggested that estrogens and their receptors (ERs) may be involved in the development and progression of prostate cancer. To elucidate…”
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Expression and Gene Copy Number Analysis of ERBB2 Oncogene in Prostate Cancer by Savinainen, Kimmo J., Saramäki, Outi R., Linja, Marika J., Bratt, Ola, Tammela, Teuvo L.J., Isola, Jorma J., Visakorpi, Tapio

“…An anti- ERBB2 antibody, trastuzumab, has been shown to be highly efficient in the treatment of metastatic breast cancers overexpressing the ERBB2 gene. It has…”
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Amplification of the urokinase gene and the sensitivity of prostate cancer cells to urokinase inhibitors by HELENIUS, MERJA A., SAVINAINEN, KIMMO J., BOVA, G. STEVEN, VISAKORPI, TAPIO

“…OBJECTIVES To evaluate the frequency of the urokinase‐type plasminogen activator (uPA) gene amplification and the sensitivity of prostate cancer cells to uPA…”
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Amplification of hypoxia-inducible factor 1alpha gene in prostate cancer by Saramäki, O R, Savinainen, K J, Nupponen, N N, Bratt, O, Visakorpi, T

“…Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates the expression of genes associated with adaptation to reduced oxygen pressure…”
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Amplification of hypoxia-inducible factor 1α gene in prostate cancer by Saramäki, Outi R, Savinainen, Kimmo J, Nupponen, Nina N, Bratt, Ola, Visakorpi, Tapio

“…Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates the expression of genes associated with adaptation to reduced oxygen pressure…”
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