Search Results - "Savelyev, Victor A."
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Synthesis, Pharmacological Evaluation, and Molecular Modeling of Lappaconitine-1,5-Benzodiazepine Hybrids
Published in Molecules (Basel, Switzerland) (22-05-2023)“…Diterpenoid alkaloids, originating from the amination of natural tetracyclic diterpenes, have long interested scientists due to their medicinal uses and…”
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Hybrides of Alkaloid Lappaconitine with Pyrimidine Motif on the Anthranilic Acid Moiety: Design, Synthesis, and Investigation of Antinociceptive Potency
Published in Molecules (Basel, Switzerland) (27-11-2020)“…Convenient and efficient routes to construct hybrid molecules containing diterpene alkaloid lappaconitine and pyrimidine fragments are reported. One route…”
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1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents
Published in Molecules (Basel, Switzerland) (29-05-2020)“…A series of 1,2-, 1,4-disubstituted or 1,2,4-trisubstituted anthraquinone-based compounds was designed, synthesized, characterized and biologically evaluated…”
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An Efficient Access to 3,5‐Disubstituted Isoxazoles with Anthranilate Ester Moiety: Alkaloid Lappaconitine – Aryl Conjugates with an Isoxazole Linker
Published in Asian journal of organic chemistry (01-10-2021)“…Alkynones have gained great attention as useful building blocks in organic synthesis. They have been emerged as key intermediates in the synthesis of various…”
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Aminocarbonylation of 2-(N-substituted) 5-iodobenzoates: synthesis of glyoxylamido-anthranilates, their cytotoxicity and molecular modeling study
Published in Chemical papers (01-06-2024)“…The aminocarbonylation of ethyl 2-substituted 5-iodobenzoate has been investigated in the presence of a series of amine nucleophiles, providing an efficient…”
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Design, synthesis, cytotoxicity, and molecular modeling study of 2,4,6-trisubstituted pyrimidines with anthranilate ester moiety
Published in Medicinal chemistry research (15-04-2019)“…A series of 2,4,6-trisubstituted pyrimidines with antharanilic acid ester moiety have been designed and synthesized by employing a one-pot multicomponent…”
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Synthesis, characterization and anticancer evaluation of nitrogen-substituted 1-(3-aminoprop-1-ynyl)-4-hydroxyanthraquinone derivatives
Published in Medicinal chemistry research (01-08-2021)“…Anthraquinones are of significant interest due to their biological activity, coloring properties, and synthetic applications. Here, we describe a mild and…”
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