Development and Evaluation of a Flocked Nasal Midturbinate Swab for Self-Collection in Respiratory Virus Infection Diagnostic Testing

We developed and evaluated flocked nasal midturbinate swabs obtained from 55 asymptomatic and 108 symptomatic volunteers. Self-collected swabs obtained from asymptomatic volunteers yielded numbers of respiratory epithelial cells comparable to those of staff-collected nasal (n = 55) or nasopharyngeal...

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Bibliographic Details
Published in:	Journal of Clinical Microbiology Vol. 48; no. 9; pp. 3340 - 3342
Main Authors:	Smieja, Marek, Castriciano, Santina, Carruthers, Susan, So, Geoffrey, Chong, Sylvia, Luinstra, Kathy, Mahony, James B, Petrich, Astrid, Chernesky, Max, Savarese, Mario, Triva, Daniele
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-09-2010 American Society for Microbiology (ASM)
Subjects:	Adult Biological and medical sciences Fundamental and applied biological sciences. Psychology Human Experimentation Humans Microbiology Nasal Mucosa - virology Polymerase Chain Reaction - methods Respiratory Tract Infections - diagnosis Respiratory Tract Infections - virology Self Care - methods Sensitivity and Specificity Virology Virology - methods Virus Diseases - diagnosis Virus Diseases - virology Viruses - isolation & purification Infection Respiratory disease Viral disease Samplings
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Summary:	We developed and evaluated flocked nasal midturbinate swabs obtained from 55 asymptomatic and 108 symptomatic volunteers. Self-collected swabs obtained from asymptomatic volunteers yielded numbers of respiratory epithelial cells comparable to those of staff-collected nasal (n = 55) or nasopharyngeal (n = 20) swabs. Specific viruses were detected in swabs self-collected by 42/108 (38.9%) symptomatic volunteers by multiplex PCR.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Undefined-1 ObjectType-Feature-3 content type line 23 ObjectType-Feature-1
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.02235-09