Search Results - "Savage, Philip M."

EMA/CO for High-Risk Gestational Trophoblastic Neoplasia: Good Outcomes With Induction Low-Dose Etoposide-Cisplatin and Genetic Analysis by ALIFRANGIS, Constantine, AGARWAL, Roshan, SHORT, Delia, FISHER, Rosemary A, SEBIRE, Neil J, HARVEY, Richard, SAVAGE, Philip M, SECKL, Michael J

“…Patients with high-risk (International Federation of Gynecology and Obstetrics score ≥ 7) gestational trophoblastic neoplasia (GTN) frequently receive…”
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Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study by Schmid, Peter, Dr, Nagai, Yutaka, MD, Agarwal, Roshan, MRCP, Hancock, Barry, Prof, Savage, Philip M, FRCP, Sebire, Neil J, FRCPath, Lindsay, Iain, FRCPath, Wells, Michael, Prof, Fisher, Rosemary A, PhD, Short, Delia, Newlands, Edward S, Prof, Wischnewsky, Manfred B, Prof, Seckl, Michael J, Prof

“…Summary Background Placental-site trophoblastic tumours are a rare form of gestational trophoblastic disease and consequently information about optimum…”
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Chemotherapy and human chorionic gonadotropin concentrations 6 months after uterine evacuation of molar pregnancy: a retrospective cohort study by Agarwal, Roshan, MRCP, Teoh, Suliana, MRCP, Short, Delia, BSc, Harvey, Richard, PhD, Savage, Philip M, FRCP, Seckl, Michael J, Prof

“…Summary Background Indications for chemotherapy in gestational trophoblastic disease include raised human chorionic gonadotropin (hCG) concentrations 6 months…”
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Malignant Ovarian Germ Cell Tumors: Identification of Novel Prognostic Markers and Long-Term Outcome After Multimodality Treatment by MURUGAESU, Nirupa, SCHMID, Peter, DANCEY, Gairin, AGARWAL, Roshan, HOLDEN, Lydia, MCNEISH, Lain, SAVAGE, Philip M, NEWLANDS, Edward S, RUSTIN, Gordon J. S, SECKL, Michael J

“…Malignant ovarian germ cell tumors are rare and knowledge about prognostic parameters currently is limited. This study was undertaken to evaluate long-term…”
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Chemical Transformations in Proto-Cytoplasmic Media. Phosphorus Coupling in the Silica Hydrogel Phase by Gorrell, Ian B, Henderson, Timothy W, Albdeery, Kamal, Savage, Philip M, Kee, Terence P

“…It has been proposed that prebiotic chemical studies on the emergence of primitive life would be most relevant when performed in a hydrogel, rather than an…”
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Successful treatment of metastatic hepatic epithelioid hemangioendothelioma with thalidomide: a case report by Raphael, Claire, Hudson, Emma, Williams, Leslie, Lester, Jason F, Savage, Philip M

“…Hepatic epithelioid hemangioendothelioma is a rare malignancy arising from the vascular endothelial cells within the liver. Historically, the disease is…”
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What is the optimal duration of human chorionic gonadotrophin surveillance following evacuation of a molar pregnancy? A retrospective analysis on over 20,000 consecutive patients by Coyle, Christopher, Short, Dee, Jackson, Lauren, Sebire, Neil J., Kaur, Baljeet, Harvey, Richard, Savage, Philip M., Seckl, Michael J.

“…To quantify the risk of developing post-molar gestational trophoblastic neoplasia (pGTN) beyond the first normal human chorionic gonadotrophin (hCG) in women…”
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Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? an international multicenter analysis by Bergamini, Alice, Sarwar, Naveed, Ferrandina, Gabriella, Scarfone, Giovanna, Short, Dee, Aguiar, Xianne, Camnasio, Cristina, Kaur, Baljeet, Savage, Philip M., Cormio, Gennaro, Lim, Adrian, Pignata, Sandro, Mangili, Giorgia, Seckl, Michael J.

“…The role of surveillance after surgery for stage IA-C grade 2 (G2) or grade 3 (G3) immature teratomas (ITs) is controversial with many guidelines advocating…”
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Atypical Placental Site Nodule (APSN) and Association With Malignant Gestational Trophoblastic Disease; A Clinicopathologic Study of 21 Cases by Kaur, Baljeet, Short, Dee, Fisher, Rosemary A, Savage, Philip M, Seckl, Michael J, Sebire, Neil J

“…The WHO Classification of Gestational Trophoblastic Tumors classifies placental site nodule (PSN) as a benign tumor-like trophoblastic neoplasm. Cases of PSN…”
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Response to letter entitled: Re: Can we replace adjuvant chemotherapy with surveillance for stage IA-C immature ovarian teratomas of any grade? An international multicenter analysis by Bergamini, Alice, Sarwar, Naveed, Ferrandina, Gabriella, Scarfone, Giovanna, Short, Dee, Aguiar, Xianne, Camnasio, Cristina, Kaur, Baljeet, Savage, Philip M., Cormio, Gennaro, Lim, Adrian, Pignata, Sandro, Mangili, Giorgia, Seckl, Michael J.

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Mutations in NLRP7 and KHDC3L Confer a Complete Hydatidiform Mole Phenotype on Digynic Triploid Conceptions by Fallahian, Masoumeh, Sebire, Neil J., Savage, Philip M., Seckl, Michael J., Fisher, Rosemary A.

“…ABSTRACT Digynic triploidy is classically associated with a severely growth restricted fetus and a small nonmolar placenta. However, in genotyping hydatidiform…”
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Survival of Women with Gestational Trophoblastic Neoplasia and Liver Metastases: Is It Improving? by AHAMED, Eliyaz, SHORT, Dee, NORTH, Bernard, SAVAGE, Philip M, SECKL, Michael J

“…To determine whether survival outcomes of women with liver metastases from gestational trophoblastic neoplasia (GTN) have improved from the previous finding of…”
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Mutations in NLRP7 are associated with diploid biparental hydatidiform moles, but not androgenetic complete moles by Dixon, Peter H, Trongwongsa, Pirada, Abu-Hayyah, Shadi, Ng, Sze Hwei, Akbar, Syed Ali, Khawaja, Nuzhat P, Seckl, Michael J, Savage, Philip M, Fisher, Rosemary A

“…NLRP7 (NALP7) has been identified as the major gene involved in the inherited predisposition to recurrent molar pregnancies, a rare recessive condition in…”
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Effect of early pregnancy following chemotherapy on disease relapse and fetal outcome in women treated for gestational trophoblastic neoplasia by Williams, Jennet, Short, Dee, Dayal, Linda, Strickland, Sarah, Harvey, Richard, Tin, Terry, Savage, Philip M, Seckl, Michael J

“…To examine the effects of early pregnancy (< 12 months following chemotherapy) on a recent cohort of women treated with modern therapies for gestational…”
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Anti-Müllerian Hormone in Patients Treated with Chemotherapy for Gestational Trophoblastic Neoplasia Does Not Predict Short-Term Fertility by Ghorani, Ehsan, Ramaswami, Ramya, Smith, Richard J, Savage, Philip M, Seckl, Michael J

“…Serum anti-Müllerian hormone (AMH) is an emerging indicator of ovarian reserve which may be predictive of reproductive capacity. Although AMH levels decline…”
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The impact of molecular genetic diagnosis on the management of women with hCG-producing malignancies by Fisher, Rosemary A, Savage, Philip M, MacDermott, Caitriona, Hook, Jane, Sebire, Neil J, Lindsay, Iain, Seckl, Michael J

“…Abstract Objectives. The diagnosis of a gestational trophoblastic tumour (GTT) should be considered in all women presenting with a malignancy and an elevated…”
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Power Doppler Quantification in Assessing Gestational Trophoblastic Neoplasia by Li, Yuanwei, Tang, Meng Xing, Agarwal, Roshan, Patel, Daksha, Eckersley, Robert J, Barrois, Guillaume, Roddie, Mary E, Dayal, Linda, Savage, Philip M, Seckl, Michael J, Lim, Adrian

“…The FIGO score cannot accurately stratify low-risk gestational trophoblastic neoplasia (GTN) patients who develop chemoresistance to single agent methotrexate…”
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Mutations in NLRP 7 and KHDC 3 L Confer a Complete Hydatidiform Mole Phenotype on Digynic Triploid Conceptions by Fallahian, Masoumeh, Sebire, Neil J., Savage, Philip M., Seckl, Michael J., Fisher, Rosemary A.

“…Digynic triploidy is classically associated with a severely growth restricted fetus and a small nonmolar placenta. However, in genotyping hydatidiform moles as…”
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Management and survival of patients with FIGO high-risk gestational trophoblastic neoplasia: the U.K. experience, 1995-2010 by Agarwal, Roshan, Alifrangis, Costi, Everard, Janet, Savage, Philip M, Short, Dee, Tidy, John, Fisher, Rosemary A, Sebire, Neil J, Harvey, Richard, Hancock, Barry W, Coleman, Robert E, Seckl, Michael J

“…To present survival rates of high-risk gestational trophoblastic neoplasia (GTN) (FIGO score > 7) patients treated between 1995 and 2010 in the U.K. Death due…”
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Antibody–peptide–MHC fusion conjugates target non-cognate T cells to kill tumour cells by King, Ben C., Hamblin, Angela D., Savage, Philip M., Douglas, Leon R., Hansen, Ted H., French, Ruth R., Johnson, Peter W. M., Glennie, Martin J.

“…Attempts to generate robust anti-tumour cytotoxic T lymphocyte (CTL) responses using immunotherapy are frequently thwarted by exhaustion and anergy of CTL…”
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