Search Results - "Savage, M P"

Treatment outcomes for 618 women with gestational trophoblastic tumours following a molar pregnancy at the Charing Cross Hospital, 2000–2009 by Sita-Lumsden, A, Short, D, Lindsay, I, Sebire, N J, Adjogatse, D, Seckl, M J, Savage, P M

“…Background: Post-molar pregnancy gestational trophoblastic tumours (GTT) have been curable with chemotherapy treatment for over 50 years. Because of the rarity…”
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Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region by Wang, C M, Dixon, P H, Decordova, S, Hodges, M D, Sebire, N J, Ozalp, S, Fallahian, M, Sensi, A, Ashrafi, F, Repiska, V, Zhao, J, Xiang, Y, Savage, P M, Seckl, M J, Fisher, R A

“…NLRP7 (NALP7) has recently been identified as the causative gene for familial recurrent hydatidiform mole (FRHM), a rare autosomal recessive condition in which…”
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Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel/cisplatin alternating with paclitaxel/etoposide (TP/TE) by Wang, J., Short, D., Sebire, N.J., Lindsay, I., Newlands, E.S., Schmid, P., Savage, P.M., Seckl, M.J.

“…To evaluate the efficacy and toxicity of paclitaxel and cisplatin alternating with paclitaxel and etoposide doublet regimen (TP/TE), for salvage of patients…”
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Early prediction of treatment resistance in low-risk gestational trophoblastic neoplasia using population kinetic modelling of hCG measurements by You, B, Harvey, R, Henin, E, Mitchell, H, Golfier, F, Savage, P M, Tod, M, Wilbaux, M, Freyer, G, Seckl, M J

“…Background: In low-risk gestational trophoblastic neoplasia (GTN) patients, a predictive marker for early identification of methotrexate (MTX) resistance would…”
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Uterine artery pulsatility index: a predictor of methotrexate resistance in gestational trophoblastic neoplasia by Agarwal, R, Harding, V, Short, D, Fisher, R A, Sebire, N J, Harvey, R, Patel, D, Savage, P M, Lim, A K P, Seckl, M J

“…Background: Neo-angiogenesis is a hallmark of cancer. The aim of this study was to test the hypothesis, in a prospective patient cohort, that in low-risk…”
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The relationship of maternal age to molar pregnancy incidence, risks for chemotherapy and subsequent pregnancy outcome by Savage, P. M., Sita-Lumsden, A., Dickson, S., Iyer, R., Everard, J., Coleman, R., Fisher, R. A., Short, D., Casalboni, S., Catalano, K., Seckl, M. J.

“…The national registration and treatment service for molar pregnancies in the UK allows for the collection of accurate data on this relatively rare diagnosis…”
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Late spontaneous resolution of persistent molar pregnancy by Taylor, F, Short, D, Harvey, R, Winter, MC, Tidy, J, Hancock, BW, Savage, PM, Sarwar, N, Seckl, MJ, Coleman, RE

“…Objective To determine the outcome of women with persistently raised but falling human chorionic gonadotrophin (hCG) levels 6 months after surgical evacuation…”
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Histopathological features of biparental complete hydatidiform moles in women with NLRP7 mutations by Sebire, N.J, Savage, P.M, Seckl, M.J, Fisher, R.A

“…Abstract Objectives Molar pregnancies, characterized by hydropic change and trophoblast hyperplasia of chorionic villi, are usually sporadic. Second and third…”
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A comparison of patients with relapsed and chemo-refractory gestational trophoblastic neoplasia by POWLES, T, SAVAGE, P. M, STEBBING, J, SHORT, D, YOUNG, A, BOWER, M, PAPPIN, C, SCHMID, P, SECKL, M. J

“…The majority of women requiring chemotherapy for gestational trophoblastic disease (GTN) are cured with their initial chemotherapy treatment. However, a small…”
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A case of pregnancy following a modified Strassman procedure applied to treat a placental site trophoblastic tumour by Saso, S, Chatterjee, J, Yazbek, J, Thum, Y, Keefe, KW, Abdallah, Y, Naji, O, Lindsay, I, Savage, PM, Seckl, MJ, Smith, JR

“…Please cite this paper as: Saso S, Chatterjee J, Yazbek J, Thum Y, Keefe K, Abdallah Y, Naji O, Lindsay I, Savage P, Seckl M, Smith J. A case of pregnancy…”
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The significance of the time interval between antecedent pregnancy and diagnosis of high-risk gestational trophoblastic tumours by POWLES, T, YOUNG, A, SAMMIT, A, STEBBING, J, SHORT, D, BOWER, M, SAVAGE, P. M, SECKL, M. J, SCHMID, P

“…It is thought that the time interval between the antecedent pregnancy and diagnosis of gestational trophoblastic tumours (GTTs) may influence the outcome of…”
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Risk of recurrent molar pregnancies following complete and partial hydatidiform moles by Eagles, N., Sebire, N.J., Short, D., Savage, P.M., Seckl, M.J., Fisher, R.A.

“…STUDY QUESTION What is the risk of further molar pregnancies for women with one or more hydatidiform moles (HM) in relation to molar subtype. SUMMARY ANSWER…”
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The results of treatment with high-dose chemotherapy and peripheral blood stem cell support for gestational trophoblastic neoplasia by Frijstein, M.M., Lok, C.A.R., Short, D., Singh, K., Fisher, R.A., Hancock, B.W., Tidy, J.A., Sarwar, N., Kanfer, E., Winter, M.C., Savage, P.M., Seckl, M.J.

“…The objective of the study was to evaluate the effect of high-dose chemotherapy (HDC) with peripheral blood stem cell support (PBSCS) on survival of patients…”
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The management and outcome of women with post-hydatidiform mole 'low-risk' gestational trophoblastic neoplasia, but hCG levels in excess of 100 000 IU l by McGrath, S, Short, D, Harvey, R, Schmid, P, Savage, P M, Seckl, M J

“…Gestational trophoblastic neoplasia (GTN) after a hydatidiform mole is either treated with single- or multi-agent chemotherapy determined by a multifactorial…”
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FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development by Fallon, John F., López, Alric, Ros, Maria A., Savage, Mary P., Olwin, Bradley B., Simandl, B. Kay

“…The apical ectodermal ridge permits growth and elongation of amniote limb buds; removal causes rapid changes in mesodermal gene expression, patterned cell…”
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Risk of recurrent molar pregnancies following complete and partial hydatidiform moles by Eagles, N., Sebire, N.J., Short, D., Savage, P.M., Seckl, M.J., Fisher, R.A.

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A retrospective study to evaluate single agent methotrexate treatment in low risk gestational choriocarcinoma in the United Kingdom by Taylor, F, Short, D, Winter, M.C, Tidy, J, Savage, P.M, Sarwar, N, Hancock, B.W, Seckl, M.J, Coleman, R.E

“…Abstract Objective To determine whether single agent chemotherapy with intramuscular methotrexate 50 mg administered on days 1, 3, 5, and 7 and oral folinic…”
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Relapse rates after two versus three consolidation courses of methotrexate in the treatment of low-risk gestational trophoblastic neoplasia by Lybol, C, Sweep, F.C.G.J, Harvey, R, Mitchell, H, Short, D, Thomas, C.M.G, Ottevanger, P.B, Savage, P.M, Massuger, L.F.A.G, Seckl, M.J

“…Abstract Objective Methotrexate (MTX) alternating with folinic acid is a commonly used treatment regimen for low-risk gestational trophoblastic neoplasia…”
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Fate of lesion-related side branches after coronary artery stenting by Fischman, David L., Savage, Michael P., Leon, Martin B., Schatz, Richard A., Ellis, Stephen, Cleman, Michael W., Hirshfeld, John W., Teirstein, Paul, Bailey, Steven, Walker, Craig M., Goldberg, Sheldon

“…Objectives. The aim of this study was to assess the immediate and long-term patency of lesion-associated side branches after coronary artery stenting…”
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Distribution of FGF‐2 suggests it has a role in chick limb bud growth by Savage, Mary Pfann, Fallon, John F., Hart, Charles E., Riley, Bruce B., Sasse, Joachim, Olwin, Bradley B.

“…We developed and characterized antibodies specific for FGF‐2 and used them to locate FGF‐2 during chick embryo development. A series of micrographs…”
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