Search Results - "Sautiere, Pierre"
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Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection
Published in Journal of nanobiotechnology (04-12-2019)“…The functional preservation of the central nervous system (CNS) is based on the neuronal plasticity and survival. In this context, the neuroinflammatory state…”
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Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium‐binding adapter molecule 1 (Iba1/alias aif‐1)
Published in Developmental neurobiology (Hoboken, N.J.) (01-10-2014)“…ABSTRACT The Ionized calcium‐Binding Adapter molecule 1 (Iba1), also known as Allograft Inflammatory Factor 1 (AIF‐1), is a 17 kDa cytokine‐inducible protein,…”
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Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes
Published in Toxins (10-11-2022)“…The pharmacology of calcium-activated chloride current is not well developed. Peptides from scorpion venom present potent pharmacological actions on ionic…”
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Innate Immune Responses of a Scleractinian Coral to Vibriosis
Published in The Journal of biological chemistry (24-06-2011)“…Scleractinian corals are the most basal eumetazoan taxon and provide the biological and physical framework for coral reefs, which are among the most diverse of…”
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Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons
Published in International journal of molecular sciences (19-12-2018)“…In healthy or pathological brains, the neuroinflammatory state is supported by a strong communication involving microglia and neurons. Recent studies indicate…”
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ALK4/5-dependent TGF-β signaling contributes to the crosstalk between neurons and microglia following axonal lesion
Published in Scientific reports (03-05-2019)“…Neuronal activity is closely influenced by glia, especially microglia which are the resident immune cells in the central nervous system (CNS). Microglia in…”
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A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis
Published in Glia (01-11-2010)“…In contrast to mammals, the medicinal leech Hirudo medicinalis can completely repair its central nervous system (CNS) after injury. This invertebrate model…”
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The Leech Nervous System: A Valuable Model to Study the Microglia Involvement in Regenerative Processes
Published in Clinical & developmental immunology (01-01-2013)“…Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia…”
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Hedistin: A novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor
Published in Developmental and comparative immunology (2007)“…A novel antimicrobial peptide, named hedistin was identified from the coelomocytes of Nereis diversicolor. Hedistin shows no obvious similarities with other…”
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Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis
Published in Journal of neuroinflammation (22-02-2012)“…In invertebrates, the medicinal leech is considered to be an interesting and appropriate model to study neuroimmune mechanisms. Indeed, this non-vertebrate…”
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Molecular Characterization of Two Novel Antibacterial Peptides Inducible upon Bacterial Challenge in an Annelid, the Leech Theromyzon tessulatum
Published in The Journal of biological chemistry (23-07-2004)“…Two novel antimicrobial peptides named theromacin and theromyzin were isolated and characterized from the coelomic liquid of the leech Theromyzon tessulatum …”
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Halocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa
Published in Journal of peptide science (01-01-2009)“…We report here the screening of five marine invertebrate species from two taxa (tunicates and echinoderms) for the presence of cationic antimicrobial peptides…”
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Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis following a CNS injury
Published in Medical science monitor (19-04-2014)“…The medicinal leech is considered as a complementary and appropriate model to study immune functions in the central nervous system (CNS). In a context in which…”
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Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord
Published in Molecular immunology (01-02-2009)“…In vertebrates, central nervous system (CNS) protection is dependent on many immune cells including microglial cells. Indeed, activated microglial cells are…”
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Proteomics Demonstration That Normal Breast Epithelial Cells Can Induce Apoptosis of Breast Cancer Cells through Insulin-like Growth Factor-binding Protein-3 and Maspin
Published in Molecular & cellular proteomics (01-07-2007)“…Normal breast epithelial cells are known to exert an apoptotic effect on breast cancer cells, resulting in a potential paracrine inhibition of breast tumor…”
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Up-regulation of Neurohemerythrin Expression in the Central Nervous System of the Medicinal Leech, Hirudo medicinalis, following Septic Injury
Published in The Journal of biological chemistry (15-10-2004)“…We report here some results of a proteomic analysis of changes in protein expression in the leech Hirudo medicinalis in response to septic injury. Comparison…”
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Isolation and Characterization of a New Peroxiredoxin from Poplar Sieve Tubes That Uses Either Glutaredoxin or Thioredoxin as a Proton Donor
Published in Plant physiology (Bethesda) (01-11-2001)“…A sequence coding for a peroxiredoxin (Prx) was isolated from a xylem/phloem cDNA library from Populus trichocarpa and subsequently inserted into an expression…”
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Chromatin condensation, cysteine-rich protamine, and establishment of disulphide interprotamine bonds during spermiogenesis of Eledone cirrhosa (Cephalopoda)
Published in European journal of cell biology (01-06-2002)“…During spermiogenesis in Eledone cirrhosa a single protamine substitutes for histones in nuclei of developing spermatids. This protein displays a peculiar…”
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Isolation and characterization of an extended thioredoxin h from poplar
Published in Physiologia plantarum (01-02-2002)“…A cDNA coding for a thioredoxin h has been isolated from a xylem/phloem poplar cDNA library by RACE‐PCR. The nucleotide sequence called popTrx‐h2 is homologous…”
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Chromatin organization during spermiogenesis in Octopus vulgaris. II: DNA-interacting proteins
Published in Molecular reproduction and development (01-06-2004)“…In this article we study the proteins responsible for chromatin condensation during spermiogenesis in the cephalopod Octopus vulgaris. The DNA of ripe sperm…”
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