Search Results - "Sause, William E"
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The Suf Iron-Sulfur Cluster Biosynthetic System Is Essential in Staphylococcus aureus, and Decreased Suf Function Results in Global Metabolic Defects and Reduced Survival in Human Neutrophils
Published in Infection and immunity (01-06-2017)“…remains a causative agent for morbidity and mortality worldwide. This is in part a result of antimicrobial resistance, highlighting the need to uncover novel…”
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Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus
Published in Journal of bacteriology (15-04-2018)“…subverts innate defenses during infection in part by killing host immune cells to exacerbate disease. This human pathogen intercepts host cues and activates a…”
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The Helicobacter pylori Autotransporter ImaA (HP0289) Modulates the Immune Response and Contributes to Host Colonization
Published in Infection and Immunity (01-07-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Recombination-Based In Vivo Expression Technology Identifies Helicobacter pylori Genes Important for Host Colonization
Published in Infection and Immunity (01-12-2008)“…Here we undertook to identify colonization and gastric disease-promoting factors of the human gastric pathogen Helicobacter pylori as genes that were induced…”
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The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus
Published in Proceedings of the National Academy of Sciences - PNAS (02-07-2019)“…The pathogen Staphylococcus aureus colonizes and infects a variety of different sites within the human body. To adapt to these different environments, S…”
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Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections
Published in Trends in pharmacological sciences (Regular ed.) (01-03-2016)“…The growing incidence of serious infections mediated by methicillin-resistant Staphylococcus aureus (MRSA) strains poses a significant risk to public health…”
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Conserved transcriptional unit organization of the cag pathogenicity island among Helicobacter pylori strains
Published in Frontiers in cellular and infection microbiology (2012)“…The Helicobacter pyloricag pathogenicity island (cag PAI) encodes a type IV secretion system that is more commonly found in strains isolated from patients with…”
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Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus
Published in Proceedings of the National Academy of Sciences - PNAS (29-01-2019)“…The past two decades have witnessed an alarming expansion of staphylococcal disease caused by community-acquired methicillin-resistant (CA-MRSA). The factors…”
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Genome Plasticity of agr -Defective Staphylococcus aureus during Clinical Infection
Published in Infection and immunity (01-10-2018)“…Therapy for bacteremia caused by is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such…”
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Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence
Published in mBio (23-01-2018)“…is a versatile bacterial pathogen that can cause significant disease burden and mortality. Like other pathogens, must adapt to its environment to produce…”
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The Helicobacter pylori Autotransporter ImaA Tempers the Bacterium's Interaction with α5β1 Integrin
Published in Infection and immunity (2017)“…The human pathogen Helicobacter pylori uses the host receptor α β integrin to trigger inflammation in host cells via its cag pathogenicity island (cag PAI)…”
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The Helicobacter pylori Autotransporter ImaA Tempers the Bacterium's Interaction with α 5 β 1 Integrin
Published in Infection and immunity (01-01-2017)“…ABSTRACT The human pathogen Helicobacter pylori uses the host receptor α 5 β 1 integrin to trigger inflammation in host cells via its cag pathogenicity island…”
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Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus
Published in Science translational medicine (16-01-2019)“…A key aspect underlying the severity of infections caused by is the abundance of virulence factors that the pathogen uses to thwart critical components of the…”
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Three SpoA-domain proteins interact in the creation of the flagellar type III secretion system in Helicobacter pylori
Published in The Journal of biological chemistry (07-09-2018)“…Bacterial flagella are rotary nanomachines that contribute to bacterial fitness in many settings, including host colonization. The flagellar motor relies on…”
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SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus
Published in mBio (14-08-2024)“…Severe COVID-19 has been associated with coinfections with bacterial and fungal pathogens. Notably, patients with COVID-19 who develop bacteremia exhibit…”
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Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis
Published in Journal of bacteriology (15-12-2017)“…is a major human pathogen that imposes a great burden on the health care system. In the development of antistaphylococcal modalities intended to reduce the…”
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Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection
Published in mBio (13-03-2018)“…is a Gram-positive opportunistic pathogen that causes superficial and invasive infections in the hospital and community. High mortality from infection…”
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Recombination-Based In Vivo Expression Technology Identifies Helicobacter pylori Genes Important for Host Colonization
Published in Infection and immunity (01-11-2010)Get full text
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Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillinresistant Staphylococcus aureus
Published in Proceedings of the National Academy of Sciences - PNAS (29-01-2019)“…The past two decades have witnessed an alarming expansion of staphylococcal disease caused by community-acquired methicillinresistant Staphylococcus aureus…”
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italic toggle="yes">Staphylococcus aureus /italic> Responds to the Central Metabolite Pyruvate To Regulate Virulence
Published in mBio (01-03-2018)“…ABSTRACT Staphylococcus aureus is a versatile bacterial pathogen that can cause significant disease burden and mortality. Like other pathogens, S. aureus must…”
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