Search Results - "Sausbier, Matthias"

Role of KCNMA1 in breast cancer by Oeggerli, Martin, Tian, Yuemin, Ruiz, Christian, Wijker, Barbara, Sauter, Guido, Obermann, Ellen, Güth, Uwe, Zlobec, Inti, Sausbier, Matthias, Kunzelmann, Karl, Bubendorf, Lukas

“…KCNMA1 encodes the α-subunit of the large conductance, voltage and Ca(2+)-activated (BK) potassium channel and has been reported as a target gene of genomic…”
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Dual role of protein kinase C on BK channel regulation by Zhou, Xiao-Bo, Wulfsen, Iris, Utku, Emine, Sausbier, Ulrike, Sausbier, Matthias, Wieland, Thomas, Ruth, Peter, Korth, Michael

“…Large conductance voltage- and Ca²⁺-activated potassium channels (BK channels) are important feedback regulators in excitable cells and are potently regulated…”
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Cyclic GMP-Dependent Regulation of Vascular Tone and Blood Pressure Involves Cysteine-Rich LIM-Only Protein 4 (CRP4) by Längst, Natalie, Adler, Julia, Schweigert, Olga, Kleusberg, Felicia, Cruz Santos, Melanie, Knauer, Amelie, Sausbier, Matthias, Zeller, Tanja, Ruth, Peter, Lukowski, Robert

“…The cysteine-rich LIM-only protein 4 (CRP4), a LIM-domain and zinc finger containing adapter protein, has been implicated as a downstream effector of the…”
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Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels by Chen, Xiaowei, Kovalchuk, Yury, Adelsberger, Helmuth, Henning, Horst A., Sausbier, Matthias, Wietzorrek, Georg, Ruth, Peter, Yarom, Yosef, Konnerth, Arthur, Llinas, Rodolfo R.

“…The large-conductance voltage- and calcium-activated potassium (BK) channels are ubiquitously expressed in the brain and play an important role in the…”
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Distal colonic K+ secretion occurs via BK channels by SAUSBIER, Matthias, MATOS, Joana E, SAUSBIER, Ulrike, BERANEK, Golo, ARNTZ, Claudia, NEUHUBER, Winfried, RUTH, Peter, LEIPZIGER, Jens

“…K(+) secretion in the kidney and distal colon is a main determinant of K(+) homeostasis. This study investigated the identity of the relevant luminal secretory…”
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Critical role for cochlear hair cell BK channels for coding the temporal structure and dynamic range of auditory information for central auditory processing by Kurt, Simone, Sausbier, Matthias, Rüttiger, Lukas, Brandt, Niels, Moeller, Christoph K., Kindler, Jennifer, Sausbier, Ulrike, Zimmermann, Ulrike, Straaten, Harald, Neuhuber, Winfried, Engel, Jutta, Knipper, Marlies, Ruth, Peter, Schulze, Holger

“…Large conductance, voltage‐ and Ca2+‐activated K+ (BK) channels in inner hair cells (IHCs) of the cochlea are essential for hearing. However, germ‐line…”
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BK channels control cerebellar Purkinje and Golgi cell rhythmicity in vivo by Cheron, Guy, Sausbier, Matthias, Sausbier, Ulrike, Neuhuber, Winfried, Ruth, Peter, Dan, Bernard, Servais, Laurent

“…Calcium signaling plays a central role in normal CNS functioning and dysfunction. As cerebellar Purkinje cells express the major regulatory elements of calcium…”
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Neuronal Ca2+-activated K+ channels limit brain infarction and promote survival by Liao, Yiliu, Kristiansen, Ase-Marit, Oksvold, Cecilie P, Tuvnes, Frode A, Gu, Ning, Rundén-Pran, Elise, Ruth, Peter, Sausbier, Matthias, Storm, Johan F

“…Neuronal calcium-activated potassium channels of the BK type are activated by membrane depolarization and intracellular Ca(2+) ions. It has been suggested that…”
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Cysteine-Rich Protein 2, a Novel Downstream Effector of cGMP/cGMP-Dependent Protein Kinase I-Mediated Persistent Inflammatory Pain by Schmidtko, Achim, Gao, Wei, Sausbier, Matthias, Rauhmeier, Inga, Sausbier, Ulrike, Niederberger, Ellen, Scholich, Klaus, Huber, Andrea, Neuhuber, Winfried, Allescher, Hans-Dieter, Hofmann, Franz, Tegeder, Irmgard, Ruth, Peter, Geisslinger, Gerd

“…The cGMP/cGMP-dependent protein kinase I (cGKI) signaling pathway plays an important role in spinal nociceptive processing. However, downstream targets of cGKI…”
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Osteopenia due to enhanced cathepsin K release by BK channel ablation in osteoclasts by Sausbier, Ulrike, Dullin, Christian, Missbach-Guentner, Jeannine, Kabagema, Clement, Flockerzie, Katarina, Kuscher, Gerd Marten, Stuehmer, Walter, Neuhuber, Winfried, Ruth, Peter, Alves, Frauke, Sausbier, Matthias

“…The process of bone resorption by osteoclasts is regulated by Cathepsin K, the lysosomal collagenase responsible for the degradation of the organic bone matrix…”
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Reduced Inflammatory Hyperalgesia with Preservation of Acute Thermal Nociception in Mice Lacking cGMP-Dependent Protein Kinase I by Tegeder, Irmgard, Del Turco, Domenico, Schmidtko, Achim, Sausbier, Matthias, Feil, Robert, Hofmann, Franz, Deller, Thomas, Ruth, Peter, Geisslinger, Gerd, Beavo, Joseph A.

“…cGMP-dependent protein kinase I (PKG-I) has been suggested to contribute to the facilitation of nociceptive transmission in the spinal cord presumably by…”
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Hypothalamic-Pituitary-Adrenal Axis Hyporesponsiveness to Restraint Stress in Mice Deficient for Large-Conductance Calcium- and Voltage-Activated Potassium (BK) Channels by Brunton, Paula J, Sausbier, Matthias, Wietzorrek, Georg, Sausbier, Ulrike, Knaus, Hans-Guenther, Russell, John A, Ruth, Peter, Shipston, Michael J

“…Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, releasing ACTH from the anterior pituitary gland and glucocorticoids from the adrenal cortex…”
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Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion by Sørensen, Mads V., Matos, Joana E., Sausbier, Matthias, Sausbier, Ulrike, Ruth, Peter, Praetorius, Helle A., Leipziger, Jens

“…Mammalian K + homeostasis results from highly regulated renal and intestinal absorption and secretion, which balances the unregulated K + intake. Aldosterone…”
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Blunted IgE-Mediated Activation of Mast Cells in Mice Lacking the Ca2+-Activated K+ Channel KCa3.1 by Shumilina, Ekaterina, Lam, Rebecca S, Wolbing, Florian, Matzner, Nicole, Zemtsova, Irina M, Sobiesiak, Malgorzata, Mahmud, Hasan, Sausbier, Ulrike, Biedermann, Tilo, Ruth, Peter, Sausbier, Matthias, Lang, Florian

“…Mast cell stimulation by Ag is followed by the opening of Ca(2+)-activated K(+) channels, which participate in the orchestration of mast cell degranulation…”
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2125 In vivo molecular MRI of carotid artery injury in mice using an elastin-binding contrast agent by Makowski, Marcus R, Sausbier, Ulrike, Liao, Yi Liu, Schwaiger, Markus, Neuhuber, Winfried, Robinson, Simon, Ruth, Peter, Sausbier, Matthias, Botnar, Rene M

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Ca2+ -activated K+ channels of the BK-type in the mouse brain by Sausbier, Ulrike, Sausbier, Matthias, Sailer, Claudia A, Arntz, Claudia, Knaus, Hans-Günther, Neuhuber, Winfried, Ruth, Peter

“…An antibody against the 442 carboxy-terminal amino acids of the BK channel alpha-subunit detects high immunoreactivity within the telencephalon in cerebral…”
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Deletion of the Ca2+-Activated Potassium (BK) α-Subunit but Not the BKβ1-Subunit Leads to Progressive Hearing Loss by Rüttiger, Lukas, Sausbier, Matthias, Zimmermann, Ulrike, Winter, Harald, Braig, Claudia, Engel, Jutta, Knirsch, Martina, Arntz, Claudia, Langer, Patricia, Hirt, Bernhard, Müller, Marcus, Köpschall, Iris, Pfister, Markus, Münkner, Stefan, Rohbock, Karin, Pfaff, Imke, Rüsch, Alfons, Ruth, Peter, Knipper, Marlies, Latorre, Ramon

“…The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of…”
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Control of hypothalamic–pituitary–adrenal stress axis activity by the intermediate conductance calcium‐activated potassium channel, SK4 by Liang, Zhi, Chen, Lie, McClafferty, Heather, Lukowski, Robert, MacGregor, Duncan, King, Jonathan T., Rizzi, Sandra, Sausbier, Matthias, McCobb, David P., Knaus, Hans‐Guenther, Ruth, Peter, Shipston, Michael J.

“…Non‐technical summary  Our ability to respond to stress is critically dependent upon the release of the stress hormone adrenocorticotrophic hormone (ACTH) from…”
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Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice by SAUSBIER, Matthias, AMTZ, Claudia, ABDULLAH, Usamah, KRIPPEIT-DREWS, Peter, FEIL, Robert, HOFMANN, Franz, KNAUS, Hans-Günier, KENYON, Chris, SHIPSTON, Michael J, STORM, Johan F, NEUHUBER, Winfried, KORTH, Michael, BUCURENCIU, Iancu, SCHUBERT, Rudolf, GOLLASCH, Maik, RUTH, Peter, HONG ZHAO, ZHOU, Xiao-Bo, SAUSBIER, Ulrike, FEIL, Susanne, KAMM, Simone, ESSIN, Kyrill, SAILER, Claudia A

“…Abnormally elevated blood pressure is the most prevalent risk factor for cardiovascular disease. The large-conductance, voltage- and Ca2+-dependent K+ (BK)…”
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Adrenaline‐induced colonic K+ secretion is mediated by KCa1.1 (BK) channels by Sørensen, Mads V., Sausbier, Matthias, Ruth, Peter, Seidler, Ursula, Riederer, Brigitte, Praetorius, Helle A., Leipziger, Jens

“…Colonic epithelial K+ secretion is a two‐step transport process with initial K+ uptake over the basolateral membrane followed by K+ channel‐dependent exit into…”
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