Search Results - "Saura Martí, Josep"

Microglial cells in astroglial cultures: a cautionary note by Saura, Josep

“…Primary rodent astroglial-enriched cultures are the most popular model to study astroglial biology in vitro. From the original methods described in the 1970's…”
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Modelling neuroinflammation in vitro: a tool to test the potential neuroprotective effect of anti-inflammatory agents by Gresa-Arribas, Núria, Viéitez, Cristina, Dentesano, Guido, Serratosa, Joan, Saura, Josep, Solà, Carme

“…Neuron-microglia co-cultures treated with pro-inflammatory agents are a useful tool to study neuroinflammation in vitro, where to test the potential…”
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Discovering the 3' UTR-mediated regulation of alpha-synuclein by Marchese, Domenica, Botta-Orfila, Teresa, Cirillo, Davide, Rodriguez, Juan Antonio, Livi, Carmen Maria, Fernández-Santiago, Rubén, Ezquerra, Mario, Martí, Maria J, Bechara, Elias, Tartaglia, Gian Gaetano

“…Recent evidence indicates a link between Parkinson's Disease (PD) and the expression of a-synuclein (SNCA) isoforms with different 3' untranslated regions…”
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Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages by Valente, Tony, Serratosa, Joan, Perpiñá, Unai, Saura, Josep, Solà, Carme

“…In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However,…”
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis by Pulido-Salgado, Marta, Vidal-Taboada, Jose M, Garcia Diaz-Barriga, Gerardo, Serratosa, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals, Josep M, Valledor, Annabel, Solà, Carme, Saura, Josep

“…CCAAT/enhancer binding protein β (C/EBPβ) is a transcription factor that regulates the expression of important pro-inflammatory genes in microglia. Mice…”
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Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β by Straccia, Marco, Gresa-Arribas, Núria, Dentesano, Guido, Ejarque-Ortiz, Aroa, Tusell, Josep M, Serratosa, Joan, Solà, Carme, Saura, Josep

“…Microglia and astrocytes respond to homeostatic disturbances with profound changes of gene expression. This response, known as glial activation or…”
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Parkinsonian Neurotoxins Impair the Pro-inflammatory Response of Glial Cells by Rabaneda-Lombarte, Neus, Xicoy-Espaulella, Efren, Serratosa, Joan, Saura, Josep, Solà, Carme

“…In the case of Parkinson's disease (PD), epidemiological studies have reported that pesticide exposure is a risk factor for its pathology. It has been…”
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Passive experimental autoimmune encephalomyelitis in C57BL/6 with MOG: evidence of involvement of B cells by Mannara, Francesco, Valente, Tony, Saura, Josep, Graus, Francesc, Saiz, Albert, Moreno, Beatriz

“…Experimental autoimmune encephalomyelitis (EAE) is the most relevant animal model to study demyelinating diseases such as multiple sclerosis. EAE can be…”
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis by Pulido Salgado, Marta, Vidal Taboada, José Manuel, Garcia Diaz-Barriga, Gerardo, Serratosa i Serdà, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals i Coll, Josep M, Valledor Fernández, Annabel, Solà i Subirana, Carme, Saura Martí, Josep

“…Background CCAAT/enhancer binding protein β (C/EBPβ) is a transcription factor that regulates the expression of important pro-inflammatory genes in microglia…”
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Inhibition of CD200R1 expression by C/EBP β in reactive microglial cells by Dentesano, Guido, Straccia, Marco, Ejarque-Ortiz, Aroa, Tusell, Josep M, Serratosa, Joan, Saura, Josep, Solà, Carme

“…In physiological conditions, it is postulated that neurons control microglial reactivity through a series of inhibitory mechanisms, involving either cell…”
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