Search Results - "Saunders, N. R."

Efflux transporters in rat placenta and developing brain: transcriptomic and functional response to paracetamol by Koehn, L. M., Huang, Y., Habgood, M. D., Nie, S., Chiou, S. Y., Banati, R. B., Dziegielewska, K. M., Saunders, N. R.

“…Adenosine triphosphate binding cassette (ABC) transporters transfer lipid-soluble molecules across cellular interfaces either directly or after enzymatic…”
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Changes in blood-brain barrier permeability to large and small molecules following traumatic brain injury in mice by Habgood, M. D., Bye, N., Dziegielewska, K. M., Ek, C. J., Lane, M. A., Potter, A., Morganti-Kossmann, C, Saunders, N. R.

“…The entry of therapeutic compounds into the brain and spinal cord is normally restricted by barrier mechanisms in cerebral blood vessels (blood–brain barrier)…”
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Long-term changes in blood-brain barrier permeability and white matter following prolonged systemic inflammation in early development in the rat by Stolp, H. B., Dziegielewska, K. M., Ek, C. J., Potter, A. M., Saunders, N. R.

“…Epidemiological evidence in human fetuses links inflammation during development with white matter damage. Breakdown of the blood–brain barrier has been…”
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Immediate exercise hyperemia in humans is contraction intensity dependent: evidence for rapid vasodilation by Tschakovsky, M. E, Rogers, A. M, Pyke, K. E, Saunders, N. R, Glenn, N, Lee, S. J, Weissgerber, T, Dwyer, E. M

“…School of Physical and Health Education,and Department of Physiology, Human Vascular Control Laboratory, Queen's University, Kingston, Ontario, Canada K7L 3N6…”
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Stimulation of defecation in spinal cord-injured rats by a centrally acting ghrelin receptor agonist by Ferens, D M, Habgood, M D, Saunders, N R, Tan, Y H, Brown, D J, Brock, J A, Furness, J B

“…Study design: Animal proof of principle study. Objectives: To determine whether capromorelin, a compound that causes defecation by stimulating ghrelin…”
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Rapamycin in transplantation: A review of the evidence by Saunders, Richard N., Metcalfe, Mathew S., Nicholson, Michael L.

“…Rapamycin in transplantation: A review of the evidence. The calcineurin inhibitors have been the mainstays of immunosuppression for solid organ transplantation…”
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Breakdown of the blood-brain barrier to proteins in white matter of the developing brain following systemic inflammation by Stolp, H B, Dziegielewska, K M, Ek, C J, Habgood, M D, Lane, M A, Potter, A M, Saunders, N R

“…Compromised blood-brain barrier permeability resulting from systemic inflammation has been implicated as a possible cause of brain damage in fetuses and…”
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Aquaporin-1 in the choroid plexuses of developing mammalian brain by Johansson, P A, Dziegielewska, K M, Ek, C J, Habgood, M D, Møllgård, K, Potter, A, Schuliga, M, Saunders, N R

“…The normal brain develops within a well-controlled stable internal "milieu" protected by specialised mechanisms referred to collectively as blood-brain…”
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Development of the choroid plexus by Dziegielewska, K.M., Ek, J., Habgood, M.D., Saunders, N.R.

“…Mammalian choroid plexuses develop at four sites in the roof of the neural tube shortly after its closure, in the order IVth, lateral, and IIIrd ventricles…”
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BARRIER MECHANISMS IN THE BRAIN, II. IMMATURE BRAIN by Saunders, NR, Habgood, MD, Dziegielewska, KM

“…1. It is widely believed that ‘the’ blood–brain barrier is immature in foetuses and newborns. 2. Much evidence in support of this belief is based on…”
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An algorithm for the management of bile leak following laparoscopic cholecystectomy by Ahmad, F, Saunders, R N, Lloyd, G M, Lloyd, D M, Robertson, G S M

“…The management of bile leaks following laparoscopic cholecystectomy has evolved with increased experience of ERCP and laparoscopy. The purpose of this study…”
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Age-related differences in the local cellular and molecular responses to injury in developing spinal cord of the opossum, Monodelphis domestica by Lane, M. A., Truettner, J. S., Brunschwig, J-P., Gomez, A., Bunge, M. B., Dietrich, W. D., Dziegielewska, K. M., Ek, C. J., VandeBerg, J. L., Saunders, N. R.

“…Immature spinal cord, unlike adult, has an ability to repair itself following injury. Evidence for regeneration, structural repair and development of…”
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Four gland parathyroidectomy without reimplantation in patients with chronic renal failure by Saunders, R N, Karoo, R, Metcalfe, M S, Nicholson, M L

“…Background: The optimal surgical management of patients in end stage chronic renal failure with secondary hyperparathyroidism is controversial. One approach…”
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Significance of R1 resection margin in colon cancer resections in the modern era by Khan, M. A. S., Hakeem, A. R., Scott, N., Saunders, R. N.

“…Aim Circumferential resection margin involvement (R1) in rectal cancer is a predictive factor for poor prognosis. The aim of this study was to confirm the…”
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Expression and localization of P2 nucleotide receptor subtypes during development of the lateral ventricular choroid plexus of the rat by Johansson, P. A., Burnstock, G., Dziegielewska, K. M., Guida, E., McIntyre, P., Saunders, N. R.

“…The choroid plexuses secrete cerebrospinal fluid (CSF) and regulate the brain's internal environment via the blood–CSF barrier. The permeability properties of…”
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Complex chronic conditions among children born to women with schizophrenia by Toufeili, A., Cohen, E., Ray, J.G., Wilton, A.S., Brown, H.K., Saunders, N.R., Dennis, C.L., Holloway, A.C., Morrison, K.M., Hanley, G.E., Oberlander, T.F., Bérard, A., Tu, K., Barker, L.C., Vigod, S.N.

“…Maternal schizophrenia is linked to complications in offspring near the time of birth. Whether there is also a higher future risk of the child having a complex…”
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Breakthrough COVID-19 is mild in vaccinated patients with hematological malignancy receiving tixagevimab-cilgavimab as pre-exposure prophylaxis by Hall, V. G., Lim, C., Saunders, N. R., Klimevski, E., Nguyen, T. H. O., Kedzierski, L., Seymour, J. F., Wadhwa, V., Thursky, K. A., Yong, M. K., Kedzierska, K., Slavin, M. A., Teh, B. W.

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Development of Walking, Swimming and Neuronal Connections after Complete Spinal Cord Transection in the Neonatal Opossum, Monodelphis domestica by Saunders, N. R, Kitchener, P, Knott, G. W, Nicholls, J. G, Potter, A, Smith, T. J

“…Development of coordinated movements was quantitatively assessed in adult opossums (Monodelphis domestica) with thoracic spinal cords transected by (1)…”
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The impact of cyclosporine dose reduction with or without the addition of rapamycin on functional, molecular, and histological markers of chronic allograft nephropathy by Saunders, R N, Bicknell, G R, Nicholson, M L

“…Overexposure to cyclosporine is a risk factor for chronic allograft nephropathy (CAN) and dose reduction has been advocated. The purpose of this study was to…”
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Barriers in the developing brain and Neurotoxicology by Ek, C. Joakim, Dziegielewska, Katarzyna M., Habgood, Mark D., Saunders, Norman R.

“…The brain develops and grows within a well-controlled internal environment that is provided by cellular exchange mechanisms in the interfaces between blood,…”
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