Search Results - "Saunders, M. A"

Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies by Harrington, C, Sawchak, S, Chiang, C, Davies, J, Donovan, C, Saunders, A M, Irizarry, M, Jeter, B, Zvartau-Hind, M, van Dyck, C H, Gold, M

“…Two phase 3 studies evaluated the efficacy and safety of rosiglitazone (RSG), a type 2 diabetes treatment, in an extended release (RSG XR) form as adjunctive…”
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Observation of Betatron X-Ray Radiation in a Self-Modulated Laser Wakefield Accelerator Driven with Picosecond Laser Pulses by Albert, F, Lemos, N, Shaw, J L, Pollock, B B, Goyon, C, Schumaker, W, Saunders, A M, Marsh, K A, Pak, A, Ralph, J E, Martins, J L, Amorim, L D, Falcone, R W, Glenzer, S H, Moody, J D, Joshi, C

“…We investigate a new regime for betatron x-ray emission that utilizes kilojoule-class picosecond lasers to drive wakes in plasmas. When such laser pulses with…”
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Demonstration of X-ray Thomson scattering as diagnostics for miscibility in warm dense matter by Frydrych, S., Vorberger, J., Hartley, N. J., Schuster, A. K., Ramakrishna, K., Saunders, A. M., van Driel, T., Falcone, R. W., Fletcher, L. B., Galtier, E., Gamboa, E. J., Glenzer, S. H., Granados, E., MacDonald, M. J., MacKinnon, A. J., McBride, E. E., Nam, I., Neumayer, P., Pak, A., Voigt, K., Roth, M., Sun, P., Gericke, D. O., Döppner, T., Kraus, D.

“…The gas and ice giants in our solar system can be seen as a natural laboratory for the physics of highly compressed matter at temperatures up to thousands of…”
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Formation of diamonds in laser-compressed hydrocarbons at planetary interior conditions by Kraus, D., Vorberger, J., Pak, A., Hartley, N. J., Fletcher, L. B., Frydrych, S., Galtier, E., Gamboa, E. J., Gericke, D. O., Glenzer, S. H., Granados, E., MacDonald, M. J., MacKinnon, A. J., McBride, E. E., Nam, I., Neumayer, P., Roth, M., Saunders, A. M., Schuster, A. K., Sun, P., van Driel, T., Döppner, T., Falcone, R. W.

“…The effects of hydrocarbon reactions and diamond precipitation on the internal structure and evolution of icy giant planets such as Neptune and Uranus have…”
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Experimental Observations of Laser-Driven Tin Ejecta Microjet Interactions by Saunders, A. M., Stan, C. V., Mackay, K. K., Morgan, B., Horwitz, J. A. K., Ali, S. J., Rinderknecht, H. G., Haxhimali, T., Ping, Y., Najjar, F., Eggert, J., Park, H.-S.

“…The study of high-velocity particle-laden flow interactions is of importance for the understanding of a wide range of natural phenomena, ranging from planetary…”
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Liquid Structure of Shock-Compressed Hydrocarbons at Megabar Pressures by Hartley, N J, Vorberger, J, Döppner, T, Cowan, T, Falcone, R W, Fletcher, L B, Frydrych, S, Galtier, E, Gamboa, E J, Gericke, D O, Glenzer, S H, Granados, E, MacDonald, M J, MacKinnon, A J, McBride, E E, Nam, I, Neumayer, P, Pak, A, Rohatsch, K, Saunders, A M, Schuster, A K, Sun, P, van Driel, T, Kraus, D

“…We present results for the ionic structure in hydrocarbons (polystyrene, polyethylene) that were shock compressed to pressures of up to 190 GPa, inducing rapid…”
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Comparison of nutrient-removing microbial communities in activated sludge from full-scale MBRs and conventional plants by SAUNDERS, A. M, LARSEN, P, NIELSEN, P. H

“…The composition of nutrient-removing microbial communities in five full-scale membrane bioreactors (MBRs) was investigated using fluorescence in situ…”
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Using Genetics to Enable Studies on the Prevention of Alzheimer's Disease by Crenshaw, D G, Gottschalk, W K, Lutz, M W, Grossman, I, Saunders, A M, Burke, J R, Welsh-Bohmer, K A, Brannan, S K, Burns, D K, Roses, A D

“…Curing Alzheimer's disease (AD) remains an elusive goal; indeed, it may even prove to be impossible, given the nature of the disease. Although modulating…”
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Nonplanar effects in simulations of laser-driven ejecta microjet experiments by Horwitz, J. A. K., Sun, Y., Pino, J., Morgan, B. E., Mackay, K. K., Najjar, F. M., Ali, S. J., Eggert, J. H., Ping, Y., Park, H.-S., Saunders, A. M.

“…Recent experiments of laser-driven ejecta microjets performed at OMEGA 60 reveal tortuous jets whereby the jets appear to deviate from their initial trajectory…”
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Enhanced biological phosphorus removal in a sequencing batch reactor using propionate as the sole carbon source by Pijuan, M, Saunders, A.M, Guisasola, A, Baeza, J.A, Casas, C, Blackall, L.L

“…An enhanced biological phosphorus removal (EBPR) system was developed in a sequencing batch reactor (SBR) using propionate as the sole carbon source. The…”
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Quantifying the Probability and Causes of the Surprisingly Active 2018 North Atlantic Hurricane Season by Saunders, M. A., Klotzbach, P. J., Lea, A. S. R., Schreck, C. J., Bell, M. M.

“…The 2018 North Atlantic hurricane season was a destructive season with hurricanes Florence and Michael causing significant damage in the southeastern United…”
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The Microbial Database for Danish wastewater treatment plants with nutrient removal (MiDas-DK) ― a tool for understanding activated sludge population dynamics and community stability by MIELCZAREK, A. T, SAUNDERS, A. M, LARSEN, P, ALBERTSEN, M, STEVENSON, M, NIELSEN, J. L, NIELSEN, P. H

“…Since 2006 more than 50 Danish full-scale wastewater treatment plants with nutrient removal have been investigated in a project called 'The Microbial Database…”
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Patterns of Brain Activation in People at Risk for Alzheimer's Disease by Bookheimer, Susan Y, Strojwas, Magdalena H, Cohen, Mark S, Saunders, Ann M, Pericak-Vance, Margaret A, Mazziotta, John C, Small, Gary W

“…Alzheimer's disease is the most common cause of dementia late in life, affecting approximately 8 percent of people who are 65 years of age or older. 1…”
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Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families by Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., Pericak-Vance, M. A.

“…The apolipoprotein E type 4 allele (APOE-ε4) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease (AD). Risk…”
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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease by Corder, E. H, Saunders, A. M, Risch, N. J, Strittmatter, W. J, Schmechel, D. E, Gaskell, P. C, Rimmler, J. B, Locke, P. A, Conneally, P. M, Schmader, K. E, Small, G. W, Roses, A. D, Haines, J. L, Pericak-Vance, M. A

“…Gene dosage of the apolipoprotein E (APOE) epsilon 4 allele is a major risk factor for familial Alzheimer disease (AD) of late onset (after age 60). Here we…”
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Increased Amyloid β-Peptide Deposition in Cerebral Cortex as a Consequence of Apolipoprotein E Genotype in Late-Onset Alzheimer Disease by Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., Roses, A. D.

“…Amyloid β-peptide (Aβ) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer disease (AD). We examined the possibility…”
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The effect of GAOs (glycogen accumulating organisms) on anaerobic carbon requirements in full-scale Australian EBPR (enhanced biological phosphorus removal) plants by SAUNDERS, A. M, OEHMEN, A, BLACKALL, L. L, YUAN, Z, KELLER, J

“…Glycogen-accumulating organisms (GAOs) were present in six full-scale plants investigated and in all but one made a significant contribution to the amount of…”
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Apolipoprotein E: High-Avidity Binding to β-Amyloid and Increased Frequency of Type 4 Allele in Late-Onset Familial Alzheimer Disease by Strittmatter, Warren J., Saunders, Ann M., Schmechel, Donald, Pericak-Vance, Margaret, Enghild, Jan, Salvesen, Guy S., Roses, Allen D.

“…Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer disease. In vitro,…”
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A variational principle for computing nonequilibrium fluxes and potentials in genome-scale biochemical networks by Fleming, R.M.T., Maes, C.M., Saunders, M.A., Ye, Y., Palsson, B.Ø.

“…We derive a convex optimization problem on a steady-state nonequilibrium network of biochemical reactions, with the property that energy conservation and the…”
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Binding of Human Apolipoprotein E to Synthetic Amyloid β Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease by Strittmatter, Warren J., Weisgraber, Karl H., Huang, David Y., Dong, Li-Ming, Salvesen, Guy S., Pericak-Vance, Margaret, Schmechel, Donald, Saunders, Ann M., Goldgaber, Dmitry, Roses, Allen D.

“…Apolipoprotein E (apoE), a plasma apolipoprotein that plays a central role in lipoprotein metabolism, is localized in the senile plaques, congophilic…”
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