Search Results - "Saunders, F. W"
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Discovering sequence motifs with arbitrary insertions and deletions
Published in PLoS computational biology (09-05-2008)“…BIOLOGY IS ENCODED IN MOLECULAR SEQUENCES: deciphering this encoding remains a grand scientific challenge. Functional regions of DNA, RNA, and protein…”
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Predikin webserver: improved prediction of protein kinase peptide specificity using structural information
Published in Nucleic acids research (01-07-2008)“…The Predikin webserver allows users to predict substrates of protein kinases. The Predikin system is built from three components: a database of protein kinase…”
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3
Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents
Published in PloS one (31-10-2007)“…Crystallization is a major bottleneck in the process of macromolecular structure determination by X-ray crystallography. Successful crystallization requires…”
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4
Haem-ligand switching during catalysis in crystals of a nitrogen-cycle enzyme
Published in Nature (London) (25-09-1997)“…Cytochrome cd1 nitrite reductase catalyses the conversion of nitrite to nitric oxide in the nitrogen cycle. The crystal structure of the oxidized enzyme shows…”
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Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites
Published in BMC bioinformatics (26-05-2008)“…We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies…”
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VariantSpark: population scale clustering of genotype information
Published in BMC genomics (10-12-2015)“…Genomic information is increasingly used in medical practice giving rise to the need for efficient analysis methodology able to cope with thousands of…”
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A panel of genes methylated with high frequency in colorectal cancer
Published in BMC cancer (31-01-2014)“…The development of colorectal cancer (CRC) is accompanied by extensive epigenetic changes, including frequent regional hypermethylation particularly of gene…”
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Serpins in unicellular Eukarya, Archaea, and Bacteria: sequence analysis and evolution
Published in Journal of molecular evolution (01-10-2004)“…Most serpins irreversibly inactivate specific serine proteinases of the chymotrypsin family. Inhibitory serpins are unusual proteins in that their native…”
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The detection of wave slamming from vibration measurements on a polar supply and research vessel
Published in MATEC Web of Conferences (01-01-2018)“…The SA Agulhas II is a polar supply and research vessel, which operates in the stormy Southern ocean and icy Antarctic waters. She is predisposed to…”
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Cold Adaptation of the Antarctic Archaeon, Methanococcoides burtonii Assessed by Proteomics Using ICAT
Published in Journal of proteome research (01-03-2005)“…Using isotope coded affinity tag (ICAT) chromatography and liquid chromatography−mass spectrometry, 163 proteins were identified from the cold-adapted…”
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Beyond Marks: New Tools to Visualise Student Engagement via Social Networks
Published in Research in learning technology (01-01-2012)“…Evidence shows that engaged students perform better academically than disinterested students. Measurement of engagement with education is difficult and…”
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Molecular basis for specificity of nuclear import and prediction of nuclear localization
Published in Biochimica et biophysica acta (01-09-2011)“…Although proteins are translated on cytoplasmic ribosomes, many of these proteins play essential roles in the nucleus, mediating key cellular processes…”
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Disruption of the Pseudomonas aeruginosa dipZ gene, encoding a putative protein-disulfide reductase, leads to partial pleiotropic deficiency in c-type cytochrome biogenesis
Published in Microbiology (Society for General Microbiology) (01-10-1997)“…Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK The Oxford Centre for Molecular Sciences, New Chemistry Building, South…”
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Proteomic and Electron Microscopy Survey of Large Assemblies in Macrophage Cytoplasm
Published in Molecular & cellular proteomics (01-06-2011)“…Many cellular processes are carried out by large macromolecular assemblies. We systematically analyzed large macromolecular assemblies in the cytoplasm of…”
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An online database for the detection of novel archaeal sequences in human ESTs
Published in Bioinformatics (12-10-2004)“…We have developed a rapid, automated screening system and online database to detect foreign sequences of archaeal origin in human expressed sequence tags. The…”
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Thermography: Its relation to pathologic characteristics, vascularity, proliferation rate, and survival of patients with invasive ductal carcinoma of the breast
Published in Cancer (01-04-1996)“…BACKGROUND The reason for the thermal abnormality associated with some breast cancers is unclear. We previously reported that a thermographic abnormality is…”
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Topical glyceryltrinitrate causes measurable penile arterial dilation in impotent men
Published in The Journal of urology (01-04-1990)“…The current understanding of the intracavernous changes that cause or accompany penile erections has encouraged the use of vasodilators as therapy for erectile…”
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Transcription regulation of the nir gene cluster encoding nitrite reductase of Paracoccus denitrificans involves NNR and NirI, a novel type of membrane protein
Published in Molecular microbiology (01-10-1999)“…The nirIX gene cluster of Paracoccus denitrificans is located between the nir and nor gene clusters encoding nitrite and nitric oxide reductases respectively…”
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The NosX and NirX Proteins of Paracoccus denitrificans Are Functional Homologues: Their Role in Maturation of Nitrous Oxide Reductase
Published in Journal of Bacteriology (01-09-2000)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Circadian rhythm of cerebral perfusion pressure and intracranial pressure in head injury
Published in Brain injury (1999)“…The aim of the study was to determine if Cerebral Perfusion Pressure CPP and Intracranial Pressure ICP, in patients with head injury, has a circadian rhythm…”
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