Search Results - "Saunders, Bernadette"
-
1
Treatment for non-tuberculous mycobacteria: challenges and prospects
Published in Frontiers in microbiology (03-06-2024)“…Non-Tuberculous mycobacteria (NTM) are opportunistic environmental bacteria. Globally, NTM incidence is increasing and modeling suggests that, without new…”
Get full text
Journal Article -
2
Biomarkers for Detecting Resilience against Mycobacterial Disease in Animals
Published in Infection and immunity (17-12-2019)“…Paratuberculosis and bovine tuberculosis are two mycobacterial diseases of ruminants which have a considerable impact on livestock health, welfare, and…”
Get full text
Journal Article -
3
A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment
Published in Immunity (Cambridge, Mass.) (15-08-2017)“…The liver is positioned at the interface between two routes traversed by pathogens in disseminating infection. Whereas blood-borne pathogens are efficiently…”
Get full text
Journal Article -
4
The role of the P2X₇ receptor in infectious diseases
Published in PLoS pathogens (01-11-2011)“…ATP is an extracellular signal for the immune system, particularly during an inflammatory response. It is sensed by the P2X₇ receptor, the expression of which…”
Get full text
Journal Article -
5
Targets and regulation of microRNA-652-3p in homoeostasis and disease
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2021)“…microRNA are small non-coding RNA molecules which inhibit gene expression by binding mRNA, preventing its translation. As important regulators of gene…”
Get full text
Journal Article -
6
Life and death in the granuloma: immunopathology of tuberculosis
Published in Immunology and cell biology (01-02-2007)“…During tuberculosis (TB) infection, the granuloma provides the microenvironment in which antigen‐specific T cells colocate with and activate infected…”
Get full text
Journal Article -
7
Strengthening the Connection Between Acquired Brain Injury (ABI) and Family Violence: The Importance of Ongoing Monitoring, Research and Inclusive Terminology
Published in Journal of family violence (01-02-2022)“…Family violence (FV) harms communities worldwide so FV prevention strategies and effective responses are urgently needed. This article reports on FV apparent…”
Get full text
Journal Article -
8
Aboriginal and Torres Strait Islander (Indigenous) young people leaving out-of-home care in Australia: A national scoping study
Published in Children and youth services review (01-02-2021)“…•Indigenous care leavers appear to have unique experiences and needs compared to other care leavers in Australia.•Specific funding and resources to support…”
Get full text
Journal Article -
9
Children's Human Rights and Social Work Advocacy: "Lawful Correction"
Published in Australian social work (02-10-2019)“…In Australia, adults are afforded greater protection from assault than children. The "lawful correction" defence stems from an 1860 UK judgement that condoned…”
Get full text
Journal Article -
10
Healing Trauma and Loss and Increasing Social Connections: Transitions from Care and Early Parenting
Published in Child & adolescent social work journal (01-12-2022)“…International literature suggests that many young people transitioning from government care become parents before age 21, characteristically termed ‘early…”
Get full text
Journal Article -
11
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection
Published in PloS one (23-05-2012)“…Indoleamine 2,3-dioxygenesae-1 (IDO-1) catalyses the initial, rate-limiting step in tryptophan metabolism, thereby regulating tryptophan availability and the…”
Get full text
Journal Article -
12
Salmonella employs multiple mechanisms to subvert the TLR‐inducible zinc‐mediated antimicrobial response of human macrophages
Published in The FASEB journal (01-05-2016)“…We aimed to characterize antimicrobial zinc trafficking within macrophages and to determine whether the professional intramacrophage pathogen Salmonella…”
Get full text
Journal Article -
13
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
Published in American journal of respiratory and critical care medicine (15-09-2022)“…Patients with chronic obstructive pulmonary disease (COPD) develop more severe coronavirus disease (COVID-19); however, it is unclear whether they are more…”
Get full text
Journal Article -
14
Developing new TB biomarkers, are miRNA the answer?
Published in Tuberculosis (Edinburgh, Scotland) (01-09-2019)“…Efforts to reduce the global TB burden are hindered by the lack of simple, reliable non-sputum based diagnostics. To date studies investigating the biomarker…”
Get full text
Journal Article -
15
Macrophages of different tissue origin exhibit distinct inflammatory responses to mycobacterial infection
Published in Immunology and cell biology (01-11-2021)“…Macrophages display marked plasticity with functions in both inflammation and tissue repair. Evidence demonstrates that this spectrum of macrophage phenotypes…”
Get full text
Journal Article -
16
Mycobacterium bovis BCG-Specific Th17 Cells Confer Partial Protection against Mycobacterium tuberculosis Infection in the Absence of Gamma Interferon
Published in Infection and Immunity (01-10-2010)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
17
High-resolution longitudinal N- and O-glycoprofiling of human monocyte-to-macrophage transition
Published in Glycobiology (Oxford) (20-08-2020)“…Protein glycosylation impacts the development and function of innate immune cells. The glycophenotypes and the glycan remodelling associated with the…”
Get full text
Journal Article -
18
P2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP
Published in The Journal of immunology (1950) (01-09-2011)“…Abstract Phagocytosis of apoptotic cells is essential during development and tissue remodeling. Our previous study has shown that the P2X7 receptor regulates…”
Get full text
Journal Article -
19
Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
Published in Immunity (Cambridge, Mass.) (14-12-2021)“…Viral mutations are an emerging concern in reducing SARS-CoV-2 vaccination efficacy. Second-generation vaccines will need to elicit neutralizing antibodies…”
Get full text
Journal Article -
20
Identification of a plasma microRNA profile in untreated pulmonary tuberculosis patients that is modulated by anti-mycobacterial therapy
Published in The Journal of infection (01-10-2018)“…•Identified 87 miRs differentially regulated in TB patients versus healthy controls.•5 miRNA signature has biomarker potential to identify active TB…”
Get full text
Journal Article