Search Results - "Saul, F. A."

Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody by Vulliez-Le Normand, B, Saul, F.A, Phalipon, A, Bélot, F, Guerreiro, C, Mulard, L.A, Bentley, G.A

“…The anti-LPS IgG mAb F22-4, raised against Shigella flexneri serotype 2a bacteria, protects against homologous, but not heterologous, challenge in an…”
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Structural and Functional Studies of FkpA from Escherichia coli, a cis/ trans Peptidyl-prolyl Isomerase with Chaperone Activity by Saul, F.A., Arié, J.-P., Vulliez-le Normand, B., Kahn, R., Betton, J.-M., Bentley, G.A.

“…The protein FkpA from the periplasm of Escherichia coli exhibits both cis/ trans peptidyl-prolyl isomerase (PPIase) and chaperone activities. The crystal…”
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On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5 by Novotny, Jiri, Bruccoleri, Robert E, Saul, Frederick A

“…Using X-ray coordinates of antigen-antibody complexes McPC 603, D1.3, and HyHEL-5, we made semiquantitative estimates of Gibbs free energy changes (delta G)…”
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Crystal structure of a dominant B-cell epitope from the pres2 region of hepatitis B virus in the form of an inserted peptide segment in maltodextrin-binding protein by Saul, F.A, Normand, B.Vulliez-le, Lema, F, Bentley, G.A

“…We report here the crystal structure of MalE-B363, a recombinant construction of maltodextrin-binding protein bearing a dominant B-cell epitope sequence from…”
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Crystal structure of a recombinant form of the maltodextrin-binding protein carrying an inserted sequence of a B-cell epitope from the preS2 region of hepatitis B virus by Saul, F. A., Normand, B. Vulliez-le, Lema, F., Bentley, G. A.

“…We report the crystal structure of MalE‐B133, a recombinant form of the maltodextrin‐binding protein (MBP) of Escherichia coli carrying an inserted amino‐acid…”
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Structural Mimicry of O-Antigen by a Peptide Revealed in a Complex with an Antibody Raised against Shigella flexneri Serotype 2a by Theillet, François-Xavier, Saul, Frederick A., Vulliez-Le Normand, Brigitte, Hoos, Sylviane, Felici, Franco, Weintraub, Andrej, Mulard, Laurence A., Phalipon, Armelle, Delepierre, Muriel, Bentley, Graham A.

“…The use of carbohydrate-mimicking peptides to induce immune responses against surface polysaccharides of pathogenic bacteria offers a novel approach to vaccine…”
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Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution by Saul, F A, Amzel, L M, Poljak, R J

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Maltodextrin-binding protein hybrids carrying epitopes from the preS2 region of hepatitis B virus: expression, antibody-binding and preliminary crystallographic studies by Vulliez-le Normand, B, Saul, F A, Martineau, P, Lema, F, Hofnung, M, Bentley, G A

“…Five hybrid constructions of maltodextrin-binding protein (MBP), each containing an inserted epitope(s) from the preS2 region of the envelope proteins of…”
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Crystal structure of Urtica dioica agglutinin, a superantigen presented by MHC molecules of class I and class II by Saul, Frederick A, Rovira, Paula, Boulot, Ginette, Van Damme, Els JM, Peumans, Willy J, Truffa-Bachi, Paolo, Bentley, Graham A

“…Background: Urtica dioica agglutinin (UDA), a monomeric lectin extracted from stinging nettle rhizomes, is specific for saccharides containing…”
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Structure of the Fab fragment from F124, a monoclonal antibody specific for hepatitis B surface antigen by Saul, F. A., Vulliez-le Normand, B., Passafiume, M., Riottot, M.-M., Bentley, G. A.

“…The crystal structure of the Fab fragment from the monoclonal anti‐preS2 antibody F124 (IgG1,κ) has been solved by molecular replacement and refined at 3.0 Å…”
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Crystallographic studies of antigen-antibody interactions by Saul, F A, Alzari, P M

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Studies of Structure and Specificity of Some Antigen-Antibody Complexes by Bentley, G. A., Alzari, P. M., Amit, A. G., Boulot, G., Guillon-Chitarra, V., Fischmann, T., M.-B. Lascombe, Mariuzza, R. A., Poljak, R. J., M.-M. Riottot, Saul, F. A., Souchon, H., Tello, D.

“…By using X-ray diffraction and immunochemical techniques, we have exploited the use of monoclonal antibodies raised against hen egg lysozyme (HEL) to study…”
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Crystallization of the fab fragments of monoclonal anti-p-azophenylarsonate antibodies and their complexes with haptens by Mariuzza, R A, Amit, A G, Boulot, G, Saludjian, P, Saul, F A, Tougard, P, Poljak, R J, Conger, J, Lamoyi, E, Nisonoff, A

“…We report on the preparation, crystallization, and preliminary x-ray crystallographic study of Fab fragments from monoclonal anti-p-azophenylarsonate…”
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Crystal structure of human immunoglobulin fragment Fab New refined at 2.0 A resolution by Saul, F A, Poljak, R J

“…The three-dimensional structure of the human immunoglobulin fragment Fab New (IgG1, lambda) has been refined to a crystallographic R-factor of 16.9% to 2 A…”
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Structural patterns at residue positions 9, 18, 67 and 82 in the VH framework regions of human and murine immunoglobulins by Saul, F A, Poljak, R J

“…VH framework regions of human and mouse immunoglobulins display three characteristic patterns in the conformation of the main polypeptide chain and side-chains…”
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Structure and specificity of antibody molecules by Saul, F A, Poljak, R J

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Three-dimensional structure and antigen binding specificity of antibodies by Tello, D, Spinelli, S, Souchon, H, Saul, F A, Riottot, M M, Mariuzza, R A, Lascombe, M B, Houdusse, A, Eiselé, J L, Fischmann, T

“…A number of specific Fab and Fv fragments and their complexes with antigens (avian lysozymes), haptens, and anti-idiotopic Fabs have been studied by…”
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Structural implications of VH sequence patterns by Saul, F A

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Crystal structure of a defective folding protein by Saul, Frederick A., Mourez, Michaël, Vulliez‐le Normand, Brigitte, Sassoon, Nathalie, Bentley, Graham A., Betton, Jean‐Michel

“…Maltose‐binding protein (MBP or MalE) of Escherichia coli is the periplasmic receptor of the maltose transport system. MalE31, a defective folding mutant of…”
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X-ray diffraction studies of an anti-azophenylarsonate antibody and of an antigen-antibody complex by Amit, A G, Boulot, G, Comarmond, M B, Harper, M, Mariuzza, R A, Phillips, S E, Saludjian, P, Saul, F A, Souchon, H, Tougard, P

“…X-ray crystallographic studies of the Fab fragments of two murine monoclonal antibodies of predefined specificity are under way. Diffracted X-ray intensities…”
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