Search Results - "Saudino, Giovanni"
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Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 Caused by CYS59TYR BOLA3 Mutation
Published in International journal of molecular sciences (03-05-2021)“…Multiple mitochondrial dysfunctions syndrome (MMDS) is a rare neurodegenerative disorder associated with mutations in genes with a vital role in the biogenesis…”
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Optimization of a Bacterial Cultivation Medium via a Design-of-Experiment Approach in a Sartorius Ambr® 15 Fermentation Microbioreactor System
Published in Fermentation (Basel) (01-12-2023)“…In the evolving landscape of sustainable biopharmaceutical process development, the utilization of bacteria in the production of various compounds via…”
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Protein-Interaction Affinity Gradient Drives [4Fe–4S] Cluster Insertion in Human Lipoyl Synthase
Published in Journal of the American Chemical Society (06-04-2022)“…Human lipoyl synthase (LIAS) is an enzyme containing two [4Fe–4S] clusters (named FeSRS and FeSaux) involved in the biosynthesis of the lipoyl cofactor. The…”
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Protein-Interaction Affinity Gradient Drives 4Fe-4S Cluster Insertion in Human Lipoyl Synthase
Published in Journal of the American Chemical Society (06-04-2022)“…Human lipoyl synthase (LIAS) is an enzyme containing two [4Fe-4S] clusters (named FeSRS and FeSaux) involved in the biosynthesis of the lipoyl cofactor. The…”
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ISCA1 Orchestrates ISCA2 and NFU1 in the Maturation of Human Mitochondrial [4Fe-4S] Proteins
Published in Journal of molecular biology (14-05-2021)“…[Display omitted] •ISCA1, ISCA2 and NFU1 are implicated in mitochondrial [4Fe-4S] protein biogenesis.•ISCA1, interacting with ISCA2 and NFU1, promotes the…”
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Structural Plasticity of NFU1 Upon Interaction with Binding Partners: Insights into the Mitochondrial [4Fe-4S] Cluster Pathway
Published in Journal of molecular biology (01-08-2023)“…[Display omitted] •Protein-protein interactions maturing mitochondrial [4Fe-4S] protein.•Structural modelling of ISCA1-ISCA2, ISCA1-ISCA2-NFU1, ISCA1-NFU1 apo…”
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3D Analysis of Ordered Porous Polymeric Particles using Complementary Electron Microscopy Methods
Published in Scientific reports (27-09-2019)“…Highly porous particles with internal triply periodic minimal surfaces were investigated for sorption of proteins. The visualization of the complex ordered…”
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